Search Results - "Lebedev, Jenna N."
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Characterization and refinement of monoclonal anti‐human globulins that lack reactivity with human IgG4
Published in Transfusion (Philadelphia, Pa.) (01-05-2020)“…BACKGROUND Anti–red blood cell (RBC) alloantibodies consisting of only the immunoglobulin G (IgG) 4 subtype are typically considered clinically insignificant…”
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IgG3 anti‐Kell allotypic variation results in differential antigen binding and phagocytosis
Published in Transfusion (Philadelphia, Pa.) (01-04-2020)“…BACKGROUND Human immunoglobulin G (hIgG) includes four different subtypes (IgG1, IgG2, IgG3, and IgG4). Due to genetic variations, each IgG subtype contains…”
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Serological blind spots for variants of human IgG3 and IgG4 by a commonly used anti-immunoglobulin reagent
Published in Transfusion (Philadelphia, Pa.) (01-12-2016)“…BACKGROUND Human immunoglobulin G (IgG) includes four different subtypes (IgG1, IgG2, IgG3, and IgG4), and it is also now appreciated that there are genetic…”
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Passively transferred IgG enhances humoral immunity to a red blood cell alloantigen in mice
Published in Blood advances (14-04-2020)“…Antibodies are typically thought of as the endpoint of humoral immunity that occur as the result of an adaptive immune response. However, affinity-matured…”
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Errors in data interpretation from genetic variation of human analytes
Published in JCI insight (06-07-2017)“…In recent years, the extent of our vulnerability to misinterpretation due to poorly characterized reagents has become an issue of great concern. Antibody…”
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Serological blind spots for variants of human I g G 3 and I g G 4 by a commonly used anti‐immunoglobulin reagent
Published in Transfusion (Philadelphia, Pa.) (01-12-2016)Get full text
Journal Article