Search Results - "Leao, Katarina E."

Decreasing dorsal cochlear nucleus activity ameliorates noise-induced tinnitus perception in mice by Malfatti, Thawann, Ciralli, Barbara, Hilscher, Markus M, Leao, Richardson N, Leao, Katarina E

“…The dorsal cochlear nucleus (DCN) is a region known to integrate somatosensory and auditory inputs and is identified as a potential key structure in the…”
Get full text

Loud noise-exposure changes the firing frequency of subtypes of layer 5 pyramidal neurons and Martinotti cells in the mouse auditory cortex by Nogueira, Ingrid, Lima, Thiago Z, Malfatti, Thawann, Leao, Katarina E

“…Loud noise-exposure can generate noise-induced tinnitus in both humans and animals. Imaging and studies show that noise exposure affects the auditory cortex;…”
Get full text

Chrna2-Martinotti Cells Synchronize Layer 5 Type A Pyramidal Cells via Rebound Excitation by Hilscher, Markus M, Leão, Richardson N, Edwards, Steven J, Leão, Katarina E, Kullander, Klas

“…Martinotti cells are the most prominent distal dendrite-targeting interneurons in the cortex, but their role in controlling pyramidal cell (PC) activity is…”
Get full text

Hyperpolarization-activated currents are differentially expressed in mice brainstem auditory nuclei by Leao, Katarina E., Leao, Richardson N., Sun, Hong, Fyffe, Robert E. W., Walmsley, Bruce

“…The hyperpolarization-activated cation current ( I h ) may influence precise auditory processing by modulating resting membrane potential and cell…”
Get full text

OLM interneurons differentially modulate CA3 and entorhinal inputs to hippocampal CA1 neurons by Leão, Richardson N, Mikulovic, Sanja, Leão, Katarina E, Munguba, Hermany, Gezelius, Henrik, Enjin, Anders, Patra, Kalicharan, Eriksson, Anders, Loew, Leslie M, Tort, Adriano B L, Kullander, Klas

“…The authors selectively target a population of hippocampal interneurons called oriens lacunosum-moleculare (OLM) cells with the Chrna2 promoter to demonstrate…”
Get full text

Unraveling the role of Slc10a4 in auditory processing and sensory motor gating: Implications for neuropsychiatric disorders? by Ciralli, Barbara, Malfatti, Thawann, Hilscher, Markus M., Leao, Richardson N., Cederroth, Christopher R., Leao, Katarina E., Kullander, Klas

“…Psychiatric disorders, such as schizophrenia, are complex and challenging to study, partly due to the lack of suitable animal models. However, the absence of…”
Get full text

Anxiety-like behavior induced by salicylate depends on age and can be prevented by a single dose of 5-MeO-DMT by Winne, Jessica, Boerner, Barbara C., Malfatti, Thawann, Brisa, Elis, Doerl, Jhulimar, Nogueira, Ingrid, Leão, Katarina E., Leão, Richardson N.

“…Salicylate intoxication is a cause of tinnitus and comorbidly associated with anxiety in humans. In a previous work, we showed that salicylate induces…”
Get full text

Alterations of auditory sensory gating in mice with noise-induced tinnitus treated with nicotine and cannabis extract by Ciralli, Barbara, Malfatti, Thawann, Lima, Thiago Z, Silva, Sérgio Ruschi B, Cederroth, Christopher R, Leao, Katarina E

“…Tinnitus is a phantom sound perception affecting both auditory and limbic structures. The mechanisms of tinnitus remain unclear and it is debatable whether…”
Get full text

5-MeO-DMT induces sleep-like LFP spectral signatures in the hippocampus and prefrontal cortex of awake rats by Souza, Annie C., Souza, Bryan C., França, Arthur, Moradi, Marzieh, Souza, Nicholy C., Leão, Katarina E., Tort, Adriano B. L., Leão, Richardson N., Lopes-dos-Santos, Vítor, Ribeiro, Sidarta

“…5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a potent classical psychedelic known to induce changes in locomotion, behaviour, and sleep in rodents. However,…”
Get full text

Serotonergic psychedelic 5-MeO-DMT alters plasticity-related gene expression and generates anxiolytic effects in stressed mice by Nogueira, Margareth, Ferreira Golbert, Daiane C, Menezes, Richardson, Nóbrega de Almeida, Raíssa, Galvão-Coelho, Nicole L, Siroky, Andressa N, Lima, Thiago Z, Maia, Helton, Leão, Katarina E, Leão, Richardson N

“…Serotonergic psychedelics have potential therapeutic effects in treating anxiety and mood disorders, often after a single dose, and are suggested to have…”
Get full text

Chrna2‐OLM interneurons display different membrane properties and h‐current magnitude depending on dorsoventral location by Hilscher, Markus M., Nogueira, Ingrid, Mikulovic, Sanja, Kullander, Klas, Leão, Richardson N., Leão, Katarina E.

“…The hippocampus is an extended structure displaying heterogeneous anatomical cell layers along its dorsoventral axis. It is known that dorsal and ventral…”
Get full text

Firing properties of Renshaw cells defined by Chrna2 are modulated by hyperpolarizing and small conductance ion currents Ih and ISK by Perry, Sharn, Gezelius, Henrik, Larhammar, Martin, Hilscher, Markus M., Lamotte d'Incamps, Boris, Leao, Katarina E., Kullander, Klas

“…Renshaw cells in the spinal cord ventral horn regulate motoneuron output through recurrent inhibition. Renshaw cells can be identified in vitro using…”
Get full text

Author Correction: 5-MeO-DMT induces sleep-like LFP spectral signatures in the hippocampus and prefrontal cortex of awake rats by Souza, Annie C., Souza, Bryan C., França, Arthur, Moradi, Marzieh, Souza, Nicholy C., Leão, Katarina E., Tort, Adriano B. L., Leão, Richardson N., Lopes-dos-Santos, Vítor, Ribeiro, Sidarta

Get full text

Developmental Disruption of Recurrent Inhibitory Feedback Results in Compensatory Adaptation in the Renshaw Cell-Motor Neuron Circuit by Enjin, Anders, Perry, Sharn, Hilscher, Markus M, Nagaraja, Chetan, Larhammar, Martin, Gezelius, Henrik, Eriksson, Anders, Leão, Katarina E, Kullander, Klas

“…When activating muscles, motor neurons in the spinal cord also activate Renshaw cells, which provide recurrent inhibitory feedback to the motor neurons. The…”
Get full text

Salicylate induces anxiety‐like behavior and slow theta oscillation and abolishes the relationship between running speed and fast theta oscillation frequency by Winne, Jessica, Franzon, Rafael, de Miranda, Aron, Malfatti, Thawann, Patriota, João, Mikulovic, Sanja, Leão, Katarina E., Leão, Richardson N.

“…Salicylate intoxication is a cause of tinnitus in humans and it is often used to produce tinnitus‐like perception in animal models. Here, we assess whether…”
Get full text

Sensorimotor function is modulated by the serotonin receptor 1d, a novel marker for gamma motor neurons by Enjin, Anders, Leão, Katarina E., Mikulovic, Sanja, Le Merre, Pierre, Tourtellotte, Warren G., Kullander, Klas

“…Gamma motor neurons (MNs), the efferent component of the fusimotor system, regulate muscle spindle sensitivity. Muscle spindle sensory feedback is required for…”
Get full text

Using Cortical Neuron Markers to Target Cells in the Dorsal Cochlear Nucleus by Malfatti, Thawann, Ciralli, Barbara, Hilscher, Markus M, Edwards, Steven J, Kullander, Klas, Leao, Richardson N, Leao, Katarina E

“…The dorsal cochlear nucleus (DCN) is a region of particular interest for auditory and tinnitus research. However, lack of useful genetic markers for…”
Get full text

Modulation of dendritic synaptic processing in the lateral superior olive by hyperpolarization-activated currents by Leão, Katarina E., Leão, Richardson N., Walmsley, Bruce

“…We have previously shown that mice lateral superior olive (LSO) neurons exhibit a large hyperpolarization‐activated current (Ih), and that…”
Get full text

Altered sodium currents in auditory neurons of congenitally deaf mice by Leão, Richardson N., Naves, Marcell M., Leão, Katarina E., Walmsley, Bruce

“…Sodium currents are essential for action potential generation and propagation in most excitable cells. Appropriate tuning of these currents can be modulated…”
Get full text

Sound stimulation modulates high-threshold K+ currents in mouse auditory brainstem neurons by Leão, Katarina E., Leão, Richardson N., Deardorff, Adam S., Garrett, Andrew, Fyffe, Robert, Walmsley, Bruce

“…The auditory system provides a valuable experimental model to investigate the role of sensory activity in regulating neuronal membrane properties. In this…”
Get full text