Search Results - "Leaver, J"

Spatially resolved photoluminescence analysis of the role of Se in CdSexTe1−x thin films by Bowman, A. R., Leaver, J. F., Frohna, K., Stranks, S. D., Tagliabue, G., Major, J. D.

“…Evidence from cross-sectional electron microscopy has previously shown that Se passivates defects in CdSe x Te 1−x solar cells, and that this is the reason for…”
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Functional desaturase Fads1 (Δ5) and Fads2 (Δ6) orthologues evolved before the origin of jawed vertebrates by Castro, Luís Filipe Costa, Monroig, Óscar, Leaver, Michael J, Wilson, Jonathan, Cunha, Isabel, Tocher, Douglas R

“…Long-chain polyunsaturated fatty acids (LC-PUFAs) such as arachidonic (ARA), eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids are essential components of…”
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Synthesis and Biological Activity of Sterol 14α-Demethylase and Sterol C24-Methyltransferase Inhibitors by Leaver, David J

“…Sterol 14α-demethylase (SDM) is essential for sterol biosynthesis and is the primary molecular target for clinical and agricultural antifungals. SDM has been…”
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Identification of Natural RORγ Ligands that Regulate the Development of Lymphoid Cells by Santori, Fabio R., Huang, Pengxiang, van de Pavert, Serge A., Douglass, Eugene F., Leaver, David J., Haubrich, Brad A., Keber, Rok, Lorbek, Gregor, Konijn, Tanja, Rosales, Brittany N., Rozman, Damjana, Horvat, Simon, Rahier, Alain, Mebius, Reina E., Rastinejad, Fraydoon, Nes, W. David, Littman, Dan R.

“…Mice deficient in the nuclear hormone receptor RORγt have defective development of thymocytes, lymphoid organs, Th17 cells, and type 3 innate lymphoid cells…”
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Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA by Belliveau, Nathan M, Huft, Jens, Lin, Paulo JC, Chen, Sam, Leung, Alex KK, Leaver, Timothy J, Wild, Andre W, Lee, Justin B, Taylor, Robert J, Tam, Ying K, Hansen, Carl L, Cullis, Pieter R

“…Lipid nanoparticles (LNP) are the leading systems for in vivo delivery of small interfering RNA (siRNA) for therapeutic applications. Formulation of LNP siRNA…”
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Highly Unsaturated Fatty Acid Synthesis in Atlantic Salmon: Characterization of ELOVL5- and ELOVL2-like Elongases by Morais, Sofia, Monroig, Oscar, Zheng, Xiaozhong, Leaver, Michael J, Tocher, Douglas R

“…Fish species vary in their capacity to biosynthesize the n-3 long-chain polyunsaturated fatty acids (LC-PUFA), eicosapentaenoic (EPA) and docosahexaenoic (DHA)…”
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Druggable Sterol Metabolizing Enzymes in Infectious Diseases: Cell Targets to Therapeutic Leads by Nes, W David, Chaudhuri, Minu, Leaver, David J

“…Sterol biosynthesis via the mevalonate-isoprenoid pathway produces ergosterol (24β-methyl cholesta-5,7-dienol) necessary for growth in a wide-range of…”
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A nematode sterol C4α-methyltransferase catalyzes a new methylation reaction responsible for sterol diversity[S] by Zhou, Wenxu, Fisher, Paxtyn M., Vanderloop, Boden H., Shen, Yun, Shi, Huazhong, Maldonado, Adrian J., Leaver, David J., Nes, W. David

“…Primitive sterol evolution plays an important role in fossil record interpretation and offers potential therapeutic avenues for human disease resulting from…”
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Analysis of the Arabidopsis Mitochondrial Proteome by Millar, A. Harvey, Sweetlove, Lee J., Giegé, Philippe, Leaver, Christopher J.

“…The complete set of nuclear genes that encode proteins targeted to mitochondria in plants is currently undefined and thus the full range of mitochondrial…”
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Critical Role of Arabidopsis Electron-Transfer Flavoprotein:Ubiquinone Oxidoreductase during Dark-Induced Starvation by Ishizaki, Kimitsune, Larson, Tony R, Schauer, Nicolas, Fernie, Alisdair R, Graham, Ian A, Leaver, Christopher J

“…In mammals, electron-transfer flavoprotein:ubiquinone oxidoreductase (ETFQO) and electron-transfer flavoprotein (ETF) are functionally associated, and ETF…”
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Functional genomics reveals increases in cholesterol biosynthetic genes and highly unsaturated fatty acid biosynthesis after dietary substitution of fish oil with vegetable oils in Atlantic salmon (Salmo salar) by Leaver, Michael J, Villeneuve, Laure An, Obach, Alex, Jensen, Linda, Bron, James E, Tocher, Douglas R, Taggart, John B

“…There is an increasing drive to replace fish oil (FO) in finfish aquaculture diets with vegetable oils (VO), driven by the short supply of FO derived from wild…”
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The impact of oxidative stress on Arabidopsis mitochondria by Sweetlove, L.J., Heazlewood, J.L., Herald, V., Holtzapffel, R., Day, D.A., Leaver, C.J., Millar, A.H.

“…Summary Treatment of Arabidopsis cell culture for 16 h with H2O2, menadione or antimycin A induced an oxidative stress decreasing growth rate and increasing…”
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Three Peroxisome Proliferator-Activated Receptor Isotypes from Each of Two Species of Marine Fish by Leaver, Michael J, Boukouvala, Evridiki, Antonopoulou, Efthimia, Diez, Amalia, Favre-Krey, Laurence, Ezaz, M. Tariq, Bautista, José M, Tocher, Douglas R, Krey, Grigorios

“…The cloning and characterization of cDNAs and genes encoding three peroxisome proliferator-activated receptor (PPAR) isotypes from two species of marine fish,…”
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An evolutionary perspective on Elovl5 fatty acid elongase: comparison of Northern pike and duplicated paralogs from Atlantic salmon by Carmona-Antoñanzas, Greta, Tocher, Douglas R, Taggart, John B, Leaver, Michael J

“…The ability to produce physiologically critical LC-PUFA from dietary fatty acids differs greatly among teleost species, and is dependent on the possession and…”
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Mitochondria‐targeted GFP highlights the heterogeneity of mitochondrial shape, size and movement within living plant cells by Logan, David C., Leaver, Christopher J.

“…Little is known concerning the heterogeneity of mitochondrial shape, size, number, cytoplasmic distribution, and motility in planta. Ultrastructural studies…”
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Sphingolipid long chain base phosphates can regulate apoptotic-like programmed cell death in plants by Alden, Keith P., Dhondt-Cordelier, Sandrine, McDonald, Kerrie L., Reape, Theresa J., Ng, Carl K.-Y., McCabe, Paul F., Leaver, Christopher J.

“…► Evidence sphingolipid long chain base phosphates regulate cell death in plants. ► Sphingosine-1-phosphate can attenuate cell death in Arabidopsis thaliana. ►…”
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The PET1-CMS Mitochondrial Mutation in Sunflower Is Associated with Premature Programmed Cell Death and Cytochrome c Release by Balk, J.

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Coordination of Nuclear and Mitochondrial Genome Expression during Mitochondrial Biogenesis in Arabidopsis by Giegé, Philippe, Sweetlove, Lee J, Cognat, Valérie, Leaver, Christopher J

“…Mitochondrial biogenesis and function require the regulated and coordinated expression of nuclear and mitochondrial genomes throughout plant development and in…”
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Translocation of cytochrome c from the mitochondria to the cytosol occurs during heat-induced programmed cell death in cucumber plants by Balk, Janneke, Leaver, Christopher J, McCabe, Paul F

“…In mammals mitochondria play a critical role in the activation of programmed cell death (PCD). One mechanism by which mitochondria can commit a cell to death…”
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Towards a system level understanding of non-model organisms sampled from the environment: a network biology approach by Williams, Tim D, Turan, Nil, Diab, Amer M, Wu, Huifeng, Mackenzie, Carolynn, Bartie, Katie L, Hrydziuszko, Olga, Lyons, Brett P, Stentiford, Grant D, Herbert, John M, Abraham, Joseph K, Katsiadaki, Ioanna, Leaver, Michael J, Taggart, John B, George, Stephen G, Viant, Mark R, Chipman, Kevin J, Falciani, Francesco

“…The acquisition and analysis of datasets including multi-level omics and physiology from non-model species, sampled from field populations, is a formidable…”
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