Search Results - "Lebuhotel, Celine"

Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia by Sugita, Mayumi, Galetto, Roman, Zong, Hongliang, Ewing-Crystal, Nathan, Trujillo-Alonso, Vicenta, Mencia-Trinchant, Nuria, Yip, Winnie, Filipe, Stephanie, Lebuhotel, Celine, Gouble, Agnès, Hassane, Duane C., Smith, Julianne, Roboz, Gail J., Guzman, Monica L.

“…Acute myeloid leukemia (AML) is a disease with high incidence of relapse that is originated and maintained from leukemia stem cells (LSCs). Hematopoietic stem…”
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Multiplex Genome-Edited T-cell Manufacturing Platform for "Off-the-Shelf" Adoptive T-cell Immunotherapies by Poirot, Laurent, Philip, Brian, Schiffer-Mannioui, Cécile, Le Clerre, Diane, Chion-Sotinel, Isabelle, Derniame, Sophie, Potrel, Pierrick, Bas, Cécile, Lemaire, Laetitia, Galetto, Roman, Lebuhotel, Céline, Eyquem, Justin, Cheung, Gordon Weng-Kit, Duclert, Aymeric, Gouble, Agnès, Arnould, Sylvain, Peggs, Karl, Pule, Martin, Scharenberg, Andrew M, Smith, Julianne

“…Adoptive immunotherapy using autologous T cells endowed with chimeric antigen receptors (CAR) has emerged as a powerful means of treating cancer. However, a…”
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Pre-TCRα supports CD3-dependent reactivation and expansion of TCRα-deficient primary human T-cells by Galetto, Román, Lebuhotel, Celine, Poirot, Laurent, Gouble, Agnès, Toribio, Maria L, Smith, Julianne, Scharenberg, Andrew

“…Chimeric antigen receptor technology offers a highly effective means for increasing the anti-tumor effects of autologous adoptive T-cell immunotherapy, and…”
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Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN by Dupuy, Aurélie, Valton, Julien, Leduc, Sophie, Armier, Jacques, Galetto, Roman, Gouble, Agnès, Lebuhotel, Céline, Stary, Anne, Pâques, Frédéric, Duchateau, Philippe, Sarasin, Alain, Daboussi, Fayza

“…Xeroderma pigmentosum group C (XP-C) is a rare human syndrome characterized by hypersensitivity to UV light and a dramatic predisposition to skin neoplasms…”
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Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases by Daboussi, Fayza, Zaslavskiy, Mikhail, Poirot, Laurent, Loperfido, Mariana, Gouble, Agnès, Guyot, Valerie, Leduc, Sophie, Galetto, Roman, Grizot, Sylvestre, Oficjalska, Danusia, Perez, Christophe, Delacôte, Fabien, Dupuy, Aurélie, Chion-Sotinel, Isabelle, Le Clerre, Diane, Lebuhotel, Céline, Danos, Olivier, Lemaire, Frédéric, Oussedik, Kahina, Cédrone, Frédéric, Epinat, Jean-Charles, Smith, Julianne, Yáñez-Muñoz, Rafael J, Dickson, George, Popplewell, Linda, Koo, Taeyoung, VandenDriessche, Thierry, Chuah, Marinee K, Duclert, Aymeric, Duchateau, Philippe, Pâques, Frédéric

“…The ability to specifically engineer the genome of living cells at precise locations using rare-cutting designer endonucleases has broad implications for…”
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Efficient strategies for TALEN-mediated genome editing in mammalian cell lines by Valton, Julien, Cabaniols, Jean-Pierre, Galetto, Romàn, Delacote, Fabien, Duhamel, Marianne, Paris, Sebastien, Blanchard, Domique Alain, Lebuhotel, Céline, Thomas, Séverine, Moriceau, Sandra, Demirdjian, Raffy, Letort, Gil, Jacquet, Adeline, Gariboldi, Annabelle, Rolland, Sandra, Daboussi, Fayza, Juillerat, Alexandre, Bertonati, Claudia, Duclert, Aymeric, Duchateau, Philippe

“…TALEN is one of the most widely used tools in the field of genome editing. It enables gene integration and gene inactivation in a highly efficient and specific…”
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Adoptive immunotherapy of acute myeloid leukemia (AML) with allogenic CAR t-cells targeting CD123 by Galetto, Roman, Lebuhotel, Celine, Francon, Patricia, Gouble, Agnes, Smith, Julianne

“…Abstract only…”
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Down regulation of pRb in cultures of avian neuroretina cells promotes proliferation of reactive Müller-like cells and emergence of retinal stem/progenitors by Marx, Maria, Lebuhotel, Céline, Laugier, Danielle, Chapelle, Audrey, Calothy, Georges, Saule, Simon

“…The aim of this work was to define the role of pRb depletion in the proliferation and differentiation of avian retinoblasts in vitro. For this purpose vectors…”
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Allogenic T-Cells Targeting CD123 for Adoptive Immunotherapy of Acute Myeloid Leukemia (AML) by Galetto, Roman, Lebuhotel, Celine, Gouble, Agnes, Schiffer-Mannioui, Cecile, Smith, Julianne

“…Adoptive immunotherapy using autologous T-cells endowed with chimeric antigen receptors (CARs) has emerged as a promising new approach to treating cancer…”
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Meganuclease-driven targeted integration in CHO-K1 cells for the fast generation of HTS-compatible cell-based assays by Cabaniols, Jean-Pierre, Ouvry, Christine, Lamamy, Véronique, Fery, Isabelle, Craplet, Marie-Laure, Moulharat, Natacha, Guenin, Sophie-Pénélope, Bedut, Stéphane, Nosjean, Olivier, Ferry, Gilles, Devavry, Séverine, Jacqmarcq, Cécile, Lebuhotel, Céline, Mathis, Luc, Delenda, Christophe, Boutin, Jean A, Duchâteau, Philippe, Cogé, Francis, Pâques, Frédéric

“…The development of cell-based assays for high-throughput screening (HTS) approaches often requires the generation of stable transformant cell lines. However,…”
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Pre-T cell receptor for improved expansion of T cells in the absence of TCR alpha by Galetto, Roman, Lebuhotel, Celine, Poirot, Laurent, Mannioui, Cecile Schiffer, Smith, Julianne, Scharenberg, Andrew

“…Recent data have emerged from adoptive T-cell therapies where exogenous expression of a chimeric antigen receptor (CAR) has been shown to confer cancer…”
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Down regulation of pRb in cultures of avian neuroretina cells promotes proliferation of reactive Mueller-like cells and emergence of retinal stem/progenitors by Marx, Maria, Lebuhotel, Celine, Laugier, Danielle, Chapelle, Audrey, Calothy, Georges, Saule, Simon

“…The aim of this work was to define the role of pRb depletion in the proliferation and differentiation of avian retinoblasts in vitro. For this purpose vectors…”
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Pre-TCR[alpha] supports CD3-dependent reactivation and expansion of TCR[alpha]-deficient primary human T-cells by Galetto, Román, Lebuhotel, Celine, Poirot, Laurent, Gouble, Agnès, Toribio, Maria L, Smith, Julianne, Scharenberg, Andrew

“…Chimeric antigen receptor technology offers a highly effective means for increasing the anti-tumor effects of autologous adoptive T-cell immunotherapy, and…”
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Targeted Gene Therapy of Xeroderma Pigmentosum Cells Using Meganuclease and TALEN(TM): e78678 by Dupuy, Aurelie, Valton, Julien, Leduc, Sophie, Armier, Jacques, Galetto, Roman, Gouble, Agnes, Lebuhotel, Celine, Stary, Anne, Paques, Frederic, Duchateau, Philippe

“…Xeroderma pigmentosum group C (XP-C) is a rare human syndrome characterized by hypersensitivity to UV light and a dramatic predisposition to skin neoplasms…”
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419. Allogenic CAR T-Cells Targeting CD123 for Adoptive Immunotherapy of Acute Myeloid Leukemia (AML) by Galetto, Roman, Lebuhotel, Céline, Françon, Patricia, Gouble, Agnès, Smith, Julianne

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397. Allogenic CAR T-Cells Targeting CD123 Effectively Eliminate Myeloid Leukemia Cells by Galetto, Roman, Lebuhotel, Céline, Gouble, Agnès, Bank, Alexander, Roboz, Gail J., Guzman, Monica L., Smith, Julianne

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TCRab Deficient CAR T-Cells Targeting CD123: An Allogeneic Approach of Adoptive Immunotherapy for the Treatment of Acute Myeloid Leukemia (AML) by Galetto, Roman, Lebuhotel, Céline, Gouble, Agnès, Mencia-Trinchant, Nuria, Nicole, Cruz M, Roboz, Gail J., Guzman, Monica L., Smith, Julianne

“…The remissions achieved using autologous T-cells expressing chimeric antigen receptors (CARs) in patients with advanced B cell leukemia and lymphomas have…”
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Abstract 3992: Allogeneic TCRαβ-deficient CAR T-cells targeting CD123 effectively eliminate myeloid leukemia cells in vitro and in vivo PDX mice by Guzman, Monica L., Zong, Hongliang, Sugita, Mayumi, Lara-Martinez, Luis A., Bystrom, Laura M., Cruz, Nicole M., Galetto, Roman, Gouble, Agnès, Lebuhotel, Céline, Bank, Alexander, Smith, Julianne, Roboz, Gail J.

“…Abstract Acute myeloid leukemia (AML) is incurable in the majority of patients. While allogeneic stem cell transplantation remains the most effective therapy…”
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Pre-T cell receptor for improved expansion of TCR alpha disrupted T cells by Galetto, Roman, Lebuhotel, Céline, Poirot, Laurent, Schiffer-Mannioui, Cécile, Arnould, Sylvain, Smith, Julianne, Scharenberg, Andrew

“…Recent data have emerged from adoptive T-cell therapies where exogenous expression of a chimeric antigen receptor (CAR) has been shown to confer cancer…”
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