Search Results - "Leahy, Alice"
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COVID-19 symptom surveillance in immunocompromised children and young people in the UK: a prospective observational cohort study
Published in BMJ open (17-03-2021)“…ObjectivesTo describe the frequency of symptoms compatible with SARS-CoV-2 infection in immunocompromised children and young people in the UK during the…”
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P42 Delayed diagnosis in paediatric sarcoidosis: lessons we can learn
Published in Rheumatology (Oxford, England) (01-10-2019)“…Abstract Background Sarcoidosis is a rare autoinflammatory systemic granulomatous disease that can affect any organ in the body. Paediatric literature does not…”
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OA04 Paediatric APS - children are not just small adults
Published in Rheumatology advances in practice (28-09-2022)“…Abstract Introduction/Background Antiphospholipid syndrome (APS) is a rare autoimmune multisystem disease characterised by thrombosis and pregnancy morbidity…”
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A national consensus management pathway for paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS): results of a national Delphi process
Published in The lancet child & adolescent health (01-02-2021)“…Paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS) is a novel condition that was first reported in April, 2020. We…”
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14. National Training Day Initiative for Rheumatology Grid Trainees
Published in Rheumatology (Oxford, England) (01-12-2017)Get full text
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Attainment of low disease activity and remission targets reduces the risk of severe flare and new damage in childhood lupus
Published in Rheumatology (Oxford, England) (03-08-2022)“…To assess the achievability and effect of attaining low disease activity (LDA) or remission in childhood-onset SLE (cSLE). Attainment of three adult-SLE…”
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P39 Virtual reality headset as an alternative to Entonox for intraarticular corticosteroid injection
Published in Rheumatology advances in practice (28-09-2022)“…Abstract Introduction/Background Intraarticular corticosteroid injection is an important therapeutic approach in paediatric rheumatology that results in…”
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P37 Hypermobile ehlers-danlos syndrome explosion in the UK
Published in Archives of disease in childhood (01-06-2019)“…BackgroundEhlers-Danlos Syndrome (EDS) is a heterogeneous group of collagen disorders. There is controversy regarding clinical diagnosis of hypermobility EDS…”
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Contributors to Organ Damage in Childhood Lupus: Corticosteroid Use and Disease Activity
Published in Rheumatology (Oxford, England) (22-10-2024)“…Awareness of paediatric-specific predictors of damage in Childhood-lupus is needed to inform mitigation measures. To ascertain how clinical and demographic…”
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Panel sequencing links rare, likely damaging gene variants with distinct clinical phenotypes and outcomes in juvenile-onset SLE
Published in Rheumatology (Oxford, England) (23-02-2023)“…Juvenile-onset systemic lupus erythematosus (jSLE) affects 15-20% of lupus patients. Clinical heterogeneity between racial groups, age groups and individual…”
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Limited sensitivity and specificity of the ACR/EULAR-2019 classification criteria for SLE in JSLE?-observations from the UK JSLE Cohort Study
Published in Rheumatology (Oxford, England) (03-11-2021)“…This study aimed to test the performance of the new ACR and EULAR criteria, that include ANA positivity as entry criterion, in JSLE. Performance of the…”
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Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: Data from the UK Juvenile-onset systemic lupus erythematosus cohort study
Published in Lupus (01-10-2021)“…Introduction Juvenile-onset systemic lupus erythematosus (JSLE) is a rare autoimmune/inflammatory disease with significant morbidity and mortality…”
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Real world treatment of juvenile-onset systemic lupus erythematosus: Data from the UK JSLE cohort study
Published in Clinical immunology (Orlando, Fla.) (01-06-2022)“…In the absence of clinical trials evidence, Juvenile-onset Systemic Lupus Erythematosus (JSLE) treatment plans vary. To explore ‘real world’ treatment…”
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Clinical and laboratory phenotypes in juvenile-onset Systemic Lupus Erythematosus across ethnicities in the UK
Published in Lupus (01-04-2021)“…Systemic lupus erythematosus (SLE) is a systemic autoimmune/inflammatory disease. Patients diagnosed with juvenile-onset SLE (jSLE), when compared to…”
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The immune landscape of the inflamed joint defined by spectral flow cytometry
Published in Clinical and experimental immunology (05-08-2024)“…Cellular phenotype and function are altered in different microenvironments. For targeted therapies it is important to understand site-specific cellular…”
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G21 Overlapping clinical profiles when juvenile dermatomyositis presents with coeliac disease
Published in Frontline gastroenterology (01-04-2022)“…Introduction/BackgroundCo-existing immune-mediated conditions including juvenile dermatomyositis (JDM) are well described in coeliac disease. Both conditions…”
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EP37 A need to train paediatric rheumatologists in musculoskeletal ultrasound scanning. How do we move forward?
Published in Rheumatology advances in practice (03-11-2020)“…Abstract Case report – Introduction Musculoskeletal ultrasound is used by clinicians around the world and learning this skill is included in paediatric…”
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Discontinuing adalimumab in patients with controlled juvenile idiopathic arthritis-associated uveitis (ADJUST-Adalimumab in Juvenile Idiopathic Arthritis-associated Uveitis Stopping Trial): study protocol for a randomised controlled trial
Published in Current controlled trials in cardiovascular medicine (27-10-2020)“…Juvenile idiopathic arthritis (JIA)-associated uveitis is a chronic paediatric ocular inflammatory condition that can result in visual impairment. Adalimumab,…”
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Procedures for the content, conduct and format of EULAR/PReS paediatric musculoskeletal ultrasound courses
Published in Rheumatic & musculoskeletal diseases open (01-07-2022)“…BackgroundDespite the worldwide increasing request of education on paediatric musculoskeletal ultrasound (PedMSUS), content, conduct and format of PedMSUS…”
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