Search Results - "Leaver, HA"

Therapeutic implications of disorders of cell death signalling: membranes, micro‐environment, and eicosanoid and docosanoid metabolism by Davidson, J, Rotondo, D, Rizzo, MT, Leaver, HA

“…Disruptions of cell death signalling occur in pathological processes, such as cancer and degenerative disease. Increased knowledge of cell death signalling has…”
Get full text

Acute phase responses following minimal access and conventional thoracic surgery by Craig, S.R., Leaver, H.A., Yap, P.L., Pugh, G.C., Walker, W.S.

“…Objectives: Major thoracic surgery is associated with trauma-related immunological changes. These may impair anti-tumour immunity. We hypothesize that the…”
Get full text

Lymphocyte responses following open and minimally invasive thoracic surgery by LEAVER, H. A, CRAIG, S. R, YAP, P. L, WALKER, W. S

“…Background Immunosuppression associated with surgery may predispose to increased tumour growth or recurrence. Lymphocytes are central components of the immune…”
Get full text

Calcium-sensitive mitochondrial membrane potential in human platelets and intrinsic signals of cell death by Leaver, H. A., Schou, A. C., Rizzo, M. T., Prowse, C. V.

“…The mechanisms involved in storage-induced damage in platelets are not well understood, but membrane signalling via Ca2+ ion flux may affect mitochondrial H+…”
Get full text

The development of necrosis and apoptosis in glioma: experimental findings using spheroid culture systems by Bell, H. S., Whittle, I. R., Walker, M., Leaver, H. A., Wharton, S. B.

“…Cell death in gliomas may occur either by apoptosis, or, in the case of high grade tumours, by necrosis, but questions remain as to the pathogenesis and…”
Get full text

Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology by Leaver, H.A., Wharton, S.B., Bell, H.S., Leaver-Yap, I.M.M., Whittle, I.R.

“…Highly unsaturated fatty acids (HUFAs) are naturally occurring anti-tumour agents. HUFAs act as intracellular signalling molecules in cell proliferation and…”
Get full text

Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma by Leaver, H.A., Bell, H.S., Rizzo, M.T., Ironside, J.W., Gregor, A., Wharton, S.B., Whittle, I.R.

“…The highly unsaturated fatty acids (HUFA) of the n-6 and n-3 series are involved in cell signalling in normal and transformed cells and have recently been…”
Get full text

Intracellular oxidation by human glioma cell populations: effect of arachidonic acid by Leaver, H.A., Williams, J.R., Smith, C., Whittle, I.R.

“…Arachidonic acid (AA) and Gamma linolenic acid have been shown to limit glioma cell growth, stimulate apoptosis and lipid peroxidation. However, brain tumours…”
Get full text

Effects of N-6 essential fatty acids on glioma invasion and growth : experimental studies with glioma spheroids in collagen gels by BELL, H. S, WHARTON, S. B, LEAVER, H. A, WHITTLE, I. R

“…Intracranial infusions of gamma-linolenic acid (GLA), an essential fatty acid, have been used as an adjuvant therapy following malignant glioma resection;…”
Get full text

Apoptosis in human primary brain tumours: actions of arachidonic acid by Williams, J.R., Leaver, H.A., Ironside, J.W., Miller, E.P., Whittle, I.R., Gregor, A.

“…It has been postulated that loss of proliferative control in tumour cells is a consequence of depletion of cellular arachidonic acid (AA) and that exogenous AA…”
Get full text

Effect of blood transfusion on survival after esophagogastrectomy for carcinoma by Craig, Stewart R, Adam, Donald J, Yap, Peng Lee, Leaver, H.Anne, Elton, Robert A, Cameron, Evan W.J, Sang, Christopher T.M, Walker, William S

“…Background. There is growing evidence that blood transfusion is associated with clinical factors that can lead to transfusion-induced immunosuppression. This…”
Get full text

Antitumour actions of highly unsaturated fatty acids: cell signalling and apoptosis by Leaver, H.A., Rizzo, M.T., Whittle, I.R.

Get full text

Prions: Properties, Occurrence, Modes of Transmission and Relevance for Blood Transfusion and Blood Derivatives by Yap, P.L., Leaver, H.A., Gillon, J.

Get full text

Dynamics of reactive oxygen intermediate production in human glioma: n-6 essential fatty acid effects by LEAVER, H. A, WILLIAMS, J. R, IRONSIDE, J. W, MILLER, E. P, GREGOR, A, SU, B. H, PRESCOTT, R. J, WHITTLE, I. R

“…Background Reactive oxygen intermediates (ROIs) are important signals controlling cell growth and cell death. Local essential fatty acid (EFA) deficiencies in…”
Get full text

Kinetics of reactive oxygen intermediate formation and apoptosis in human glioma and glioma C6 cell line: effects of radiation and n-6 essential fatty acids by Williams, J R, Leaver, H A, Ironside, J W, Gregor, A, Miller, E, Whittle, I R

Get more information

Apoptosis in human primary brain tumours by A. Leaver, H., Whittle, I. R., Wharton, S. B., Ironside, J. W.

“…Apoptosis, or programmed cell death, has been recognized for nearly three decades as occurring in many organs in response to different pathophysiological…”
Get full text

Apoptosis and the Dynamics of Infection and Disease by Leaver, H.A., Brock, J.H.

“…Progress in defining the pathways of apoptosis has given new insights into cell dynamics in the immune system. The importance of apoptosis in clonal selection…”
Get full text

Arachidonic acid in the reticuloendothelial network by Leaver, H A, Williams, J R, Dawson, I M, Yap, P L

Get more information

Arachidonic Acid Activation of Monocyte and Neutrophil Reactive Oxygen in Lung Cancer Patients Undergoing Pulmonary Resection by Leaver, H.A., Craig, S.R., Yap, P.L., Williams, J.R., Walker, W.S.

“…Reactive oxygen (roi) generation was investigated in phagocyted of 39 patients undergoing pulmonary resection for lung cancer and 39 paired healthy controls…”
Get full text

The influence of dietary essential fatty acids on uterine C20 and C22 fatty acid composition by Howie, A, Leaver, H A, Wilson, N H, Yap, P L, Aitken, I D

“…The effect of dietary fatty acids on uterine fatty acid composition was studied in rats fed control diet or semi-synthetic diet supplemented with 1.5…”
Get more information