Search Results - "Leblond, M"
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1
Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies
Published in Gut (01-03-2022)“…In this study, we determined whether ( ) infection dampens the efficacy of cancer immunotherapies. Using mouse models, we evaluated whether immune checkpoint…”
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2
M2 macrophages are more resistant than M1 macrophages following radiation therapy in the context of glioblastoma
Published in Oncotarget (22-09-2017)“…In some highly inflammatory tumors, such as glioblastoma (GB), macrophages (MΦ) represent the most abundant population of reactive cells. MΦ, initially denoted…”
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3
Avoidance of roads by large herbivores and its relation to disturbance intensity
Published in Journal of zoology (1987) (01-01-2013)“…Avoidance of roads has been demonstrated for many animal species, but little is known about the relationship between anthropogenic disturbance levels and the…”
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4
Hypoxia induces macrophage polarization and re-education toward an M2 phenotype in U87 and U251 glioblastoma models
Published in Oncoimmunology (01-01-2016)“…Hypoxia is a common feature of solid tumors, particularly in glioblastoma (GBM), and known to be a poor prognosis factor in GBM patients. The growth of GBM is…”
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Impact of Hypoxia on Carbon Ion Therapy in Glioblastoma Cells: Modulation by LET and Hypoxia-Dependent Genes
Published in Cancers (23-07-2020)“…Tumor hypoxia is known to limit the efficacy of ionizing radiations, a concept called oxygen enhancement ratio (OER). OER depends on physical factors such as…”
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6
Climate-sensitive forecasts of marked short-term and long-term changes in the distributions or abundances of Northwestern boreal landbirds
Published in Climate change ecology (01-07-2024)“…•Boreal birds will experience northward shifts as temperatures become warmer.•As new analytical methods and forecasting tools arise, decision-makers are better…”
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7
Tumor-Associated Macrophages in Bladder Cancer: Biological Role, Impact on Therapeutic Response and Perspectives for Immunotherapy
Published in Cancers (21-09-2021)“…Tumor-associated macrophages (TAMs) are one of the most abundant infiltrating immune cells of solid tumors. Despite their possible dual role, i.e., pro- or…”
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c‐Maf enforces cytokine production and promotes memory‐like responses in mouse and human type 2 innate lymphoid cells
Published in The EMBO journal (14-06-2022)“…Group‐2 innate lymphoid cells (ILC2s), which are involved in type 2 inflammatory diseases such as allergy, can exhibit immunological memory, but the basis of…”
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9
Maf deficiency in T cells dysregulates T reg - T H 17 balance leading to spontaneous colitis
Published in Scientific reports (01-12-2019)“…The maintenance of homeostasis in the gut is a major challenge for the immune system. Here we demonstrate that the transcription factor MAF plays a central…”
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10
Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustion
Published in Nature immunology (01-10-2023)“…Persistent exposure to antigen during chronic infection or cancer renders T cells dysfunctional. The molecular mechanisms regulating this state of exhaustion…”
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11
Polymorphism of Chiral Thioester Studied by Dielectric Spectroscopy
Published in Acta physica Polonica, A (01-12-2013)“…(S)-(+)-4′-[(4-(1-methylheptyloxycarbonylphenyl) thiocarbonylphenyl]-decyloxybenzoate (in short10.OPOSMH) was studied by complementary methods. The substance…”
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12
Development of Traceable Mouse Models of Advanced and Metastatic Bladder Cancer
Published in Cancers (17-06-2024)“…Bladder cancer (BC) is the fourth most common cancer in men, with a poor patient prognosis for advanced disease. The poor survival of patients with…”
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13
Linear and non-linear dielectric properties of a short-pitch ferroelectric liquid crystal stabilized by a polymer network
Published in The European physical journal. E, Soft matter and biological physics (01-12-2010)“… Linear and non-linear dielectric measurements were carried out on a ferroelectric liquid crystal stabilized by an anisotropic polymer network. The…”
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14
Maf deficiency in T cells dysregulates Treg - TH17 balance leading to spontaneous colitis
Published in Scientific reports (16-04-2019)“…The maintenance of homeostasis in the gut is a major challenge for the immune system. Here we demonstrate that the transcription factor MAF plays a central…”
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15
Immuno-Transcriptomic Profiling of Blood and Tumor Tissue Identifies Gene Signatures Associated with Immunotherapy Response in Metastatic Bladder Cancer
Published in Cancers (01-01-2024)“…Blood-based biomarkers represent ideal candidates for the development of non-invasive immuno-oncology-based assays. However, to date, no blood biomarker has…”
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16
Rearrangements at the 11p15 locus and overexpression of insulin-like growth factor-II gene in sporadic adrenocortical tumors
Published in The journal of clinical endocrinology and metabolism (01-06-1994)“…Little is known about the pathophysiology of sporadic adrenocortical tumors in adults. Because loss of heterozygosity at the 11p15 locus has been described in…”
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17
Direct Characterization of Kerogen by X-ray and Solid-State 13C Nuclear Magnetic Resonance Methods
Published in Energy & fuels (16-05-2007)“…A combination of solid-state 13C NMR, X-ray photoelectron spectroscopy (XPS) and sulfur X-ray absorption near edge structure (S-XANES) techniques are used to…”
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18
Angiopoietin-2 Combined with Radiochemotherapy Impedes Glioblastoma Recurrence by Acting in an Autocrine and Paracrine Manner: A Preclinical Study
Published in Cancers (30-11-2020)“…(1) We wanted to assess the impact of Ang2 in RCT-induced changes in the environment of glioblastoma. (2) The effect of Ang2 overexpression in tumor cells was…”
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Carbogen-induced increases in tumor oxygenation depend on the vascular status of the tumor: A multiparametric MRI study in two rat glioblastoma models
Published in Journal of cerebral blood flow and metabolism (01-06-2017)“…The alleviation of hypoxia in glioblastoma with carbogen to improve treatment has met with limited success. Our hypothesis is that the eventual benefits of…”
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Direct Characterization of Kerogen by X-ray and Solid-State [superscript 13]C Nuclear Magnetic Resonance Methods
Published in Energy & fuels (12-06-2008)“…A combination of solid-state {sup 13}C NMR, X-ray photoelectron spectroscopy (XPS) and sulfur X-ray absorption near edge structure (S-XANES) techniques are…”
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