Search Results - "Leander Witte"
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Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination
Published in Nature (London) (26-01-2023)“…Feedback inhibition of humoral immunity by antibodies was first documented in 1909 1 . Subsequent studies showed that, depending on the context, antibodies can…”
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Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape
Published in Nature communications (19-01-2023)“…Waves of SARS-CoV-2 infection have resulted from the emergence of viral variants with neutralizing antibody resistance mutations. Simultaneously, repeated…”
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Journal Article -
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Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection in humans
Published in The Journal of experimental medicine (05-12-2022)“…Individuals who receive a third mRNA vaccine dose show enhanced protection against severe COVID-19, but little is known about the impact of breakthrough…”
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Journal Article -
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Zika virus prM protein contains cholesterol binding motifs required for virus entry and assembly
Published in Nature communications (13-11-2023)“…For successful infection of host cells and virion production, enveloped viruses, including Zika virus (ZIKV), extensively rely on cellular lipids. However, how…”
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Journal Article -
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Zika virus prM protein contains cholesterol binding motifs required for virus entry and assembly - Molecular Dynamics Simulation Dataset
Published 13-11-2023“…The molecular dynamics (MD) simulation dataset. The contents: 5ire_BIOMT_expanded.pdb: The complete biological assembly of the cryo-EM structure of Zika Virus…”
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