Search Results - "Lechêne, P."

Influence of cell confluence on the cAMP signalling pathway in vascular smooth muscle cells by Belacel-Ouari, M., Zhang, L., Hubert, F., Assaly, R., Gerbier, R., Jockers, R., Dauphin, F., Lechêne, P., Fischmeister, R., Manoury, B., Leblais, V.

“…The influence of cell confluence on the β-adrenoceptor (β-AR)/cAMP/phosphodiesterase (PDE) pathway was investigated in cultured rat aortic smooth muscle cells…”
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Antioxidant Role for Lipid Droplets in a Stem Cell Niche of Drosophila by Bailey, Andrew P., Koster, Grielof, Guillermier, Christelle, Hirst, Elizabeth M.A., MacRae, James I., Lechene, Claude P., Postle, Anthony D., Gould, Alex P.

“…Stem cells reside in specialized microenvironments known as niches. During Drosophila development, glial cells provide a niche that sustains the proliferation…”
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Mammalian heart renewal by pre-existing cardiomyocytes by Senyo, Samuel E., Steinhauser, Matthew L., Pizzimenti, Christie L., Yang, Vicky K., Cai, Lei, Wang, Mei, Wu, Ting-Di, Guerquin-Kern, Jean-Luc, Lechene, Claude P., Lee, Richard T.

“…During normal ageing a low rate of division of pre-existing cardiomyocytes, rather than progenitor cells, is responsible for cardiomyocyte genesis; this…”
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Flexible and stretchable power sources for wearable electronics by Zamarayeva, Alla M, Ostfeld, Aminy E, Wang, Michael, Duey, Jerica K, Deckman, Igal, Lechêne, Balthazar P, Davies, Greg, Steingart, Daniel A, Arias, Ana Claudia

“…Flexible and stretchable power sources represent a key technology for the realization of wearable electronics. Developing flexible and stretchable batteries…”
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Organic solar cells and fully printed super-capacitors optimized for indoor light energy harvesting by Lechêne, Balthazar P., Cowell, Martin, Pierre, Adrien, Evans, James W., Wright, Paul K., Arias, Ana C.

“…Flexibility, lightness and printability make organic solar cells (OSC) strong candidates to power low consumption devices such as envisioned for the Internet…”
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Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism by Steinhauser, Matthew L., Bailey, Andrew P., Senyo, Samuel E., Guillermier, Christelle, Perlstein, Todd S., Gould, Alex P., Lee, Richard T., Lechene, Claude P.

“…Multi-isotope imaging mass spectrometry is used to investigate the ‘immortal strand hypothesis’, Drosophila lipid metabolism and human lymphopoiesis…”
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Materials and methods for higher performance screen‐printed flexible MRI receive coils by Corea, Joseph R., Lechene, P. Balthazar, Lustig, Michael, Arias, Ana C.

“…Purpose To develop methods for characterizing materials used in screen‐printed MRI coils and improve signal‐to‐noise ratio (SNR) with new lower‐loss materials…”
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Quantitative Imaging of Nitrogen Fixation by Individual Bacteria Within Animal Cells by Lechene, Claude P, Luyten, Yvette, McMahon, Gregory, Distel, Daniel L

“…Biological nitrogen fixation, the conversion of atmospheric nitrogen to ammonia for biosynthesis, is exclusively performed by a few bacteria and archaea…”
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Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia by Zhang, Duan-Sun, Piazza, Valeria, Perrin, Benjamin J., Rzadzinska, Agnieszka K., Poczatek, J. Collin, Wang, Mei, Prosser, Haydn M., Ervasti, James M., Corey, David P., Lechene, Claude P.

“…Multi-isotope imaging mass spectrometry is used to quantify protein turnover in animal stereocilia, showing that rapid turnover occurs only in stereocilia…”
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Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear by Drummond, Meghan C., Barzik, Melanie, Bird, Jonathan E., Zhang, Duan-Sun, Lechene, Claude P., Corey, David P., Cunningham, Lisa L., Friedman, Thomas B.

“…The maintenance of sensory hair cell stereocilia is critical for lifelong hearing; however, mechanisms of structural homeostasis remain poorly understood…”
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Imaging mass spectrometry demonstrates age-related decline in human adipose plasticity by Guillermier, Christelle, Fazeli, Pouneh K, Kim, Soomin, Lun, Mingyue, Zuflacht, Jonah P, Milian, Jessica, Lee, Hang, Francois-Saint-Cyr, Hugues, Horreard, Francois, Larson, David, Rosen, Evan D, Lee, Richard T, Lechene, Claude P, Steinhauser, Matthew L

“…Quantification of stable isotope tracers has revealed the dynamic state of living tissues. A new form of imaging mass spectrometry quantifies isotope ratios in…”
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Cardiac Overexpression of PDE4B Blunts β-Adrenergic Response and Maladaptive Remodeling in Heart Failure by Karam, Sarah, Margaria, Jean Piero, Bourcier, Aurélia, Mika, Delphine, Varin, Audrey, Bedioune, Ibrahim, Lindner, Marta, Bouadjel, Kaouter, Dessillons, Matthieu, Gaudin, Françoise, Lefebvre, Florence, Mateo, Philippe, Lechène, Patrick, Gomez, Susana, Domergue, Valérie, Robert, Pauline, Coquard, Charlène, Algalarrondo, Vincent, Samuel, Jane-Lise, Michel, Jean-Baptiste, Charpentier, Flavien, Ghigo, Alessandra, Hirsch, Emilio, Fischmeister, Rodolphe, Leroy, Jérôme, Vandecasteele, Grégoire

“…BACKGROUND:The cyclic AMP (adenosine monophosphate; cAMP)-hydrolyzing protein PDE4B (phosphodiesterase 4B) is a key negative regulator of cardiac β-adrenergic…”
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3D multi-isotope imaging mass spectrometry reveals penetration of 18O-trehalose in mouse sperm nucleus by Lechene, Claude P, Lee, Gloria Y, Poczatek, J Collin, Toner, Mehmet, Biggers, John D

“…The prevalence of genetically engineered mice in medical research has led to ever increasing storage costs. Trehalose has a significant beneficial effect in…”
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Quantitative imaging of subcellular metabolism with stable isotopes and multi-isotope imaging mass spectrometry by Steinhauser, Matthew L., Lechene, Claude P.

“…•Multi-isotope imaging mass spectrometry (MIMS) merges stable isotope tracers with high-resolution quantitative imaging.•Stable isotope tracers are non-toxic…”
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High-Resolution Multi-Isotope Imaging Mass Spectrometry (MIMS) Imaging Applications in Stem Cell Biology by McMahon, G, Lechene, C P

“…Multi-isotope imaging mass spectrometry (MIMS) allows the measurement of turnover of molecules within intracellular compartments with a spatial resolution down…”
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Glycolysis Supports Calcium Uptake by the Sarcoplasmic Reticulum in Skinned Ventricular Fibres of Mice Deficient in Mitochondrial and Cytosolic Creatine Kinase by Boehm, Ernest, Ventura-Clapier, Renée, Mateo, Philippe, Lechène, Patrick, Veksler, Vladimir

“…E. Boehm, R. Ventura-Clapier, P. Mateo, P. Lechène and V. Veksler. Glycolysis Supports Calcium Uptake by the Sarcoplasmic Reticulum in Skinned Ventricular…”
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J014 Simultaneous recordings of cell shortening and camp or calcium transients reveal differential regulation of cardiac contractility by specific phosphodiesterases by Mika, D, Leroy, J, Lechene, P, Fischmeister, R, Vandecasteele, G

“…Multiple cyclic nucleotide phosphodiesterases (PDEs) belonging to four families (PDE1 to PDE4) hydrolyze cAMP in cardiac cells, but the functional significance…”
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Quasi-simultaneous acquisition of nine secondary ions with seven detectors on NanoSIMS50L: application to biological samples by Guillermier, Christelle, Steinhauser, Matthew L., Lechene, Claude P.

“…We employed a method of electrostatic peak switching allowing for the quasi‐simultaneous measurement of 16O, 18O, C2H, C2D, 12C14N, 13C14N, 12C15N, P, and S…”
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Approaches to increasing analytical throughput of human samples with multi-isotope imaging mass spectrometry by Steinhauser, Matthew L., Guillermier, Christelle, Wang, Mei, Lechene, Claude P.

“…Multi‐isotope imaging mass spectrometry (MIMS) combines stable isotope tracers with the quantitative imaging of NanoSIMS ion microscopy. With extensive safety…”
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The anionic peptide fraction is present on the gallbladder apical epithelium and favours biliary cholesterol absorption by Liguori, F, Domingo, N, Tebala, G, Ripani, C, De Marco, R, Siciliano, M, Attili, A.F, Lairon, D, Lafont, H, de la Porte, P. Lechène, Ginanni Corradini, S

“…Abstract Background/aims We investigated (a) in vitro and in vivo the changes of biliary mass of the anionic peptide fraction, apolipoproteinA-I,…”
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