Search Results - "Lechat, P"

Transfer for primary angioplasty versus immediate thrombolysis in acute myocardial infarction: A meta-analysis by DALBY, M, BOUZAMONDO, A, LECHAT, P, MONTALESCOT, G

“…The benefit of primary percutaneous coronary intervention (PCI) over thrombolysis has been clearly demonstrated in acute myocardial infarction (AMI). However,…”
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Drug eluting stents: an updated meta-analysis of randomised controlled trials by Roiron, C, Sanchez, P, Bouzamondo, A, Lechat, P, Montalescot, G

“…Objective: To confirm the overall benefit of drug eluting stents (DES), to evaluate the effect of different DES, and to assess the global safety of DES…”
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Prevention of cardiovascular events in end-stage renal disease: Results of a randomized trial of fosinopril and implications for future studies by Zannad, F., Kessler, M., Lehert, P., Grünfeld, J.P., Thuilliez, C., Leizorovicz, A., Lechat, P., for the Fosidial Investigators

“…Cardiovascular events (CVEs) are the leading cause of death in chronic hemodialysis patients. Results of trials in non-end-stage renal disease (ESRD) patients…”
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Effect on survival and hospitalization of initiating treatment for chronic heart failure with bisoprolol followed by enalapril, as compared with the opposite sequence : Results of the randomized cardiac insufficiency bisoprolol study (CIBIS) III by WILLENHEIMER, Ronnie, VAN VELDHUISEN, Dirk J, LECHAT, Philippe, SILKE, Bernard, ERDMANN, Erland, FOLLATH, Ferenc, KRUM, Henry, PONIKOWSKI, Piotr, SKENE, Allan, VAN DE VEN, Louis, VERKENNE, Patricia

“…In patients with chronic heart failure (CHF), a beta-blocker is generally added to a regimen containing an angiotensin-converting-enzyme (ACE) inhibitor. It is…”
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Deficiency of the 5-hydroxytryptamine transporter gene leads to cardiac fibrosis and valvulopathy in mice by MEKONTSO-DESSAP, A, BROURI, F, ADNOT, S, EDDAHIBI, S, PASCAL, O, LECHAT, P, HANOUN, N, LANFUMEY, L, SEIF, I, BENHAIEM-SIGAUX, N, KIRSCH, M, HAMON, M

“…Serotonin (5-hydroxytryptamine; 5-HT) overproduction is responsible for cardiac valvular disease in patients with carcinoid tumors. Reduced 5-HT inactivation…”
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Prevention of atrial fibrillation onset by beta-blocker treatment in heart failure: a meta-analysis by Nasr, Imad Abi, Bouzamondo, Anissa, Hulot, Jean-Sébastien, Dubourg, Olivier, Le Heuzey, Jean-Yves, Lechat, Philippe

“…Aims Atrial fibrillation (AF) is an important morbidity-mortality risk factor, especially in patients with heart failure (HF). Beta-blockers reduce morbidity…”
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Impact of ABCC2 polymorphisms on high-dose methotrexate pharmacokinetics in patients with lymphoid malignancy by Simon, N, Marsot, A, Villard, E, Choquet, S, Khe, H-X, Zahr, N, Lechat, P, Leblond, V, Hulot, J-S

“…Human multidrug resistance-related protein 2 (MRP2, encoded by ABCC2 ) is involved in the transport of anionic drugs such as methotrexate (MTX). We…”
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Changes in Enoxaparin Pharmacokinetics During Pregnancy and Implications for Antithrombotic Therapeutic Strategy by Lebaudy, C, Hulot, JS, Amoura, Z, Costedoat‐Chalumeau, N, Serreau, R, Ankri, A, Conard, J, Cornet, A, Dommergues, M, Piette, JC, Lechat, P

“…Enoxaparin is frequently prescribed for pregnant women who are at high risk for thromboembolic complications. We conducted a population pharmacokinetics study…”
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Heart conduction disorders related to antimalarials toxicity: an analysis of electrocardiograms in 85 patients treated with hydroxychloroquine for connective tissue diseases by Costedoat-Chalumeau, N., Hulot, J.-S., Amoura, Z., Leroux, G., Lechat, P., Funck-Brentano, C., Piette, J.-C.

“…Objective. The antimalarial agents chloroquine (CQ) and hydroxychloroquine (HCQ) are used in long-term treatment of connective tissue diseases (CTDs). A high…”
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Sensitive determination of tenofovir in human plasma samples using reversed-phase liquid chromatography by Sentenac, S., Fernandez, C., Thuillier, A., Lechat, P., Aymard, G.

“…A new high-performance liquid chromatography assay was developed for the determination of tenofovir, a nucleotide analogue, in plasma. A solid–liquid…”
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Prognostic value of bisoprolol-induced hemodynamic effects in heart failure during the cardiac insufficiency BIsoprolol study (CIBIS) by LECHAT, P, ESCOLANO, S, MALLET, A, GOLMARD, J. L, LARDOUX, H, WITCHITZ, S, HENNEMAN, J. A, MAISCH, B, HETZEL, M, JAILLON, P, BOISSEL, J.-P

“…To further evaluate the mechanism of beta-blocker-induced benefits in heart failure, the relationships between bisoprolol-induced hemodynamic effects and…”
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Prognostic value of plasma endothelin-1 in patients with chronic heart failure by Pousset, F., Isnard, R., Lechat, P., Kalotka, H., Carayon, A., Maistre, G., Escolano, S., Thomas, D., Komajda, M.

“…Aims Endothelin-1 is a potent vasoconstrictive and multifunctional peptide. Elevated concentrations have been reported in congestive heart failure. We…”
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Plasma adrenomedullin, a new independent predictor of prognosis in patients with chronic heart failure by Pousset, F, Masson, F, Chavirovskaia, O, Isnard, R, Carayon, A, Golmard, J.L, Lechat, P, Thomas, D, Komajda, M

“…Background Adrenomedullin, a potent endogenous vasodilating and natriuretic peptide, may play an important role in the pathophysiology of chronic heart…”
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Prevention of heart failure progression : Current approaches by LECHAT, P

“…Heart failure results from damage and stress to the myocardium whatever the aetiology. An increase in stress by cardiac overload is initially overcome by…”
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Beta-blocker treatment in heart failure. Role of heart rate reduction by Lechat, P

“…The potential therapeutic effect of beta-blocker treatment in chronic heart failure is still actively being investigated through large scale clinical trials…”
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Tracheal Perforation following Double-Lumen Intubation: A case report by ZINGA, E, DANGOISSE, M, LECHAT, J. P

“…Tracheal perforation following endotracheal intubation is an underestimated complication that seriously compromises prognosis. Treatment can be either…”
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Prognostic benefit of beta-blockers in patients not receiving ACE-Inhibitors by Krum, Henry, Haas, Steven Joseph, Eichhorn, Eric, Ghali, Jalal, Gilbert, Edward, Lechat, Philippe, Packer, Milton, Roecker, Ellen, Verkenne, Patricia, Wedel, Hans, Wikstrand, John

“…Aims Beta-blockers (BBs) confer significant prognostic benefit in patients (pts) with systolic chronic heart failure (CHF). However, major trials have thus far…”
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Connection error in the delivery of medical gases to a surgical unit by DANGOISSE, M. J, LALOT, M, LECHAT, J. P

“…Whilst anesthetic incidents due to problems with the delivery of medical gases to a surgical unit are exceptional, their consequences are potentially drastic…”
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Does the KCE restrictive policy for preoperative testing lead to increased postoperative complications rate ? by GEORGES, P, KREMER, Y, LEDENT, M, LECHAT, J. P, DE KOCK, M

“…The majority of the industrialized country tries to contain the health care costs. One of the solutions applied was to restrict preoperative routine testing…”
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Beta-blocker treatment in heart failure by Bouzamondo, A, Hulot, J S, Sanchez, P, Cucherat, M, Lechat, P

“…Heart failure treatment has markedly changed during the last few decades, with demonstration of benefit of afterload reduction by vasodilator therapy and…”
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