Search Results - "Leal, Grace"
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Variation in Aedes aegypti Mosquito Competence for Zika Virus Transmission
Published in Emerging infectious diseases (01-04-2017)“…To test whether Zika virus has adapted for more efficient transmission by Aedes aegypti mosquitoes, leading to recent urban outbreaks, we fed mosquitoes from…”
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Chikungunya virus emergence is constrained in Asia by lineage-specific adaptive landscapes
Published in Proceedings of the National Academy of Sciences - PNAS (10-05-2011)“…Adaptation of RNA viruses to a new host or vector species often results in emergence of new viral lineages. However, lineage-specific restrictions on the…”
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3
Attenuation of Chikungunya Virus Vaccine Strain 181/Clone 25 Is Determined by Two Amino Acid Substitutions in the E2 Envelope Glycoprotein
Published in Journal of Virology (01-06-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Zika Virus Vector Competency of Mosquitoes, Gulf Coast, United States
Published in Emerging infectious diseases (01-03-2017)“…Zika virus has recently spread throughout the Americas. Although Aedes aegypti mosquitoes are considered the primary vector, Culex quinquefasciatus and…”
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5
A Rodent Model of Chikungunya Virus Infection in RAG1 -/- Mice, with Features of Persistence, for Vaccine Safety Evaluation
Published in PLoS neglected tropical diseases (26-06-2015)“…Chikungunya virus (CHIKV) is a positive sense, single stranded RNA virus in the genus Alphavirus, and the etiologic agent of epidemics of severe arthralgia in…”
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6
IRES-Containing VEEV Vaccine Protects Cynomolgus Macaques from IE Venezuelan Equine Encephalitis Virus Aerosol Challenge
Published in PLoS neglected tropical diseases (01-05-2015)“…Venezuelan equine encephalitis virus (VEEV) is an arbovirus endemic to the Americas that is responsible for severe, sometimes fatal, disease in humans and…”
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Genetic and anatomic determinants of enzootic Venezuelan equine encephalitis virus infection of Culex (Melanoconion) taeniopus
Published in PLoS neglected tropical diseases (01-04-2012)“…Venezuelan equine encephalitis (VEE) is a re-emerging, mosquito-borne viral disease with the potential to cause fatal encephalitis in both humans and equids…”
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8
Multi-peaked adaptive landscape for chikungunya virus evolution predicts continued fitness optimization in Aedes albopictus mosquitoes
Published in Nature communications (16-06-2014)“…Host species-specific fitness landscapes largely determine the outcome of host switching during pathogen emergence. Using chikungunya virus (CHIKV) to study…”
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9
Outbreak of Zika Virus Infection, Chiapas State, Mexico, 2015, and First Confirmed Transmission by Aedes aegypti Mosquitoes in the Americas
Published in The Journal of infectious diseases (01-11-2016)“…Background. After decades of obscurity, Zika virus (ZIKV) has spread through the Americas since 2015 accompanied by congenital microcephaly and Guillain-Barré…”
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10
A chikungunya fever vaccine utilizing an insect-specific virus platform
Published in Nature medicine (01-02-2017)“…New vaccine approaches that safely elicit immunity are needed to protect against infectious disease. Erasmus et al . report their development of an…”
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11
Differential Vector Competency of Aedes albopictus Populations from the Americas for Zika Virus
Published in The American journal of tropical medicine and hygiene (01-08-2017)“…To evaluate the potential role of s (Skuse) as a vector of Zika virus (ZIKV), colonized mosquitoes of low generation number (≤ F5) from Brazil, Houston, and…”
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12
Novel Insect-Specific Eilat Virus-Based Chimeric Vaccine Candidates Provide Durable, Mono- and Multivalent, Single-Dose Protection against Lethal Alphavirus Challenge
Published in Journal of virology (15-02-2018)“…Most alphaviruses are mosquito borne and exhibit a broad host range, infecting many different vertebrates, including birds, rodents, equids, humans, and…”
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13
CICLOS DE ESTABILIDAD, CAMBIOS Y VARIABLES LENTAS-RÁPIDAS EN EL PAISAJE DEL ÁREA METROPOLITANA DE CONCEPCIÓN A PARTIR DE ESTUDIOS DE SISTEMAS SOCIO ECOLOGICOS: UN ANÁLISIS EXPLORATORIO
Published in Urbano (Concepción) (01-11-2022)“…RESUMEN Los paisajes son capaces de maximizar sus fortalezas en momentos de estabilidad al desarrollar de manera profunda su carácter y, así, manejar las…”
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14
A vaccine candidate for eastern equine encephalitis virus based on IRES-mediated attenuation
Published in Vaccine (08-02-2012)“…Highlights ► Design of a recombinant EEE virus (EEEV/IRES), as a candidate vaccine for EEEV. ► Subgenomic promoter of wild type EEEV inactivated by IRES-based…”
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15
Recombinant Isfahan Virus and Vesicular Stomatitis Virus Vaccine Vectors Provide Durable, Multivalent, Single-Dose Protection against Lethal Alphavirus Challenge
Published in Journal of virology (15-04-2017)“…The demonstrated clinical efficacy of a recombinant vesicular stomatitis virus (rVSV) vaccine vector has stimulated the investigation of additional…”
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16
Evolution and spread of Venezuelan equine encephalitis complex alphavirus in the Americas
Published in PLoS neglected tropical diseases (01-08-2017)“…Venezuelan equine encephalitis (VEE) complex alphaviruses are important re-emerging arboviruses that cause life-threatening disease in equids during epizootics…”
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A Rodent Model of Chikungunya Virus Infection in RAG1 -/- Mice, with Features of Persistence, for Vaccine Safety Evaluation: e0003800
Published in PLoS neglected tropical diseases (01-06-2015)“…Chikungunya virus (CHIKV) is a positive sense, single stranded RNA virus in the genus Alphavirus, and the etiologic agent of epidemics of severe arthralgia in…”
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18
A chimeric Sindbis-based vaccine protects cynomolgus macaques against a lethal aerosol challenge of eastern equine encephalitis virus
Published in Vaccine (01-03-2013)“…Highlights ► Chimeric vaccines were constructed from a cDNA clone containing genes from divergent EEE strains. ► The immunogenicity of each of the vaccines…”
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IRES-Containing VEEV Vaccine Protects Cynomolgus Macaques from IE Venezuelan Equine Encephalitis Virus Aerosol Challenge: e0003797
Published in PLoS neglected tropical diseases (01-05-2015)“…Venezuelan equine encephalitis virus (VEEV) is an arbovirus endemic to the Americas that is responsible for severe, sometimes fatal, disease in humans and…”
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Journal Article -
20
Genetic and Anatomic Determinants of Enzootic Venezuelan Equine Encephalitis Virus enfection of Culex (Melanoconion) taeniopus
Published in PLoS neglected tropical diseases (01-04-2012)“…Venezuelan equine encephalitis (VEE) is a re-emerging, mosquito-borne viral disease with the potential to cause fatal encephalitis in both humans and equids…”
Get full text
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