Search Results - "Leahy, Sophie"

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  1. 1

    Associations between circadian alignment and cognitive functioning in a nationally representative sample of older adults by Leahy, Sophie, Xiao, Qian, Yeung, Chris Ho Ching, Figueiro, Mariana G.

    Published in Scientific reports (12-06-2024)
    “…Proper alignment of activity-rest and light–dark patterns allows for healthy bodily functions to occur at optimal times of the day. Disruptions to this…”
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    Journal Article
  2. 2

    Tailored lighting intervention (TLI) for improving sleep-wake cycles in older adults living with dementia by Figueiro, Mariana G, Pedler, David, Plitnick, Barbara, Zecena, Erick, Leahy, Sophie

    Published in Frontiers in physiology (18-12-2023)
    “…Sleep disturbance is a hallmark of Alzheimer's disease and related dementias, and caregiver stress caused by patients' nighttime wandering, injuries, and…”
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    Journal Article
  3. 3

    Inner retinal oxygen delivery and metabolism in progressive stages of diabetic retinopathy by Rahimi, Mansour, Hossain, Farzana, Leahy, Sophie, Blair, Norman P., Jiang, Xuejuan, Shahidi, Mahnaz

    Published in Scientific reports (22-02-2024)
    “…Previous studies have reported increased retinal venous oxygen saturation and decreased retinal blood flow and oxygen metabolism in non-proliferative diabetic…”
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    Journal Article
  4. 4

    Retinal Oxygen Delivery, Metabolism, and Extraction Fraction during Long-Term Bilateral Common Carotid Artery Occlusion in Rats by Leahy, Sophie, Farzad, Shayan, Blair, Norman P., Shahidi, Mahnaz

    Published in Scientific reports (25-06-2020)
    “…Retinal functional, biochemical, and anatomical changes have been previously reported in long-term experimental permanent bilateral common carotid artery…”
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    Journal Article
  5. 5

    Retinal Vascular Physiology Biomarkers in a 5XFAD Mouse Model of Alzheimer's Disease by Matei, Nathanael, Leahy, Sophie, Blair, Norman P, Burford, James, Rahimi, Mansour, Shahidi, Mahnaz

    Published in Cells (Basel, Switzerland) (04-08-2022)
    “…Alzheimer's disease (AD) is a neurodegenerative disorder that affects the brain and retina and lacks reliable biomarkers for early diagnosis. As amyloid beta…”
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    Journal Article
  6. 6

    Retinal Oxygen Delivery and Metabolism Response to Hyperoxia During Bilateral Common Carotid Artery Occlusion in Rats by Leahy, Sophie, Matei, Nathanael, Blair, Norman P., Shahidi, Mahnaz

    “…PurposeThe purpose of the current study was to test the hypothesis that responses of total retinal blood flow (TRBF), inner retinal oxygen delivery (DO2),…”
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  7. 7

    Impairments of retinal hemodynamics and oxygen metrics in ocular hypertension-induced ischemia-reperfusion by Rahimi, Mansour, Leahy, Sophie, Matei, Nathanael, Burford, James, Blair, Norman P., Shahidi, Mahnaz

    Published in Experimental eye research (01-12-2022)
    “…Ischemia-reperfusion (I/R) is an established model for retinal neurodegeneration. However, there is limited knowledge of retinal physiological metrics and…”
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    Journal Article
  8. 8

    Assessment of retinal oxygen metabolism, visual function, thickness and degeneration markers after variable ischemia/reperfusion in rats by Matei, Nathanael, Leahy, Sophie, Blair, Norman P., Shahidi, Mahnaz

    Published in Experimental eye research (01-12-2021)
    “…After total retinal ischemia induced experimentally by ophthalmic vessel occlusion followed by reperfusion, studies have reported alterations in retinal oxygen…”
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    Journal Article
  9. 9

    The accumulated oxygen deficit as an indicator of the ischemic retinal insult by Blair, Norman P., Matei, Nathanael, Leahy, Sophie, Rahimi, Mansour, Shahidi, Mahnaz

    Published in Experimental eye research (01-05-2023)
    “…We here attempt to improve quantification of the ischemic retinal insult, that is, what is imposed on the retinal tissue by ischemia, especially in…”
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    Journal Article
  10. 10

    Alterations in retinal pulse wave velocity under experimental ocular hypertension by Shahidi, Mahnaz, Nankali, Amir, Felder, Anthony E., Rahimi, Mansour, Leahy, Sophie, Matei, Nathanael

    Published in Microvascular research (01-07-2023)
    “…Impairments of blood flow and autoregulation have been implicated in diabetic retinopathy and glaucoma. Thus, identifying biomarkers of retinal vascular…”
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    Journal Article
  11. 11

    Control of retinal blood flow levels by selected combinations of cervical arterial ligations in rat by Blair, Norman P., Leahy, Sophie, Nathanael Matei, Shahidi, Mahnaz

    Published in Experimental eye research (01-08-2020)
    “…The effect of various combinations of cervical arterial ligations (Combinations) on retinal blood flow (RBF) levels is not known in rats. We hypothesized: 1)…”
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    Journal Article
  12. 12

    Assessment of inner retinal oxygen metrics and thickness in a mouse model of inherited retinal degeneration by Rahimi, Mansour, Leahy, Sophie, Matei, Nathanael, Blair, Norman P., Jeong, Shinwu, Craft, Cheryl Mae, Shahidi, Mahnaz

    Published in Experimental eye research (01-04-2021)
    “…The retinal degeneration 1 (rd1) mouse is a well-established model of inherited retinal degeneration, displaying photoreceptor degeneration and retinal…”
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    Journal Article
  13. 13

    Relation of Retinal Oxygen Measures to Electrophysiology and Survival Indicators after Permanent, Incomplete Ischemia in Rats by Matei, Nathanael, Leahy, Sophie, Auvazian, Selin, Thomas, Biju, Blair, Norman P., Shahidi, Mahnaz

    Published in Translational stroke research (01-12-2020)
    “…Studies in experimental ischemia models by permanent bilateral common carotid artery occlusion (BCCAO) have reported reduced retinal electrophysiological…”
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    Journal Article
  14. 14

    Variability of Retinal Oxygen Metrics in Healthy and Diabetic Subjects by Rahimi, Mansour, Leahy, Sophie, Blair, Norman P., Shahidi, Mahnaz

    Published in Translational vision science & technology (18-10-2021)
    “…PurposePrevious studies have reported alterations in total retinal blood flow (TRBF), oxygen delivery (DO2), oxygen metabolism (MO2), and oxygen extraction…”
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  15. 15

    Relating Retinal Vascular Oxygen Saturation and Microvasculature Morphology at Progressive Stages of Diabetic Retinopathy by Auvazian, Selin L., Cano, Jennifer, Leahy, Sophie, Karamian, Preny, Kashani, Amir, Moshfeghi, Andrew, Ameri, Hossein, Blair, Norman P., Shahidi, Mahnaz

    Published in Translational vision science & technology (04-05-2021)
    “…PurposeDiabetic retinopathy (DR) is a common cause of vision loss in working age adults and presents changes in retinal vessel oxygenation and morphology. The…”
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    Journal Article