Search Results - "Lebina, Limakatso"
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SARS-CoV-2 incidence, transmission, and reinfection in a rural and an urban setting: results of the PHIRST-C cohort study, South Africa, 2020–21
Published in The Lancet infectious diseases (01-06-2022)“…By August, 2021, South Africa had been affected by three waves of SARS-CoV-2; the second associated with the beta variant and the third with the delta variant…”
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SARS-CoV-2 Seroprevalence in a Rural and Urban Household Cohort during First and Second Waves of Infections, South Africa, July 2020–March 2021
Published in Emerging infectious diseases (01-12-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections may be underestimated because of limited access to testing. We measured SARS-CoV-2…”
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A clinical score for identifying active tuberculosis while awaiting microbiological results: Development and validation of a multivariable prediction model in sub-Saharan Africa
Published in PLoS medicine (10-11-2020)“…In highly resource-limited settings, many clinics lack same-day microbiological testing for active tuberculosis (TB). In these contexts, risk of pretreatment…”
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Rapidly shifting immunologic landscape and severity of SARS-CoV-2 in the Omicron era in South Africa
Published in Nature communications (16-01-2023)“…South Africa was among the first countries to detect the SARS-CoV-2 Omicron variant. However, the size of its Omicron BA.1 and BA.2 subvariants (BA.1/2) wave…”
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The cost and cost implications of implementing the integrated chronic disease management model in South Africa
Published in PloS one (26-06-2020)“…Background A cost analysis of implementation of interventions informs budgeting and economic evaluations. Objective To estimate the cost of implementing the…”
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Process evaluation of implementation fidelity of the integrated chronic disease management model in two districts, South Africa
Published in BMC health services research (16-12-2019)“…The Integrated Chronic Disease Management (ICDM) model has been implemented in South Africa to enhance quality of clinical services in Primary Healthcare (PHC)…”
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Asymptomatic transmission and high community burden of seasonal influenza in an urban and a rural community in South Africa, 2017–18 (PHIRST): a population cohort study
Published in The Lancet global health (01-06-2021)“…Data on influenza community burden and transmission are important to plan interventions especially in resource-limited settings. However, data are limited,…”
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Contact tracing versus facility-based screening for active TB case finding in rural South Africa: A pragmatic cluster-randomized trial (Kharitode TB)
Published in PLoS medicine (30-04-2019)“…There is a dearth of comparative effectiveness research examining the implementation of different strategies for active tuberculosis (TB) case finding,…”
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A mixed methods approach to exploring the moderating factors of implementation fidelity of the integrated chronic disease management model in South Africa
Published in BMC health services research (06-07-2020)“…Chronic care models like the Integrated Chronic Disease Management (ICDM) model strive to improve the efficiency and quality of care for patients with chronic…”
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Process evaluation of fidelity and costs of implementing the Integrated Chronic Disease Management model in South Africa: mixed methods study protocol
Published in BMJ open (01-06-2019)“…IntroductionThe South African Department of Health has developed and implemented the Integrated Chronic Disease Management (ICDM) model to respond to the…”
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Prevalence and risk factors for latent tuberculosis infection among household contacts of index cases in two South African provinces: Analysis of baseline data from a cluster-randomised trial
Published in PloS one (17-03-2020)“…Household contacts of patients with active pulmonary tuberculosis (TB) often have latent TB infection, and are at risk of progression to disease. We set out to…”
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Incidence and transmission of respiratory syncytial virus in urban and rural South Africa, 2017-2018
Published in Nature communications (02-01-2024)“…Data on respiratory syncytial virus (RSV) incidence and household transmission are limited. To describe RSV incidence and transmission, we conducted a…”
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Healthcare utilization during the first two waves of the COVID-19 epidemic in South Africa: A cross-sectional household survey
Published in PloS one (25-08-2023)“…Healthcare utilization surveys contextualize facility-based surveillance data for burden estimates. We describe healthcare utilization in the catchment areas…”
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Rapid intra-host diversification and evolution of SARS-CoV-2 in advanced HIV infection
Published in Nature communications (22-08-2024)“…Previous studies have linked the evolution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genetic variants to persistent infections in people…”
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SARS-CoV-2 Seroprevalence after Third Wave of Infections, South Africa
Published in Emerging infectious diseases (01-05-2022)“…By November 2021, after the third wave of severe acute respiratory syndrome coronavirus 2 infections in South Africa, seroprevalence was 60% in a rural…”
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Evaluating systematic targeted universal testing for tuberculosis in primary care clinics of South Africa: A cluster-randomized trial (The TUTT Trial)
Published in PLoS medicine (22-05-2023)“…The World Health Organization (WHO) recommends systematic symptom screening for tuberculosis (TB). However, TB prevalence surveys suggest that this strategy…”
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Ethical Implications of eHealth Tools for Delivering STI/HIV Laboratory Results and Partner Notifications
Published in Current HIV/AIDS reports (01-06-2021)“…Purpose of Review eHealth tools are increasingly utilized for communication with patients. Although efficacious and cost-effective, these tools face several…”
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Correction: Transient increased risk of influenza infection following RSV infection in South Africa: findings from the PHIRST study, South Africa, 2016-2018
Published in BMC medicine (21-03-2024)“…School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa Jackie Kleynhans, Stefano Tempia & Cheryl…”
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Incidence and Transmission Dynamics of Bordetella pertussis Infection in Rural and Urban Communities, South Africa, 2016‒2018
Published in Emerging infectious diseases (01-02-2023)“…We conducted 3 prospective cohort studies (2016-2018), enrolling persons from 2 communities in South Africa. Nasopharyngeal swab specimens were collected twice…”
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Transient increased risk of influenza infection following RSV infection in South Africa: findings from the PHIRST study, South Africa, 2016-2018
Published in BMC medicine (15-11-2023)“…Large-scale prevention of respiratory syncytial virus (RSV) infection may have ecological consequences for co-circulating pathogens, including influenza. We…”
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