Search Results - "Leach, CL"

Prophylaxis of Early Adrenal Insufficiency to Prevent Bronchopulmonary Dysplasia: A Multicenter Trial by Watterberg, Kristi L, Gerdes, Jeffrey S, Cole, Cynthia H, Aucott, Susan W, Thilo, Elizabeth H, Mammel, Mark C, Couser, Robert J, Garland, Jeffery S, Rozycki, Henry J, Leach, Corinne L, Backstrom, Conra, Shaffer, Michele L

“…Infants developing bronchopulmonary dysplasia (BPD) show decreased cortisol response to adrenocorticotropic hormone. A pilot study of low-dose hydrocortisone…”
Get full text

Lung deposition of hydrofluoroalkane-134a beclomethasone is greater than that of chlorofluorocarbon fluticasone and chlorofluorocarbon beclomethasone : a cross-over study in healthy volunteers by Leach, Chet L, Davidson, Patricia J, Hasselquist, Bruce E, Boudreau, Robert J

“…To compare the lung deposition of radiolabeled hydrofluoroalkane-134a beclomethasone dipropionate (HFA-BDP) with chlorofluorocarbon fluticasone propionate…”
Get more information

Improved airway targeting with the CFC-free HFA-beclomethasone metered-dose inhaler compared with CFC-beclomethasone by Leach, CL, Davidson, PJ, Boudreau, RJ

“…Hydrofluoroalkane-134a (HFA) beclomethasone dipropionate (BDP) was formulated in a metered-dose inhaler (MDI) to deliver a particle size of 1.1 microm compared…”
Get full text

Improved delivery of inhaled steroids to the large and small airways by Leach, C.L.

“…The reformulation of asthma medications with non-ozone depleting propellants such as hydrofluoroalkane-134a (HFA) has provided the opportunity to apply new…”
Get full text

Partial Liquid Ventilation with Perflubron in Premature Infants with Severe Respiratory Distress Syndrome by Leach, Corinne Lowe, Greenspan, Jay S, Rubenstein, S. David, Shaffer, Thomas H, Wolfson, Marla R, Jackson, J. Craig, DeLemos, Robert, Fuhrman, Bradley P

“…Surfactant therapy has substantially improved the survival of premature infants with respiratory distress syndrome 1 but is not uniformly effective…”
Get full text

Effect of Dose on Response to Adrenocorticotropin in Extremely Low Birth Weight Infants by Watterberg, Kristi L., Shaffer, Michele L., Garland, Jeffery S., Thilo, Elizabeth H., Mammel, Mark C., Couser, Robert J., Aucott, Susan W., Leach, Corinne L., Cole, Cynthia H., Gerdes, Jeffrey S., Rozycki, Henry J., Backstrom, Conra

“…Context: Various cosyntropin doses are used to test adrenal function in premature infants, without consensus on appropriate dose or adequate response…”
Get full text

Perfluorocarbon-associated gas exchange (partial liquid ventilation) in respiratory distress syndrome: a prospective, randomized, controlled study by Leach, C L, Fuhrman, B P, Morin, 3rd, F C, Rath, M G

“…To determine the efficacy of perfluorocarbon-associated gas exchange (partial liquid ventilation) in respiratory distress syndrome. Prospective, randomized,…”
Get more information

Partial liquid ventilation in premature lambs with respiratory distress syndrome: Efficacy and compatibility with exogenous surfactant by Leach, Corinne Lowe, Holm, Bruce, Morin, Frederick C., Fuhrman, Bradley P., Papo, Michele C., Steinhorn, David, Hernan, Lynn J.

“…Objective: To determine the efficacy of partial liquid ventilation (PLV) by means of a medical-grade perfluorochemical liquid, perflubron (LiquiVent), in…”
Get full text

Targeting inhaled steroids by Leach, C

“…Asthma is a disease of the entire respiratory tract and successful asthma therapy requires drug delivery throughout the large and small airways. The most…”
Get more information

Alternative propellant aerosol delivery systems by Smyth, Hugh D C, Leach, Chet L

“…The year 2006 represents the 50th anniversary of the pressurized metered dose inhaler. With most technologies, 50 years represents a significant time span for…”
Get more information

Partial liquid ventilation enhances surfactant phospholipid production by Steinhorn, David M, Leach, Corinne L, Fuhrman, Bradley P, Holm, Bruce A

“…OBJECTIVE To study the effect of partial liquid ventilation on phospholipid metabolism. DESIGN Prospective, controlled laboratory study. SETTING…”
Get full text

Perfluorocarbon-associated gas exchange in normal and acid-injured large sheep by Hernan, Lynn J, Fuhrman, Bradley P, Kaiser, Jr, Penfil, Scott, Foley, Christopher, Papo, Michele C, Leach, Corinne L

“…OBJECTIVESWe hypothesized thata) perfluorocarbon-associated gas exchange could be accomplished in normal large sheep; b) the determinants of gas exchange would…”
Get full text

Perfluorocarbon-associated gas exchange improves oxygenation, lung mechanics, and survival in a model of adult respiratory distress syndrome by Papo, Michele C, Paczan, Pamela R, Fuhrman, Bradley P, Steinhorn, David M, Hernan, Lynn J, Leach, Corinne L, Holm, Bruce A, Fisher, John E, Kahn, Beverly A

“…OBJECTIVETo compare the effectiveness of perfluorocarbon-associated gas exchange to volume controlled positive pressure breathing in supporting gas exchange,…”
Get full text

Perfluorocarbon-associated gas exchange in gastric aspiration by Nesti, F D, Fuhrman, B P, Steinhorn, D M, Papo, M C, Hernan, L J, Duffy, L C, Fisher, J E, Leach, C L, Paczan, P R, Burak, B A

“…To test whether perfluorocarbon-associated gas exchange (gas ventilation of the perfluorocarbon-liquid filled lung) could support oxygenation better than…”
Get more information

High-frequency partial liquid ventilation in respiratory distress syndrome: hemodynamics and gas exchange by Sukumar, Minakshi, Bommaraju, Mahesh, Fisher, John E, Morin III, Frederick C, Papo, Michele C, Fuhrman, Bradley P, Hernan, Lynn J, Leach, Corinne Lowe

“…Divisions of 1  Neonatology and 2  Critical Care, Department of Pediatrics, and 3  Department of Pathology, Children's Hospital of Buffalo, State University of…”
Get full text

Influence of particle size and patient dosing technique on lung deposition of HFA-beclomethasone from a metered dose inhaler by Leach, Chet L, Davidson, Patricia J, Hasselquist, Bruce E, Boudreau, Robert J

“…The objective of this study was to determine the lung delivery of HFA-134a-beclomethasone dipropionate (HFA-BDP) from a breath-activated inhaler (QVAR…”
Get more information

Pathophysiology of congenital diaphragmatic hernia. III: Exogenous surfactant therapy for the high-risk neonate with CDH by Glick, P L, Leach, C L, Besner, G E, Egan, E A, Morin, F C, Malanowska-Kantoch, A, Robinson, L K, Brody, A, Lele, A S, McDonnell, M

“…Exogenous surfactant therapy (EST) in surfactant-deficient premature infants has been shown to improve lung compliance, decrease morbidity, and improve…”
Get more information

Regional pulmonary blood flow during partial liquid ventilation in normal and acute oleic acid-induced lung-injured piglets by Enrione, Maria A, Papo, Michele C, Leach, Corinne L, Holm, Bruce A, Hernan, Lynn J, Fuhrman, Bradley P, Dowhy, Mark S, Rath, Mark G, Frisicaro, Paul E

“…OBJECTIVE:To determine the spatial distribution of pulmonary blood flow in three groups of pigletspartial liquid ventilation in normal piglets, partial liquid…”
Get full text

Ductus venosus flow velocity in newborn lambs during increased pulmonary artery pressure by FUGELSETH, D, LEACH, C. L, MORIN, F. C, LIESTØL, K, HUMAEI WANG, SWARTZ, D, LINDEMANN, R

“…The aim of the present study was to assess with ultrasound the ductus venosus flow velocity in newborn lambs with increasing pulmonary artery pressures and to…”
Get full text

Prolonged studies of perfluorocarbon associated gas exchange and of the resumption of conventional mechanical ventilation by Salman, Najmul H, Fuhrman, Bradley P, Steinhorn, David M, Papo, Michele C, Hernan, Lynn J, Leach, Corinne L, Fischer, John E

“…OBJECTIVETo determine whether oxygenation and lung mechanics are preserved during perfluorocarbon associated gas exchange of 24 hrs duration and after…”
Get full text