Search Results - "Leal, Jorge Henrique Santos"
-
1
Checkpoint Blockade Strategies in the Treatment of Breast Cancer: Where We Are and Where We Are Heading
Published in Current treatment options in oncology (01-04-2019)“…Opinion Statement Immunotherapy has become one of the greatest advances in medical oncology over the last century; however, the optimal application for the…”
Get full text
Journal Article -
2
Taste disorders following cancer treatment: report of a case series
Published in Supportive care in cancer (01-12-2019)“…Purpose To present the findings of combined oral assessment and gustometry testing of a series of head and neck and hematologic malignancies in patients with…”
Get full text
Journal Article -
3
Breast Cancer Immunotherapy: From Biology to Current Clinical Applications
Published in European Medical Journal (Chelmsford, England) (23-06-2020)“…Therapeutic strategies for the treatment of breast cancer have historically been determined by the presence or absence of hormone receptors and HER2…”
Get full text
Journal Article -
4
Abstract PO3-05-03: Real-World Data on First-line Treatment of Hormone Receptor-positive, HER2-negative, Metastatic Breast Cancer in Brazil (BRAVE study - LACOG 0221)
Published in Cancer research (Chicago, Ill.) (02-05-2024)“…Introduction: Endocrine therapy (ET) plus CDK 4/6 inhibitors is considered the standard of care as first-line therapy in hormone receptor positive (HR+)/HER2…”
Get full text
Journal Article -
5
Abstract PO5-19-07: A Single Arm Phase 2 Study of Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Hormone Receptor-Negative, HER2-Negative Early Stage/Resectable Breast Cancer
Published in Cancer research (Chicago, Ill.) (02-05-2024)“…Background: Triple negative breast cancer (TNBC) is a biologically distinct subtype with a high risk of early relapse. Patients not achieving a pathological…”
Get full text
Journal Article -
6
Abstract PO5-19-08: Neoadjuvant HER2-targeted Therapy +/- Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial
Published in Cancer research (Chicago, Ill.) (02-05-2024)“…Background: Immune checkpoint inhibition (ICI) is synergistic with HER2-directed therapy in pre-clinical models. Clinically, pembrolizumab (K)-mediated ICI…”
Get full text
Journal Article -
7
Abstract OT3-25-01: Neoadjuvant HER2-targeted Therapy +/- Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial
Published in Cancer research (Chicago, Ill.) (01-03-2023)“…Background: Immune checkpoint inhibition (ICI) is synergistic with HER2-directed therapy in pre-clinical models. Clinically, pembrolizumab (K)-mediated ICI…”
Get full text
Journal Article -
8
Abstract OT1-19-01: A Single Arm Phase 2 Study of Peri-Operative Checkpoint-Mediated Immune Therapy and Cryoablation in Women with Hormone Receptor-Negative, HER2-Negative Early Stage/Resectable Breast Cancer
Published in Cancer research (Chicago, Ill.) (01-03-2023)“…Background: Local tumor destruction with cryoablation (cryo) induces inflammation and releases antigens that can activate tumor-specific immune responses…”
Get full text
Journal Article -
9
Abstract OT3-07-01: Real-World Data on First-line Treatment of HR-positive, HER2-negative, Metastatic Breast Cancer in Brazil (BRAVE Study/LACOG 0221)
Published in Cancer research (Chicago, Ill.) (01-03-2023)“…Background: It is estimated that 50 thousand patients live with metastatic breast cancer (MBC) in Brazil. A recent Brazilian registry (LACOG 0312) on MBC…”
Get full text
Journal Article