Search Results - "Leber, Amy"

Maternal and congenital human cytomegalovirus infection: laboratory testing for detection and diagnosis by Leber, Amy L

“…Human cytomegalovirus (CMV) is the leading cause of congenital infection worldwide and the most common cause of non-genetic sensorineural hearing loss. As…”
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The Hidden Crisis in the Times of COVID-19: Critical Shortages of Medical Laboratory Professionals in Clinical Microbiology by Leber, Amy L, Peterson, Ellena, Dien Bard, Jennifer

“…The COVID pandemic has put a spotlight on laboratory medicine, showcasing how vital diagnostic testing is for society and the health care system. It has also…”
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Mutation-Specific SARS-CoV-2 PCR Screen: Rapid and Accurate Detection of Variants of Concern and the Identification of a Newly Emerging Variant with Spike L452R Mutation by Wang, Huanyu, Jean, Sophonie, Eltringham, Richard, Madison, John, Snyder, Pamela, Tu, Huolin, Jones, Daniel M, Leber, Amy L

“…The emergence of more transmissible and/or more virulent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC) has triggered…”
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Multicenter Evaluation of BioFire FilmArray Respiratory Panel 2 for Detection of Viruses and Bacteria in Nasopharyngeal Swab Samples by Leber, Amy L, Everhart, Kathy, Daly, Judy A, Hopper, Aubrey, Harrington, Amanda, Schreckenberger, Paul, McKinley, Kathleen, Jones, Matthew, Holmberg, Kristen, Kensinger, Bart

“…The FilmArray Respiratory Panel 2 (RP2) is a multiplex diagnostic test for the simultaneous and rapid (∼45-min) detection of 22 pathogens directly from…”
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Reduced sensitivity of a multiplex commercial respiratory panel for detection of Mycoplasma pneumoniae is due to specimen type by Leber, Amy L, Oyeniran, Sophonie J, Wang, Huanyu

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Multicenter Evaluation of BioFire FilmArray Meningitis/Encephalitis Panel for Detection of Bacteria, Viruses, and Yeast in Cerebrospinal Fluid Specimens by Leber, Amy L, Everhart, Kathy, Balada-Llasat, Joan-Miquel, Cullison, Jillian, Daly, Judy, Holt, Sarah, Lephart, Paul, Salimnia, Hossein, Schreckenberger, Paul C, DesJarlais, Sharon, Reed, Sharon L, Chapin, Kimberle C, LeBlanc, Lindsay, Johnson, J Kristie, Soliven, Nicole L, Carroll, Karen C, Miller, Jo-Anne, Dien Bard, Jennifer, Mestas, Javier, Bankowski, Matthew, Enomoto, Tori, Hemmert, Andrew C, Bourzac, Kevin M

“…Rapid diagnosis and treatment of infectious meningitis and encephalitis are critical to minimize morbidity and mortality. Comprehensive testing of…”
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Diagnosis of Clostridium difficile Infections in Children by Antonara, Stella, Leber, Amy L

“…The detection and diagnosis of Clostridium difficile infection in pediatric populations have some unique considerations in comparison to testing in adults. The…”
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Differences in SARS-CoV-2 Clinical Manifestations and Disease Severity in Children and Adolescents by Infecting Variant by Quintero, Ana Maria, Eisner, Mariah, Sayegh, Rouba, Wright, Tori, Ramilo, Octavio, Leber, Amy L, Wang, Huanyu, Mejias, Asuncion

“…Since the COVID-19 pandemic began, different SARS-CoV-2 variants have been identified and associated with higher transmissibility than the ancestral nonvariant…”
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Clinical and molecular characteristics of the 2022 Enterovirus-D68 outbreak among hospitalized children, Ohio, USA by Cao, Raquel Giacomelli, Mejias, Asuncion, Leber, Amy L, Wang, Huanyu

“…Enterovirus-D68 (EV-D68) has appeared biennially in the United States following the 2014 outbreak. It has gained epidemiologic and clinical relevance and was…”
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Multicenter Evaluation of the DiaSorin Molecular Simplexa Congenital CMV Direct PCR Test on Neonatal Saliva and Urine Specimens by Dunn, James J, Selvarangan, Rangaraj, Maggert, Kevin, Young, Stephen, Leber, Amy L

“…Cytomegalovirus (CMV) is the most common virus associated with congenital infection worldwide and is a major cause of sensorineural hearing loss (SNHL) and…”
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Multicenter Evaluation of the QIAstat-Dx Respiratory Panel for Detection of Viruses and Bacteria in Nasopharyngeal Swab Specimens by Leber, Amy L, Lisby, Jan Gorm, Hansen, Glen, Relich, Ryan F, Schneider, Uffe Vest, Granato, Paul, Young, Stephen, Pareja, Josep, Hannet, Irene

“…The QIAstat-Dx Respiratory Panel (QIAstat-Dx RP) is a multiplex diagnostic test for the qualitative detection of 20 pathogens directly from nasopharyngeal swab…”
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Performance comparison of three commercial tests for the detection of SARS-CoV-2 antibodies in a common set of pediatric samples by Oyeniran, Sophonie J, Wang, Huanyu, Everhart, Kathy, Mack, Kathy, Harvey, Kevin, Leber, Amy L

“…Serologic testing for SARS CoV-2 is useful for detection of past infection and assisting in diagnosis of post-COVID-19 syndromes such as MIS-C. Immune…”
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Staphylococcus aureus and methicillin resistance detection directly from pediatric samples using PCR assays with differential cycle threshold values for corroboration of methicillin resistance by Wang, Huanyu, Hecht, Shaina, Kline, David, Leber, Amy L.

“…Staphylococcus aureus is a major human pathogen, causing a variety of nosocomial and community-acquired infections. While S. aureus usually grows well, there…”
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Multicenter Evaluation of the BioFire FilmArray Pneumonia/Pneumonia Plus Panel for Detection and Quantification of Agents of Lower Respiratory Tract Infection by Murphy, Caitlin N, Fowler, Randal, Balada-Llasat, Joan Miquel, Carroll, Amanda, Stone, Hanna, Akerele, Oluseun, Buchan, Blake, Windham, Sam, Hopp, Amanda, Ronen, Shira, Relich, Ryan F, Buckner, Rebecca, Warren, Del A, Humphries, Romney, Campeau, Shelly, Huse, Holly, Chandrasekaran, Suki, Leber, Amy, Everhart, Kathy, Harrington, Amanda, Kwong, Christina, Bonwit, Andrew, Dien Bard, Jennifer, Naccache, Samia, Zimmerman, Cynthia, Jones, Barbara, Rindlisbacher, Cory, Buccambuso, Maggie, Clark, Angela, Rogatcheva, Margarita, Graue, Corrin, Bourzac, Kevin M

“…The ability to provide timely identification of the causative agents of lower respiratory tract infections can promote better patient outcomes and support…”
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A Hypothesis-Generating Prospective Longitudinal Study to Assess the Relative Contribution of Common Respiratory Viruses to Severe Lower Respiratory Infections in Young Children by Ben-Shimol, Shalom, Ramilo, Octavio, Leber, Amy L., van der Beek, Bart Adriaan, Everhart, Kathy, Mertz, Sara, Mejias, Asuncion, Dagan, Ron

“…Respiratory viruses such as respiratory syncytial virus (RSV), influenza, parainfluenza and human metapneumovirus are well-established etiologies of acute…”
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Evaluation of the Cepheid Xpert SA Nasal Complete for direct detection of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus in nasal swabs from pediatric patients by Wang, Huanyu, Salamon, Doug, Jean, Sophonie, Leber, Amy L.

“…Nasal carriers of Staphylococcus aureus (SA) are at increased risk for health-care associated infections with this organism. Timely detection of SA and…”
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Respiratory syncytial virus and SARS‐CoV‐2 coinfections in children by Halabi, Katia C., Wang, Huanyu, Leber, Amy L., Sánchez, Pablo J., Ramilo, Octavio, Mejias, Asuncion

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Detection of human herpesvirus 6 in pediatric CSF samples: causing disease or incidental distraction? by Wang, Huanyu, Tomatis-Souverbielle, Cristina, Everhart, Kathy, Oyeniran, Sophonie J., Leber, Amy L.

“…Interpretation of human herpesvirus type 6 (HHV6) detection in the cerebrospinal fluid (CSF) of children can be complex; the virus can cause acute infection,…”
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Shedding of measles vaccine RNA in children after receiving measles, mumps and rubella vaccination by Washam, Matthew C., Leber, Amy L., Oyeniran, Sophonie J., Everhart, Kathy, Wang, Huanyu

“…•Shedding of measles vaccine RNA is not uncommon and vaccine RNA can be detected in the nasopharyngeal samples up to 29 days post MMR.•The amount of vaccine…”
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Macrolide-Resistant Mycoplasma pneumoniae Infections in Children, Ohio, USA by Lanata, Mariana M, Wang, Huanyu, Everhart, Kathy, Moore-Clingenpeel, Melisa, Ramilo, Octavio, Leber, Amy

“…Emergence of macrolide-resistant Mycoplasma pneumoniae (MRMp) challenges empiric macrolide therapy. Our goal was to determine MRMp rates and define…”
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