Search Results - "Lebedev, L. R"

Production methods and properties of virus-like particles of Saccharomyces cerevisiae yeast killer strain by Shevchenko, Z. A, Lebedev, L. R, Klimenko, V. P, Masycheva, V. I, Gamaley, S. G, Bateneva, A. V, Danilenko, E. D, Ilyasov, E. A, Azaev, M. Sh, Zaytsev, B. N

“…Based on the technology for producting virus-like particles of a killer strain of Saccharomyces cerevisiae Y-448 yeast, which includes stages of extraction,…”
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Stimulating effect of double-stranded yeast RNA on the activity of interferon system genes by Bateneva, A. V., Gamaley, S. G., Danilenko, E. D., Lebedev, R. L.

“…Influence of double-stranded RNA (dsRNA) from Saccharomyces cerevisiae yeast upon expression levels of the macrophage genes encoding TLR3 receptor, interferons…”
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Pharmacokinetics and Antitumor Effects of the Drug Containing TNF-α in Nanoparticles by Gamaley, S. G, Bateneva, A. V, Sysoeva, G. M, Danilenko, E. D, Lebedev, L. R, Masycheva, V. I

“…Antitumor activity of TNF-α incorporated in nanoparticles (VLP-TNF-α) and dynamics of its accumulation and elimination from the blood and tumor tissue were…”
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3D structure modeling of complexes formed by CrmB TNF-binding proteins of Variola and cowpox viruses with murine and human TNFs by Nepomnyashchikh, T. S, Antonets, D. V, Lebedev, L. R, Gileva, I. P, Shchelkunov, S. N

“…Orthopoxviral genomes bear genes for a series of homologous secreted proteins binding tumor necrosis factor (TNF). Orthopoxvirus species have different sets of…”
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Study on the Methods for Synthesis of GM-CSF Conjugates with Alendronic Acid by Esina, T. I., Volosnikova, E. A., Lebedev, L. R., Kochneva, G. V., Grazhdantseva, A. A.

“…— In order to develop a target drug we studied the process of conjugation of recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) and…”
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INDUCTION OF APOPTOSIS IN B16 MELANOMA CELLS UNDER THE ACTION OF DRUG CONTAINING TUMOR NECROSIS FACTOR ALPHA AS A PART OF VIRUS-LIKE PARTICLES IN VITRO by Vyazovaya, E. A., Lebedev, L. R., Danilenko, E. D.

“…Aim: to evaluate the antitumor activity of the drug containing TNF-alpha and high-polymer double-stranded RNA (dsRNA) in the composition of virus-like…”
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Development of technology for purification of plasmid DNAs for pharmaceutical purposes by Volosnikova, E. A, Akulova, N. I, Gogina, Ya. S, Levagina, G. M, Mikhailova, V. K, Lebedev, L. R, Podgornyi, V. F, Telegina, Yu. V

“…Optimization of the stage of fractioning of nucleotide material has been performed, and a technology for purification and obtaining of plasmid DNAs for…”
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EFFECT OF THE MYCELIUM EXTRACT FROM DUDDINGTONIA FLAGRANS FUNGUS ON SUBCUTANEOUS XENOGRAFT OF HUMAN C33a CERVICAL CARCINOMA CELLS by Solovieva, O. I., Zavjalov, E. L., Teplyakova, T. V., Lebedev, L. R., Razumov, I A.

“…The purpose of the study was to analyze the antitumor effects of the extract of mycelium from Duddingtonia flagrans (strain F-882) on xenografts of human C33a…”
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Results of phase I clinical trials of a combined vaccine against HIV-1 based on synthetic polyepitope immunogens by Karpenko, L. I., Bazhan, S. I., Bogryantseva, M. P., Ryndyuk, N. N., Ginko, Z. I., Kuzubov, V. I., Lebedev, L. R., Kaplina, O. N., Reguzova, A. Yu, Ryzhikov, A. B., Usova, S. V., Oreshkova, S. F., Nechaeva, E. A., Danilenko, E. D., Ilyichev, A. A.

“…The CombiHIVvac candidate vaccine against HIV-1/AIDS containing two synthetic polyepitope immunogens such as TBI and TCI to stimulate the humoral and cellular…”
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An antitumor osteotropic agent based on tumor necrosis factor by Lebedev, L. R., Danilenko, E. D., Telegina, Yu. V., Zaitsev, B. N.

“…An osteotropic agent based on the human recombinant tumor necrosis factor alpha (TNF-alpha) has been designed for treatment of bone metastases. It represents a…”
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STUDY OF TECHNOLOGICAL PROPERTIES OF MILK-CLOTTING ENZYME FROM IRPEX LACTEUS (Irpex lacteus (Fr.) Fr.) by Lebedev, L. R., Kosogova, Т. А., Teplyakova, Т. V., Kriger, A. V., Elchaninov, V. V., Belov, А. N., Коval', А. D.

“…Due to the scarcity of natural rennet, in this study we have considered an option of using in cheesemaking a milk-clotting enzyme produced by the Irpex lacteus…”
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Expression of genes for orthopoxviral TNF-binding proteins in insect cells and investigation of the recombinant TNF-binding proteins by Gileva, I P, Ryazankin, I A, Nepomnyashchikh, T S, Totmenin, A V, Maxutov, Z A, Lebedev, L R, Afinogenova, G N, Pustoshilova, N M, Shchelkunov, S N

“…Genes for TNF-binding proteins (CrmBs) of the variola virus (VARV), monkeypox virus (MPXV) or cowpox virus (CPXV) were isolated by PCR from viral genomes and…”
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Experimental Molecular Design of Combined Vaccines by Lebedev, L R, Goncharova, E P, Sizov, A A, Bulychev, L E, Odegov, A M, Ryzhikov, A B

“…A method was elaborated to construct combined artificial immunogens simulating virus particles. The gist was exposing protein antigenic determinants of one…”
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Construction of virus-like particles exposing HIV-1 epitopes by Lebedev, L. R., Karpenko, L. I., Poryvaeva, V. A., Azaev, M. Sh, Ryabchikova, E. I., Gileva, I. P., Il’ichev, A. A.

“…An original method was elaborated to construct artificial immunogens in the form of spherical particles with yeast dsRNA in the center and hybrid proteins…”
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Comparative analysis using a mouse model of the immunogenicity of artificial VLP and attenuated Salmonella strain carrying a DNA-vaccine encoding HIV-1 polyepitope CTL-immunogen by Karpenko, Larisa I, Nekrasova, Nadezhda A, Ilyichev, Alexander A, Lebedev, Leonid R, Ignatyev, George M, Agafonov, Alexander P, Zaitsev, Boris N, Belavin, Pavel A, Seregin, Sergei V, Danilyuk, Nadezhda K, Babkina, Irina N, Bazhan, Sergei I

“…Two systems have been examined for delivery of DNA-vaccine encoding a HIV-1 polyepitope CTL-immunogen (TCI). One is intended for i.m. injection and is in the…”
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Neutralizing single-chain antibodies against the tick-borne encephalitis virus by Levanov, L. N., Matveev, L. E., Yun, T. E., Goncharova, E. P., Lebedev, L. R., Shvalov, A. N., Ryzhykov, A. B., Baikov, I. K., Matveeva, V. A., Rikhter, V. A., Tikunova, N. V.

“…A recombinant pSC13D6 plasmid DNA was constructed based on cDNA fragments of genes encoding variable domains of heavy and light chains of the MKA13D6…”
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Designing and engineering of DNA-vaccine construction encoding multiple CTL-epitopes of major HIV-1 antigens by Bazhan, Sergei I, Belavin, Pavel A, Seregin, Sergei V, Danilyuk, Nadezhda K, Babkina, Irina N, Karpenko, Larisa I, Nekrasova, Nadezhda A, Lebedev, Leonid R, Ignatyev, George M, Agafonov, Alexander P, Poryvaeva, Vera A, Aborneva, Irina V, Ilyichev, Alexander A

“…A synthetic T cell immunogen (TCI) has been designed as a candidate DNA-based vaccine against Human immunodeficiency virus (HIV)-1 using cytotoxic T…”
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Humoral immune response of BALB/c mice immunized with chimer HBcAg proteins carrying the epitopes of surface hepatic B virus protein by Veremeĭko, T A, Lebedev, L R, Chikaev, N A, Il'ichev, A A, Karpenko, L I

“…Chimeric HBcAg proteins carrying epitopes from surface hepatitis B virus (HBV) protein (regions 137-147 a.o. HBsAg, 27-37 a.a. region preS1 and 131-145 a.a…”
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Comparison of the Interferon γ-Binding Proteins of the Variola and Monkeypox Viruses by Nepomnyashchikh, T. S., Lebedev, L. R., Ryazankin, I. A., Pozdnyakov, S. G., Gileva, I. P., Shchelkunov, S. N.

“…PCR was used to amplify DNA fragments containing the genes for interferon γ (IFNγ)-binding proteins (IFNγBPs) of the variola virus (VARV) and monkeypox virus…”
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