Search Results - "Lechner, Beatrix E."

ChIP-seq and in vivo transcriptome analyses of the Aspergillus fumigatus SREBP SrbA reveals a new regulator of the fungal hypoxia response and virulence by Chung, Dawoon, Barker, Bridget M, Carey, Charles C, Merriman, Brittney, Werner, Ernst R, Lechner, Beatrix E, Dhingra, Sourabh, Cheng, Chao, Xu, Wenjie, Blosser, Sara J, Morohashi, Kengo, Mazurie, Aurélien, Mitchell, Thomas K, Haas, Hubertus, Mitchell, Aaron P, Cramer, Robert A

“…The Aspergillus fumigatus sterol regulatory element binding protein (SREBP) SrbA belongs to the basic Helix-Loop-Helix (bHLH) family of transcription factors…”
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Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus by Wiemann, Philipp, Lechner, Beatrix E, Baccile, Joshua A, Velk, Thomas A, Yin, Wen-Bing, Bok, Jin Woo, Pakala, Suman, Losada, Liliana, Nierman, William C, Schroeder, Frank C, Haas, Hubertus, Keller, Nancy P

“…Iron plays a critical role in survival and virulence of the opportunistic pathogen Aspergillus fumigatus. Two transcription factors, the GATA-factor SreA and…”
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Iron-sensing is governed by mitochondrial, not by cytosolic iron-sulfur cluster biogenesis in Aspergillus fumigatus by Misslinger, Matthias, Lechner, Beatrix E, Bacher, Katharina, Haas, Hubertus

“…Microorganisms have to adapt their metabolism to the requirements of their ecological niche to avoid iron shortage as well as iron toxicity. Therefore,…”
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Pseudomonas aeruginosa manipulates redox and iron homeostasis of its microbiota partner Aspergillus fumigatus via phenazines by Briard, Benoit, Bomme, Perrine, Lechner, Beatrix E., Mislin, Gaëtan L. A., Lair, Virginie, Prévost, Marie-Christine, Latgé, Jean-Paul, Haas, Hubertus, Beauvais, Anne

“…The opportunistic fungal pathogen Aspergillus fumigatus is increasingly found as a coinfecting agent along with Pseudomonas aeruginosa in cystic fibrosis…”
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The Janus transcription factor HapX controls fungal adaptation to both iron starvation and iron excess by Gsaller, Fabio, Hortschansky, Peter, Beattie, Sarah R, Klammer, Veronika, Tuppatsch, Katja, Lechner, Beatrix E, Rietzschel, Nicole, Werner, Ernst R, Vogan, Aaron A, Chung, Dawoon, Mühlenhoff, Ulrich, Kato, Masashi, Cramer, Robert A, Brakhage, Axel A, Haas, Hubertus

“…Balance of physiological levels of iron is essential for every organism. In Aspergillus fumigatus and other fungal pathogens , the transcription factor HapX…”
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Modifying the Siderophore Triacetylfusarinine C for Molecular Imaging of Fungal Infection by Kaeopookum, Piriya, Summer, Dominik, Pfister, Joachim, Orasch, Thomas, Lechner, Beatrix E., Petrik, Milos, Novy, Zbynek, Matuszczak, Barbara, Rangger, Christine, Haas, Hubertus, Decristoforo, Clemens

“…Purpose Aspergillus fumigatus produces the siderophore triacetylfusarinine C (TAFC) for iron acquisition which is essential for its virulence. Therefore, TAFC…”
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Exploiting the Concept of Multivalency with 68Ga- and 89Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression by Decristoforo, Clemens, von Guggenberg, Elisabeth, Orasch, Thomas, Lechner, Beatrix E., Franssen, Gerben M., Laverman, Peter, Klingler, Maximilian, Rangger, Christine, Summer, Dominik, Haas, Hubertus

“…Cholecystokinin-2 receptors (CCK2R) are overexpressed in a variety of malignant diseases and therefore have gained certain attention for peptide receptor…”
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Genome mining and functional genomics for siderophore production in Aspergillus niger by Franken, Angelique C W, Lechner, Beatrix E, Werner, Ernst R, Haas, Hubertus, Lokman, B Christien, Ram, Arthur F J, van den Hondel, Cees A M J J, de Weert, Sandra, Punt, Peter J

“…Iron is an essential metal for many organisms, but the biologically relevant form of iron is scarce because of rapid oxidation resulting in low solubility…”
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Iron-sensing is governed by mitochondrial, not by cytosolic iron-sulfur cluster biogenesis in Aspergillus fumigatusElectronic supplementary information (ESI) available. See DOI: 10.1039/c8mt00263k by Misslinger, Matthias, Lechner, Beatrix E, Bacher, Katharina, Haas, Hubertus

“…Microorganisms have to adapt their metabolism to the requirements of their ecological niche to avoid iron shortage as well as iron toxicity. Therefore,…”
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Iron-sensing is governed by mitochondrial, not by cytosolic iron–sulfur cluster biogenesis in Aspergillus fumigatus† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8mt00263k by Misslinger, Matthias, Lechner, Beatrix E., Bacher, Katharina, Haas, Hubertus

“…Microorganisms have to adapt their metabolism to the requirements of their ecological niche to avoid iron shortage as well as iron toxicity. Microorganisms…”
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Exploiting the Concept of Multivalency with 68 Ga- and 89 Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression by Summer, Dominik, Rangger, Christine, Klingler, Maximilian, Laverman, Peter, Franssen, Gerben M., Lechner, Beatrix E., Orasch, Thomas, Haas, Hubertus, von Guggenberg, Elisabeth, Decristoforo, Clemens

“…Cholecystokinin-2 receptors (CCK2R) are overexpressed in a variety of malignant diseases and therefore have gained certain attention for peptide receptor…”
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The J anus transcription factor H ap X controls fungal adaptation to both iron starvation and iron excess by Gsaller, Fabio, Hortschansky, Peter, Beattie, Sarah R, Klammer, Veronika, Tuppatsch, Katja, Lechner, Beatrix E, Rietzschel, Nicole, Werner, Ernst R, Vogan, Aaron A, Chung, Dawoon, Mühlenhoff, Ulrich, Kato, Masashi, Cramer, Robert A, Brakhage, Axel A, Haas, Hubertus

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ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence: e1004487 by Chung, Dawoon, Barker, Bridget M, Carey, Charles C, Merriman, Brittney, Werner, Ernst R, Lechner, Beatrix E, Dhingra, Sourabh, Cheng, Chao, Xu, Wenjie, Blosser, Sara J, Morohashi, Kengo, Mazurie, Aurélien, Mitchell, Thomas K, Haas, Hubertus, Mitchell, Aaron P, Cramer, Robert A

“…The Aspergillus fumigatus sterol regulatory element binding protein (SREBP) SrbA belongs to the basic Helix-Loop-Helix (bHLH) family of transcription factors…”
Get full text

Exploiting the Concept of Multivalency with 68 Ga- and 89 Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression by Summer, Dominik, Rangger, Christine, Klingler, Maximilian, Laverman, Peter, Franssen, Gerben M, Lechner, Beatrix E, Orasch, Thomas, Haas, Hubertus, von Guggenberg, Elisabeth, Decristoforo, Clemens

“…Cholecystokinin-2 receptors (CCK2R) are overexpressed in a variety of malignant diseases and therefore have gained certain attention for peptide receptor…”
Get full text