Search Results - "Leach, Justin"

Incorporating spatial structure into inclusion probabilities for Bayesian variable selection in generalized linear models with the spike-and-slab elastic net by Leach, Justin M., Aban, Inmaculada, Yi, Nengjun

“…Spike-and-slab priors model predictors as arising from a mixture of distributions: those that should (slab) or should not (spike) remain in the model. The…”
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The spike-and-slab elastic net as a classification tool in Alzheimer's disease by Leach, Justin M, Edwards, Lloyd J, Kana, Rajesh, Visscher, Kristina, Yi, Nengjun, Aban, Inmaculada

“…Alzheimer's disease (AD) is the leading cause of dementia and has received considerable research attention, including using neuroimaging biomarkers to classify…”
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One‐year follow‐up of disease burden and medication changes in patients with myasthenia gravis: From the MG Patient Registry by Lee, Ikjae, Leach, Justin M., Aban, Inmaculada, McPherson, Tarrant, Duda, Petra W., Cutter, Gary

“…Introduction/Aims We studied the progression of myasthenia gravis (MG) disease burden and medication adjustment among MG Patient Registry participants. Methods…”
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The spike-and-slab lasso and scalable algorithm to accommodate multinomial outcomes in variable selection problems by Leach, Justin M., Yi, Nengjun, Aban, Inmaculada, The Alzheimer's Disease Neuroimaging Initiative

“…Spike-and-slab prior distributions are used to impose variable selection in Bayesian regression-style problems with many possible predictors. These priors are…”
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All-Cause Mortality in Reproductive-Aged Females by State: An Analysis of the Effects of Abortion Legislation by Harper, Lorie M., Leach, Justin M., Robbins, Lindsay, Blanchard, Christina, Metz, Torri D., Mazzoni, Sara, Nash, Elizabeth, Szychowski, Jeff

“…To estimate the association between state-level abortion legislation and all-cause mortality among all females of reproductive age and maternal, fetal, and…”
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The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface by Loerch, Sarah, Leach, Justin R., Horner, Steven W., Maji, Debanjana, Jenkins, Jermaine L., Pulvino, Mary J., Kielkopf, Clara L.

“…The transcription elongation and pre-mRNA splicing factor Tat-SF1 associates with the U2 small nuclear ribonucleoprotein (snRNP) of the spliceosome. However,…”
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Bayesian compositional models for ordinal response by Zhang, Li, Zhang, Xinyan, Leach, Justin M, Rahman, AKM F, Yi, Nengjun

“…Ordinal response is commonly found in medicine, biology, and other fields. In many situations, the predictors for this ordinal response are compositional,…”
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Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction by Talkish, Jason, Igel, Haller, Hunter, Oarteze, Horner, Steven W, Jeffery, Nazish N, Leach, Justin R, Jenkins, Jermaine L, Kielkopf, Clara L, Ares, Manuel

“…Stable recognition of the intron branchpoint (BP) by the U2 snRNP to form the pre-spliceosome is the first ATP-dependent step of splicing. Genetic and…”
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Preparation of noninfectious scRNAseq samples from SARS-CoV-2-infected epithelial cells by Osborn, Raven M, Leach, Justin, Zanche, Michelle, Ashton, John M, Chu, ChinYi, Thakar, Juilee, Dewhurst, Stephen, Rosenberger, Sonia, Pavelka, Martin, Pryhuber, Gloria S, Mariani, Thomas J, Anderson, Christopher S

“…Coronavirus disease (COVID-19) is an infectious disease caused by the SARS coronavirus 2 (SARS-CoV-2) virus. Direct assessment, detection, and quantitative…”
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Measuring cognitive function by the SDMT across functional domains: Useful but not sufficient by Leach, Justin M, Cutter, Gary, Golan, Daniel, Doniger, Glen, Zarif, Myassar, Bumstead, Barbara, Buhse, Marijean, Kaczmarek, Olivia, Sethi, Avtej, Covey, Thomas, Penner, Iris-Katharina, Wilken, Jeffrey, Gudesblatt, Mark

“…•SDMT is screening tool often inappropriately treated as a comprehensive measure of cognition.•SDMT was insufficient to distinguish impairment/non-impairment…”
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Nasospheroids permit measurements of CFTR-dependent fluid transport by Guimbellot, Jennifer S, Leach, Justin M, Chaudhry, Imron G, Quinney, Nancy L, Boyles, Susan E, Chua, Michael, Aban, Inmaculada, Jaspers, Ilona, Gentzsch, Martina

“…Expansion of novel therapeutics to all patients with cystic fibrosis (CF) requires personalized CFTR modulator therapy. We have developed nasospheroids, a…”
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Breastfeeding initiation and duration among people with mild chronic hypertension: a secondary analysis of the Chronic Hypertension and Pregnancy trial by Goulding, Alison N., Antoniewicz, Leah, Leach, Justin M., Boggess, Kim, Dugoff, Lorraine, Sibai, Baha, Lawrence, Kirsten, Hughes, Brenna L., Bell, Joseph, Edwards, Rodney K., Gibson, Kelly, Haas, David M., Plante, Lauren, Metz, Torri D., Casey, Brian, Esplin, Sean, Longo, Sherri, Hoffman, Matthew, Saade, George R., Hoppe, Kara K., Foroutan, Janelle, Tuuli, Methodius, Owens, Michelle Y., Simhan, Hyagriv N., Frey, Heather, Rosen, Todd, Palatnik, Anna, Baker, Susan, Reddy, Uma M., Kinzler, Wendy, Su, Emily, Krishna, Iris, Nguyen, Nicki, Norton, Mary E., Skupski, Daniel, El-Sayed, Yasser Y., Ogunyemi, Dotun, Harper, Lorie M., Ambalavanan, Namasivayam, Oparil, Suzanne, Szychowski, Jeff M., Tita, Alan T.

“…Increased duration of breastfeeding improves maternal cardiovascular health and may be especially beneficial in high-risk populations, such as those with…”
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Sickle cell trait and risk of cognitive impairment in African-Americans: The REGARDS cohort by Cahill, Christina R, Leach, Justin M, McClure, Leslie A, Irvin, Marguerite Ryan, Zakai, Neil A, Naik, Rakhi, Unverzagt, Frederick, Wadley, Virginia G, Hyacinth, Hyacinth I, Manly, Jennifer, Judd, Suzanne E, Winkler, Cheryl, Cushman, Mary

“…Sickle cell anemia may be associated with cognitive dysfunction, and some complications of sickle cell anemia might affect those with sickle cell trait (SCT),…”
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All-Cause Mortality in Reproductive-Aged Females by State: An Analysis of the Effects of Abortion Legislation by Harper, Lorie M., Leach, Justin M., Robbins, Lindsay, Blanchard, Christina, Metz, Torri D., Mazzoni, Sara, Nash, Elizabeth, Szychowski, Jeff

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War and Statehood in South Sudan by Manfred Öhm Baden-Baden: Nomos Verlagsgesellschaft, 2014. Pp. 235. £61·30 (hbk) by Leach, Justin D.

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All-Cause Mortality in Reproductive-Aged Females by State: An Analysis of the Effects of Abortion Legislation by Harper, Lorie M., Leach, Justin M., Robbins, Lindsay, Blanchard, Christina, Metz, Torri D., Mazzoni, Sara, Nash, Elizabeth, Szychowski, Jeff

“…ABSTRACT It is estimated that the Supreme Court decision in Dobbs v Jackson Women's Health Organization will leave approximately 33 million US women in states…”
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HIV-1 Rev regulates host transcription and RNA processing factor Tat-SF1 to promote HIV-1 infectivity by Gilardi, Justin, Leach, Justin, Leach, Sarah, Hurlbut, Jordan, Horner, Steven, Chamberlain, Jeffrey, Jenkins, Jermaine, Pulvino, Mary, Dewhurst, Stephen, Kielkopf, Clara

“…Abstract only…”
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Migraine inhibitor olcegepant reduces weight loss and IL-6 release in SARS-CoV-2-infected older mice with neurological signs by Rahman, Shafaqat M, Buchholz, David W, Imbiakha, Brian, Jager, Mason C, Leach, Justin, Osborn, Raven M, Birmingham, Ann O, Dewhurst, Stephen, Aguilar, Hector C, Luebke, Anne E

“…COVID-19 can cause neurological symptoms such as fever, dizziness, and nausea. However, such neurological symptoms of SARS-CoV-2 infection have been hardly…”
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Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia by Berndt, Sonja I., Skibola, Christine F., Vijai, Joseph, Wang, Zhaoming, Kelly, Rachel S., Smedby, Karin E., Cozen, Wendy, Wang, Sophia S., Lan, Qing, Teras, Lauren R., Machado, Moara, Yeager, Meredith, Brooks-Wilson, Angela R., Hartge, Patricia, Purdue, Mark P., Birmann, Brenda M., Vajdic, Claire M., Cocco, Pierluigi, Zhang, Yawei, Giles, Graham G., Zeleniuch-Jacquotte, Anne, Lawrence, Charles, Montalvan, Rebecca, Hutchinson, Amy, Ye, Yuanqing, Call, Timothy G., Shanafelt, Tait D., Novak, Anne J., Kay, Neil E., Liebow, Mark, Cunningham, Julie M., Allmer, Cristine, Hjalgrim, Henrik, Adami, Hans-Olov, Melbye, Mads, Glimelius, Bengt, Chang, Ellen T., Glenn, Martha, Curtin, Karen, Cannon-Albright, Lisa A., Diver, W Ryan, Weiner, George J., Conde, Lucia, Bracci, Paige M., Riby, Jacques, Arnett, Donna K., Leach, Justin M., Holly, Elizabeth A., Benavente, Yolanda, Sala, Núria, Casabonne, Delphine, Becker, Nikolaus, Brennan, Paul, Foretova, Lenka, Maynadie, Marc, McKay, James, Staines, Anthony, Chaffee, Kari G., Achenbach, Sara J., Strom, Sara S., Leis, Jose F., Caporaso, Neil E., De Roos, Anneclaire J., Severson, Richard K., Kaaks, Rudolph, Weiderpass, Elisabete, Chirlaque, María- Dolores, Vermeulen, Roel C. H., Travis, Ruth C., Southey, Melissa C., Milne, Roger L., Albanes, Demetrius, Zheng, Tongzhang, Holford, Theodore R., Maria, Ann, Gascoyne, Randy D., Connors, Joseph M., Bertrand, Kimberly A., Giovannucci, Edward, Kraft, Peter, Kricker, Anne, Turner, Jenny, Ennas, Maria Grazia, Miligi, Lucia, Liang, Liming, Ma, Baoshan, Crouch, Simon, Park, Ju-Hyun, Chatterjee, Nilanjan, North, Kari E., Snowden, John A., Wright, Josh, Fraumeni, Joseph F., Offit, Kenneth, Wu, Xifeng, de Sanjose, Silvia, Cerhan, James R., Chanock, Stephen J., Rothman, Nathaniel, Slager, Susan L.

“…Chronic lymphocytic leukemia (CLL) is a common lymphoid malignancy with strong heritability. To further understand the genetic susceptibility for CLL and…”
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Effect of Sickle Cell Anemia Therapies on the Natural History of Growth and Puberty Patterns by Nagalapuram, Vishnu, Kulkarni, Varsha, Leach, Justin, Aban, Inmaculada, Sirigaddi, Krishnaveni, Lebensburger, Jeffrey D, Iyer, Pallavi

“…As pediatric patients with sickle cell anemia (SCA) have impaired growth and puberty patterns, we studied the effect of disease-modifying therapies on growth…”
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