Search Results - "Leal, Julliano Guerin"
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Evaluation of the effect of synthetic compounds derived from azidothymidine on MDA-MB-231 type breast cancer cells
Published in Bioorganic & medicinal chemistry letters (01-09-2020)“…[Display omitted] The present study aimed to investigate the effect of AZT derivates containing tellurium (Te) on human breast cancer cell lines and the…”
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Co-Delivery of an Innovative Organoselenium Compound and Paclitaxel by pH-Responsive PCL Nanoparticles to Synergistically Overcome Multidrug Resistance in Cancer
Published in Pharmaceutics (01-05-2024)“…In this study, we designed the association of the organoselenium compound 5'-Seleno-(phenyl)-3'-(ferulic-amido)-thymidine (AFAT-Se), a promising innovative…”
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In silico evidences of Mpro inhibition by a series of organochalcogen-AZT derivatives and their safety in Caenorhabditis elegans
Published in Journal of trace elements in medicine and biology (01-12-2023)“…The new coronavirus (SARS-CoV-2) pandemic emerged in 2019 causing millions of deaths. Vaccines were quickly developed and made available in 2021. Despite the…”
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