Search Results - "Leahy, Shannon N"
-
1
FMRP activity and control of Csw/SHP2 translation regulate MAPK-dependent synaptic transmission
Published in PLoS biology (26-01-2023)“…Noonan syndrome (NS) and NS with multiple lentigines (NSML) cognitive dysfunction are linked to SH2 domain-containing protein tyrosine phosphatase-2 (SHP2)…”
Get full text
Journal Article -
2
Yeast synaptobrevin, Snc1, engages distinct routes of postendocytic recycling mediated by a sorting nexin, Rcy1-COPI, and retromer
Published in Molecular biology of the cell (15-04-2020)“…The budding yeast v-SNARE, Snc1, mediates fusion of exocytic vesicles to the plasma membrane (PM) and is subsequently recycled back to the Golgi. Postendocytic…”
Get full text
Journal Article -
3
PTPN11/Corkscrew activates local presynaptic MAPK signaling to regulate Synapsin, synaptic vesicle pools, and neurotransmission strength, with a dual requirement in neurons and glia
Published in The Journal of neuroscience (24-04-2024)“…Cytoplasmic protein tyrosine phosphatase (PTP) non-receptor type 11 (PTPN11) and homolog Corkscrew (Csw) regulate the mitogen-activated protein kinase (MAPK)…”
Get full text
Journal Article -
4
RNA-binding FMRP and Staufen sequentially regulate the Coracle scaffold to control synaptic glutamate receptor and bouton development
Published in Development (Cambridge) (01-05-2022)“…Both mRNA-binding Fragile X mental retardation protein (FMRP; Fmr1) and mRNA-binding Staufen regulate synaptic bouton formation and glutamate receptor (GluR)…”
Get full text
Journal Article -
5
Carrier of Wingless (Cow) Regulation of Drosophila Neuromuscular Junction Development
Published in eNeuro (01-03-2020)“…The first Wnt signaling ligand discovered, Wingless [Wg (Wnt1 in mammals)], plays critical roles in neuromuscular junction (NMJ) development, regulating…”
Get full text
Journal Article -
6
FMRP activity and control of Csw/SHP2 translation regulate MAPK-dependent synaptic transmission
Published in PLoS biology (01-01-2023)“…Noonan syndrome (NS) and NS with multiple lentigines (NSML) cognitive dysfunction are linked to SH2 domain-containing protein tyrosine phosphatase-2 (SHP2)…”
Get full text
Journal Article