Search Results - "Leal, Walter S."

Odorant Reception in Insects: Roles of Receptors, Binding Proteins, and Degrading Enzymes by Leal, Walter S

“…Our knowledge of the molecular basis of odorant reception in insects has grown exponentially over the past decade. Odorant receptors (ORs) from moths, fruit…”
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Acute olfactory response of Culex mosquitoes to a human- and bird-derived attractant by Syed, Zainulabeuddin, Leal, Walter S

“…West Nile virus, which is transmitted by Culex mosquitoes while feeding on birds and humans, has emerged as the dominant vector borne disease in North America…”
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Mosquitoes smell and avoid the insect repellent DEET by Syed, Zainulabeuddin, Leal, Walter S

“…The insect repellent DEET is effective against a variety of medically important pests, but its mode of action still draws considerable debate. The widely…”
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The enigmatic reception of DEET—the gold standard of insect repellents by Leal, Walter S

“…•Repellents and substances causing contact disengagement.•DEET as an odorant and a tastant.•Natural is not synonym of safe.•An intact olfactory system is…”
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Mosquito odorant receptor for DEET and methyl jasmonate by Xu, Pingxi, Choo, Young-Moo, De La Rosa, Alyssa, Leal, Walter S.

“…Insect repellents are important prophylactic tools for travelers and populations living in endemic areas of malaria, dengue, encephalitis, and other…”
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Fatty acid solubilizer from the oral disk of the blowfly by Ishida, Yuko, Ishibashi, Jun, Leal, Walter S

“…Blowflies are economic pests of the wool industry and potential vectors for epidemics. The establishment of a pesticide-free, environmentally friendly blowfly…”
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Structure of an Odorant-Binding Protein from the Mosquito Aedes aegypti Suggests a Binding Pocket Covered by a pH-Sensitive “Lid” by Leite, Ney Ribeiro, Krogh, Renata, Xu, Wei, Ishida, Yuko, Iulek, Jorge, Leal, Walter S, Oliva, Glaucius

“…Background: The yellow fever mosquito, Aedes aegypti, is the primary vector for the viruses that cause yellow fever, mostly in tropical regions of Africa and…”
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Snapshot of insect–fungus arms race by Leal, Walter S.

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Genome Analysis and Expression Patterns of Odorant-Binding Proteins from the Southern House Mosquito Culex pipiens quinquefasciatus by Pelletier, Julien, Leal, Walter S

“…Olfactory-based behaviors in mosquitoes are mediated by odorant-binding proteins (OBPs). They form a multigenic family involved in the peripheral events in…”
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Differential expression of olfactory genes in the southern house mosquito and insights into unique odorant receptor gene isoforms by Leal, Walter S., Choo, Young-Moo, Xu, Pingxi, da Silva, Cherre S. B., Ueira-Vieira, Carlos

“…The southern house mosquito, Culex quinquefasciatus, has one of the most acute and eclectic olfactory systems of all mosquito species hitherto studied. Here,…”
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Chiral discrimination of the Japanese beetle sex pheromone and a behavioral antagonist by a pheromone-degrading enzyme by Ishida, Yuko, Leal, Walter S

“…The sophistication of the insect olfactory system is elegantly demonstrated by the reception of sex pheromone by the Japanese beetle. In this insect, two…”
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Crystal and solution structures of an odorant-binding protein from the southern house mosquito complexed with an oviposition pheromone by Mao, Yang, Xu, Xianzhong, Xu, Wei, Ishida, Yuko, Leal, Walter S., Ames, James B., Clardy, Jon, Meinwald, Jerrold

“…Culex mosquitoes introduce the pathogens responsible for filariasis, West Nile virus, St. Louis encephalitis, and other diseases into humans. Currently, traps…”
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Identification and characterization of an antennae-specific aldehyde oxidase from the navel orangeworm by Choo, Young-Moo, Pelletier, Julien, Atungulu, Elizabeth, Leal, Walter S

“…Antennae-specific odorant-degrading enzymes (ODEs) are postulated to inactivate odorant molecules after they convey their signal. Different classes of insect…”
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Pheromone discrimination by a pH-tuned polymorphism of the Bombyx mori pheromone-binding protein by Damberger, Fred F., Michel, Erich, Ishida, Yuko, Leal, Walter S., Wüthrich, Kurt

“…The Bombyx mori pheromone-binding protein (BmorPBP) is known to adopt two different conformations. These are BmorPBP ᴬ, where a regular helix formed by the…”
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Crystallographic observation of pH-induced conformational changes in the Amyelois transitella pheromone-binding protein AtraPBP1 by di Luccio, Eric, Ishida, Yuko, Leal, Walter S, Wilson, David K

“…The navel orangeworm, Amyelois transitella is a major agricultural pest causing large losses in a variety of tree crops. Control of this insect pest may be…”
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Methyl dihydrojasmonate and lilial are the constituents with an "off-label" insect repellence in perfumes by Zeng, Fangfang, Xu, Pingxi, Tan, Kaiming, Zarbin, Paulo H G, Leal, Walter S

“…Insect repellents are widely used to fend off nuisance mosquitoes and, more importantly, to reduce or eliminate mosquito bites in areas where viruses and other…”
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Odorant Receptor from the Southern House Mosquito Culex pipiens quinquefasciatus Sensitive to Oviposition Attractants by Pelletier, Julien, Hughes, David T, Luetje, Charles W, Leal, Walter S

“…Background: Insect odorant receptors (ORs) are heteromers comprised of highly variable odorant-binding subunits associated with one conserved co-receptor. They…”
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Reverse and conventional chemical ecology approaches for the development of oviposition attractants for Culex mosquitoes by Leal, Walter S, Barbosa, Rosângela M R, Xu, Wei, Ishida, Yuko, Syed, Zainulabeuddin, Latte, Nicolas, Chen, Angela M, Morgan, Tania I, Cornel, Anthony J, Furtado, André

“…Synthetic mosquito oviposition attractants are sorely needed for surveillance and control programs for Culex species, which are major vectors of pathogens…”
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DEET as a feeding deterrent by Lu, WeiYu, Hwang, Justin K, Zeng, Fangfang, Leal, Walter S

“…The insect repellent N,N-diethyl-3-methylbenzamide (DEET), is a multimodal compound that acts as a spatial repellent as well as an irritant (contact…”
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A popular Indian clove-based mosquito repellent is less effective against Culex quinquefasciatus and Aedes aegypti than DEET by Tan, Kaiming, Faierstein, Gabriel B, Xu, Pingxi, Barbosa, Rosângela M R, Buss, Garrison K, Leal, Walter S

“…Insect repellents are widely used as the first line of defense against mosquito bites and transmission of disease-causing agents. However, the cost of daily…”
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