Search Results - "Leal, Sandra"
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1
Development of Antibacterial and Antifungal Triazole Chromium(III) and Cobalt(II) Complexes: Synthesis and Biological Activity Evaluations
Published in Molecules (Basel, Switzerland) (13-08-2018)“…In this work, six complexes ( ⁻ ) of Cr(III) and Co(II) transition metals with triazole ligands were synthesized and characterized. In addition, a new ligand,…”
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2
Pharmacologic Therapy for Type 2 Diabetes: Synopsis of the 2017 American Diabetes Association Standards of Medical Care in Diabetes
Published in Annals of internal medicine (18-04-2017)“…The American Diabetes Association (ADA) annually updates the Standards of Medical Care in Diabetes to provide clinicians, patients, researchers, payers, and…”
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3
Treatment of Type 1 Diabetes: Synopsis of the 2017 American Diabetes Association Standards of Medical Care in Diabetes
Published in Annals of internal medicine (03-10-2017)“…The American Diabetes Association (ADA) annually updates Standards of Medical Care in Diabetes to provide clinicians, patients, researchers, payers, and other…”
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4
Chemical composition and antiprotozoal activities of Colombian Lippia spp essential oils and their major components
Published in Memórias do Instituto Oswaldo Cruz (01-03-2010)“…The chemical composition and biological activities of 19 essential oils and seven of their major components were tested against free and intracellular forms of…”
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5
Donor oocyte cycle characteristics and outcomes: factors potentially linked with successful endings
Published in JBRA assisted reproduction (2023)“…The use of donor oocytes in assisted reproduction has seen a significant rise worldwide in the last two decades. Postponement of motherhood and premature…”
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6
Vanadium polypyridyl compounds as potential antiparasitic and antitumoral agents: New achievements
Published in Journal of inorganic biochemistry (01-02-2011)“…In the search for new therapeutic tools against diseases produced by kinetoplastid parasites five vanadyl complexes, [VIVO(L-2H)(phen)], including…”
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Tramadol and Tapentadol Induce Conditioned Place Preference with a Differential Impact on Rewarding Memory and Incubation of Craving
Published in Pharmaceuticals (Basel, Switzerland) (07-01-2023)“…Tramadol and tapentadol, synthetic opioids commonly prescribed for moderate-to-severe pain, have a unique pharmacology that optimizes their analgesia and…”
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8
Unhealthy Diets Induce Distinct and Regional Effects on Intestinal Inflammatory Signalling Pathways and Long-Lasting Metabolic Dysfunction in Rats
Published in International journal of molecular sciences (19-09-2022)“…The intestinal epithelium is a principal site for environmental agents’ detection. Several inflammation- and stress-related signalling pathways have been…”
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Analysis of Progressive Muscle Relaxation on Psychophysiological Variables in Basketball Athletes
Published in International journal of environmental research and public health (19-12-2022)“…The purpose of this study was to evaluate the effects of a progressive muscle relaxation program on psychological (stress levels, anxiety, and mood states) and…”
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10
Gut Microbiome Composition and Metabolic Status Are Differently Affected by Early Exposure to Unhealthy Diets in a Rat Model
Published in Nutrients (17-09-2021)“…Childhood is a critical stage of development during which diet can have profound influence on the microbiota–host interactions, leading to potentially lifelong…”
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11
Unraveling the Hippocampal Molecular and Cellular Alterations behind Tramadol and Tapentadol Neurobehavioral Toxicity
Published in Pharmaceuticals (Basel, Switzerland) (17-06-2024)“…Tramadol and tapentadol are chemically related opioids prescribed for the analgesia of moderate to severe pain. Although safer than classical opioids, they are…”
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12
Nursing care for patient in postoperatory heart surgery in the Intensive Care Unit
Published in Revista Brasileira de Enfermagem (01-01-2021)“…ABSTRACT Objective: To investigate the critical nodes related to nursing care for patients in the postoperative period of cardiac surgery. Methods: Exploratory…”
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13
Identification of a new amide-containing thiazole as a drug candidate for treatment of Chagas' disease
Published in Antimicrobial agents and chemotherapy (01-03-2015)“…Although the parasitic infection Chagas' disease was described over 100 years ago, even now there are not suitable drugs. The available drugs nifurtimox and…”
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14
Exploring tea and herbal infusions consumption patterns and behaviours: The case of Portuguese consumers
Published in Heliyon (15-04-2024)“…Consumption of tea and herbal infusions (THIs) have a long history in traditional medicine and cultural practices. The health-promoting benefits attributed to…”
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15
Optimization of Antitrypanosomatid Agents: Identification of Nonmutagenic Drug Candidates with in Vivo Activity
Published in Journal of medicinal chemistry (22-05-2014)“…Chagas disease, caused by Trypanosoma cruzi parasite, was described thousands of years ago. Currently, it affects millions of people, mostly in Latin America,…”
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Repeated Administration of Clinical Doses of Tramadol and Tapentadol Causes Hepato- and Nephrotoxic Effects in Wistar Rats
Published in Pharmaceuticals (Basel, Switzerland) (10-07-2020)“…Tramadol and tapentadol are fully synthetic and extensively used analgesic opioids, presenting enhanced therapeutic and safety profiles as compared with their…”
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17
Adherence to the Mediterranean diet in young male soccer players
Published in BMC nutrition (04-09-2023)“…Abstract Introduction Nutrition is vital in health and sports performance by improving anthropometric-related parameters and dietary habits, especially in the…”
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Development of bis-thiazoles as inhibitors of triosephosphate isomerase from Trypanosoma cruzi. Identification of new non-mutagenic agents that are active in vivo
Published in European journal of medicinal chemistry (15-07-2015)“…The neglected disease American trypanosomiasis is one of the major health problems in Latin America. Triosephosphate isomerase from Trypanosoma cruzi (TcTIM),…”
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Repeated Administration of Clinically Relevant Doses of the Prescription Opioids Tramadol and Tapentadol Causes Lung, Cardiac, and Brain Toxicity in Wistar Rats
Published in Pharmaceuticals (Basel, Switzerland) (27-01-2021)“…Tramadol and tapentadol, two structurally related synthetic opioid analgesics, are widely prescribed due to the enhanced therapeutic profiles resulting from…”
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20
Inhibition of C. albicans Dimorphic Switch by Cobalt(II) Complexes with Ligands Derived from Pyrazoles and Dinitrobenzoate: Synthesis, Characterization and Biological Activity
Published in International journal of molecular sciences (01-07-2019)“…Seven cobalt(II) complexes of pyrazole derivatives and dinitrobenzoate ligands were synthesized and characterized. The single-crystal X-ray diffraction…”
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