Search Results - "Leary, Eileen"

PSG Validation of minute-to-minute scoring for sleep and wake periods in a consumer wearable device by Cheung, Joseph, Leary, Eileen B, Lu, Haoyang, Zeitzer, Jamie M, Mignot, Emmanuel

“…Actigraphs are wrist-worn devices that record tri-axial accelerometry data used clinically and in research studies. The expense of research-grade actigraphs,…”
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Factors associated with fatigue in patients with insomnia by Kim, Seog Ju, Kim, Somin, Jeon, Sehyun, Leary, Eileen B., Barwick, Fiona, Mignot, Emmanuel

“…Although fatigue is common in insomnia, the clinical associates of fatigue in patients with insomnia are largely unknown. We aimed to investigate the clinical…”
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Results of the SHARP Study: A Randomized, Placebo-Controlled, Double-Blind, Repeated-Measures, Crossover, Phase IV Clinical Trial of the Effect of the Wake-Promoting Agent Solriamfetol on Cognitive Function in Obstructive Sleep Apnea With Excessive Daytime Sleepiness and Cognitive Impairment by Van Dongen, Hans P.A., Leary, Eileen B., Drake, Christopher, Bogan, Richard, Jaeger, Judith, Rosenberg, Russell, Streicher, Caroline, Tabuteau, Herriot

“…Obstructive sleep apnea (OSA) causes episodes of fragmented sleep and intermittent hypoxia and leads to excessive daytime sleepiness (EDS). Deficits in…”
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Association of Rapid Eye Movement Sleep With Mortality in Middle-aged and Older Adults by Leary, Eileen B, Watson, Kathleen T, Ancoli-Israel, Sonia, Redline, Susan, Yaffe, Kristine, Ravelo, Laurel A, Peppard, Paul E, Zou, James, Goodman, Steven N, Mignot, Emmanuel, Stone, Katie L

“…Rapid eye movement (REM) sleep has been linked with health outcomes, but little is known about the relationship between REM sleep and mortality. To investigate…”
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Fatigued but not sleepy? An empirical investigation of the differentiation between fatigue and sleepiness in sleep disorder patients in a cross-sectional study by Suh, Sooyeon, Lok, Renske, Weed, Lara, Cho, Ayeong, Mignot, Emmanuel, Leary, Eileen B., Zeitzer, Jamie M.

“…Sleepiness and fatigue are common complaints among individuals with sleep disorders. The two concepts are often used interchangeably, causing difficulty with…”
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Social support and isolation in narcolepsy and idiopathic hypersomnia: An international survey by Flygare, Julie, Oglesby, Lauren, Parthasarathy, Sairam, Thorpy, Michael J., Mignot, Emmanuel, Leary, Eileen B., Morse, Anne Marie

“…To evaluate factors associated with feeling supported in adjusting to life when diagnosed with narcolepsy or idiopathic hypersomnia. An online survey was…”
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Update in Sleep in 2019 by Leary, Eileen B, Zinchuk, Andrey, Stone, Katie L, Mehra, Reena

“…The results in several outstanding studies in the field of sleep medicine are featured. In a large study of nasal microbiome, the researchers have used a…”
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Sleep disorders, depression and anxiety are associated with adverse safety outcomes in healthcare workers: A prospective cohort study by Weaver, Matthew D., Vetter, Céline, Rajaratnam, Shantha M.W., O’Brien, Conor S., Qadri, Salim, Benca, Ruth M., Rogers, Ann E., Leary, Eileen B., Walsh, James K., Czeisler, Charles A., Barger, Laura K.

“…Summary The objective of the study was to determine if sleep disorder, depression or anxiety screening status was associated with safety outcomes in a diverse…”
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Effectiveness and optimization of low-sodium oxybate in participants with narcolepsy switching from a high-sodium oxybate: data from the Substitution of Equal Grams of Uninterrupted Xyrem to Xywav study by Macfadden, Wayne, Leary, Eileen B, Fuller, Douglas S, Kirby, M Todd, Roy, Asim

“…Low-sodium oxybate (LXB; calcium, magnesium, potassium, and sodium oxybates; Xywav) contains the same active moiety as high-sodium oxybates (SXBs; SXB [Xyrem]…”
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Effects of continuous positive airway pressure on neurocognitive function in obstructive sleep apnea patients: The Apnea Positive Pressure Long-term Efficacy Study (APPLES) by Kushida, Clete A, Nichols, Deborah A, Holmes, Tyson H, Quan, Stuart F, Walsh, James K, Gottlieb, Daniel J, Simon, Jr, Richard D, Guilleminault, Christian, White, David P, Goodwin, James L, Schweitzer, Paula K, Leary, Eileen B, Hyde, Pamela R, Hirshkowitz, Max, Green, Sylvan, McEvoy, Linda K, Chan, Cynthia, Gevins, Alan, Kay, Gary G, Bloch, Daniel A, Crabtree, Tami, Dement, William C

“…To determine the neurocognitive effects of continuous positive airway pressure (CPAP) therapy on patients with obstructive sleep apnea (OSA). The Apnea…”
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Effectiveness and tolerability in people with narcolepsy transitioning from sodium oxybate to low-sodium oxybate: Data from the real-world TENOR study by Bae, Charles J., Zee, Phyllis C., Leary, Eileen B., Fuller, Douglas S., Macfadden, Wayne, Candler, Shawn, Steininger, Teresa L., Husain, Aatif M.

“…The Transition Experience of persons with Narcolepsy taking Oxybate in the Real-world (TENOR) study was conducted to provide real-world insight into the…”
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Proteomic biomarkers of sleep apnea by Ambati, Aditya, Ju, Yo-El, Lin, Ling, Olesen, Alexander N, Koch, Henriette, Hedou, Julien Jacques, Leary, Eileen B, Sempere, Vicente Peris, Mignot, Emmanuel, Taheri, Shahrad

“…Abstract Study Objectives Obstructive sleep apnea (OSA) is characterized by recurrent partial to complete upper airway obstructions during sleep, leading to…”
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Periodic limb movements in sleep: Prevalence and associated sleepiness in the Wisconsin Sleep Cohort by Leary, Eileen B., Moore, Hyatt E., Schneider, Logan D., Finn, Laurel A., Peppard, Paul E., Mignot, Emmanuel

“…•Periodic limb movement index (PLMI) ≥15 highly prevalent in adult population.•The likelihood of having a PLMI ≥15 increased significantly with age.•PLMI ≥15…”
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Corrigendum to “Effectiveness and tolerability in people with narcolepsy transitioning from sodium oxybate to low-sodium oxybate: Data from the real-world TENOR study” [Sleep Med. 109 (2023) 65–74 ISSN 1389–9457] by Bae, Charles J., Zee, Phyllis C., Leary, Eileen B., Fuller, Douglas S., Macfadden, Wayne, Candler, Shawn, Steininger, Teresa L., Husain, Aatif M.

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Dosing and transition characteristics in people with narcolepsy transitioning from sodium oxybate to low-sodium oxybate: Data from the real-world TENOR study by Husain, Aatif M., Zee, Phyllis C., Leary, Eileen B., Fuller, Douglas S., Macfadden, Wayne, Candler, Shawn, Whalen, Marisa, Bae, Charles J.

“…The Transition Experience of persons with Narcolepsy taking Oxybate in the Real-world (TENOR) study assessed the real-world experience of people with…”
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Breathing Disturbances Without Hypoxia Are Associated With Objective Sleepiness in Sleep Apnea by Koch, Henriette, Schneider, Logan Douglas, Finn, Laurel A, Leary, Eileen B, Peppard, Paul E, Hagen, Erika, Sorensen, Helge Bjarup Dissing, Jennum, Poul, Mignot, Emmanuel

“…To determine whether defining two subtypes of sleep-disordered breathing (SDB) events-with or without hypoxia-results in measures that are more strongly…”
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Sleep-stage transitions during polysomnographic recordings as diagnostic features of type 1 narcolepsy by Christensen, Julie Anja Engelhard, Carrillo, Oscar, Leary, Eileen B, Peppard, Paul E, Young, Terry, Sorensen, Helge Bjarrup Dissing, Jennum, Poul, Mignot, Emmanuel

“…Highlights • Nocturnal sleep-stage transitions have diagnostic values for type 1 narcolepsy. • Antidepressants and stimulants have a significant effect on the…”
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Estimation of Apnea-Hypopnea Index Using Deep Learning On 3-D Craniofacial Scans by Hanif, Umaer, Leary, Eileen, Schneider, Logan, Paulsen, Rasmus, Morse, Anne Marie, Blackman, Adam, Schweitzer, Paula, Kushida, Clete A., Liu, Stanley, Jennum, Poul, Sorensen, Helge, Mignot, Emmanuel

“…Obstructive sleep apnea (OSA) is characterized by decreased breathing events that occur through the night, with severity reported as the apnea-hypopnea index…”
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Design of a deep learning model for automatic scoring of periodic and non-periodic leg movements during sleep validated against multiple human experts by Carvelli, Lorenzo, Olesen, Alexander N., Brink-Kjær, Andreas, Leary, Eileen B., Peppard, Paul E., Mignot, Emmanuel, Sørensen, Helge B.D., Jennum, Poul

“…Currently, manual scoring is the gold standard of leg movement scoring (LMs) and periodic LMs (PLMS) in overnight polysomnography (PSG) studies, which is…”
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Health-related impact of illness associated with excessive daytime sleepiness in patients with obstructive sleep apnea by Grandner, Michael A., Min, Jae S., Saad, Ragy, Leary, Eileen B., Eldemir, Lev, Hyman, Danielle

“…Approximately 1 billion people worldwide have a sleep disorder called obstructive sleep apnea (OSA). People with OSA experience a blockage in their upper…”
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