Search Results - "Lebow, Emily S."
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Impact of TMB/PD-L1 expression and pneumonitis on chemoradiation and durvalumab response in stage III NSCLC
Published in Nature communications (15-07-2023)“…Although concurrent chemoradiation (CRT) and durvalumab consolidation has become a standard treatment for stage III non-small cell lung cancer (NSCLC),…”
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Multi-institutional analysis of aneuploidy and outcomes to chemoradiation and durvalumab in stage III non-small cell lung cancer
Published in Journal for immunotherapy of cancer (01-11-2023)“…There is a need to identify predictive biomarkers to guide treatment strategies in stage III non-small cell lung cancer (NSCLCs). In this multi-institutional…”
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Symptomatic Necrosis With Antibody-Drug Conjugates and Concurrent Stereotactic Radiotherapy for Brain Metastases
Published in JAMA oncology (01-12-2023)Get more information
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Stereotactic body radiation therapy for sarcoma pulmonary metastases
Published in Radiotherapy and oncology (01-10-2023)“…Stereotactic body radiation therapy (SBRT) is standard for patients with inoperable early-stage NSCLC. We hypothesized that SBRT for sarcoma pulmonary…”
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Characterization of Central Nervous System Clinico-Genomic Outcomes in ALK-Positive Non-Small Cell Lung Cancer Patients with Brain Metastases Treated with Alectinib
Published in Lung cancer (Amsterdam, Netherlands) (01-04-2023)“…•Extensive series of alectinib-treated lung cancer brain metastases with detailed lesion-level data and genomic correlates.•No differences in clinical outcomes…”
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Clinical utility of next-generation sequencing-based ctDNA testing for common and novel ALK fusions
Published in Lung cancer (Amsterdam, Netherlands) (01-09-2021)“…•Liquid biopsy for plasma ctDNA NGS is capable of partner agnostic detection of ALK fusions.•A subset of patients can be matched to ALK-directed therapy based…”
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Modelling of late side-effects following cranial proton beam therapy
Published in Radiotherapy and oncology (01-04-2021)“…•Availability of proton therapy is limited requiring individual treatment selection strategies.•Selection strategies may be based on NTCP models, some of which…”
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Early experience with hippocampal avoidance whole brain radiation therapy and simultaneous integrated boost for brain metastases
Published in Journal of neuro-oncology (01-05-2020)“…Purpose Cranial irradiation results in cognitive decline, which is hypothesized to be partially attributable to hippocampal injury and stem cell loss. Recent…”
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Proton therapy for head and neck paragangliomas: A single institutional experience
Published in Head & neck (01-04-2020)“…Background Although slow growing, head and neck paragangliomas (HNPG) can cause significant morbidity. We evaluated the efficacy of proton therapy in the…”
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Radiation Therapy for IDH-Mutant Grade 2 and Grade 3 Diffuse Glioma: An ASTRO Clinical Practice Guideline
Published in Practical Radiation Oncology (01-09-2022)“…This guideline provides evidence-based recommendations for adults with isocitrate dehydrogenase (IDH)–mutant grade 2 and grade 3 diffuse glioma, as classified…”
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ctDNA-based detection of molecular residual disease in stage I-III non-small cell lung cancer patients treated with definitive radiotherapy
Published in Frontiers in oncology (19-09-2023)“…Sensitive and reliable biomarkers for early detection of recurrence are needed to improve post-definitive radiation risk stratification, disease management,…”
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Tumor volume as a predictor of cell free DNA mutation detection in advanced non-small cell lung cancer
Published in Translational lung cancer research (01-08-2022)Get full text
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Analysis of Tumor Mutational Burden, Progression-Free Survival, and Local-Regional Control in Patents with Locally Advanced Non-Small Cell Lung Cancer Treated With Chemoradiation and Durvalumab
Published in JAMA network open (05-01-2023)“…The addition of consolidative durvalumab to chemoradiation has improved disease control and survival in locally advanced non-small cell lung cancer (NSCLC)…”
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Analysis of Tumor Mutational Burden, Progression-Free Survival, and Local-Regional Control in Patients with Locally Advanced Non–Small Cell Lung Cancer Treated With Chemoradiation and Durvalumab
Published in JAMA network open (03-01-2023)“…Importance The addition of consolidative durvalumab to chemoradiation has improved disease control and survival in locally advanced non–small cell lung cancer…”
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Early Circulating Tumor DNA Shedding Kinetics for Prediction of Platinum Sensitivity in Patients With Small Cell Lung Cancer
Published in JCO precision oncology (01-09-2024)“…Small cell lung cancer (SCLC) is characterized by rapid progression after platinum resistance. Circulating tumor (ctDNA) dynamics early in treatment may help…”
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"Big Boom" (4 Gy x 1) Radiation Treatment (RT) Versus "Big Boom" (2 Gy x 2) for Non-Hodgkin Lymphoma (NHL)
Published in Blood (15-11-2022)Get full text
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Overall survival with circulating tumor DNA-guided therapy in advanced non-small-cell lung cancer
Published in Nature medicine (01-11-2022)“…Circulating tumor DNA (ctDNA) sequencing guides therapy decisions but has been studied mostly in small cohorts without sufficient follow-up to determine its…”
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Primary Hepatic Lymphoma: Role of Low-Dose Radiotherapy at a Single Institution with Genetic Characterization and Paired Literature Review
Published in Blood (15-11-2022)Get full text
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Genetic Alterations of Crebbp Are Associated with Radiosensitivity in Follicular Lymphoma
Published in Blood (15-11-2022)Get full text
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