Search Results - "Leach, A"

Effect of climate change on vector-borne disease risk in the UK by Medlock, Jolyon M, Dr, Leach, Steve A, PhD

“…Summary During the early part of the 21st century, an unprecedented change in the status of vector-borne disease in Europe has occurred. Invasive mosquitoes…”
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Sugar Transporters in Plants: New Insights and Discoveries by Julius, Benjamin T, Leach, Kristen A, Tran, Thu M, Mertz, Rachel A, Braun, David M

“…Carbohydrate partitioning is the process of carbon assimilation and distribution from source tissues, such as leaves, to sink tissues, such as stems, roots and…”
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A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance by Chauhan, Dharminder, Tian, Ze, Nicholson, Benjamin, Kumar, K.G. Suresh, Zhou, Bin, Carrasco, Ruben, McDermott, Jeffrey L., Leach, Craig A., Fulcinniti, Mariaterresa, Kodrasov, Matthew P., Weinstock, Joseph, Kingsbury, William D., Hideshima, Teru, Shah, Parantu K., Minvielle, Stephane, Altun, Mikael, Kessler, Benedikt M., Orlowski, Robert, Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth C.

“…Bortezomib therapy has proven successful for the treatment of relapsed/refractory, relapsed, and newly diagnosed multiple myeloma (MM); however, dose-limiting…”
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The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells by Leach, D. A., Mohr, A., Giotis, E. S., Cil, E., Isac, A. M., Yates, L. L., Barclay, W. S., Zwacka, R. M., Bevan, C. L., Brooke, G. N.

“…SARS-CoV-2 attacks various organs, most destructively the lung, and cellular entry requires two host cell surface proteins: ACE2 and TMPRSS2. Downregulation of…”
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Winter stream temperature in the rain-on-snow zone of the Pacific Northwest: influences of hillslope runoff and transient snow cover by Leach, J. A, Moore, R. D

“…Stream temperature dynamics during winter are less well studied than summer thermal regimes, but the winter season thermal regime can be critical for fish…”
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Thermal detection of discrete riparian inflow points (DRIPs) during contrasting hydrological events by Ploum, Stefan W., Leach, Jason A., Kuglerová, Lenka, Laudon, Hjalmar

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TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis by Gregory, Adam P., Dendrou, Calliope A., Attfield, Kathrine E., Haghikia, Aiden, Xifara, Dionysia K., Butter, Falk, Poschmann, Gereon, Kaur, Gurman, Lambert, Lydia, Leach, Oliver A., Prömel, Simone, Punwani, Divya, Felce, James H., Davis, Simon J., Gold, Ralf, Nielsen, Finn C., Siegel, Richard M., Mann, Matthias, Bell, John I., McVean, Gil, Fugger, Lars

“…Genome-wide association studies in combination with functional analyses identify a genetic variant that explains why anti-tumour necrosis factor therapy, used…”
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Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity by Dendrou, Calliope A, Cortes, Adrian, Shipman, Lydia, Evans, Hayley G, Attfield, Kathrine E, Jostins, Luke, Barber, Thomas, Kaur, Gurman, Kuttikkatte, Subita Balaram, Leach, Oliver A, Desel, Christiane, Faergeman, Soren L, Cheeseman, Jane, Neville, Matt J, Sawcer, Stephen, Compston, Alastair, Johnson, Adam R, Everett, Christine, Bell, John I, Karpe, Fredrik, Ultsch, Mark, Eigenbrot, Charles, McVean, Gil, Fugger, Lars

“…Thousands of genetic variants have been identified, which contribute to the development of complex diseases, but determining how to elucidate their biological…”
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Genome assembly and population genomic analysis provide insights into the evolution of modern sweet corn by Hu, Ying, Colantonio, Vincent, Müller, Bárbara S. F., Leach, Kristen A., Nanni, Adalena, Finegan, Christina, Wang, Bo, Baseggio, Matheus, Newton, Carter J., Juhl, Emily M., Hislop, Lillian, Gonzalez, Juan M., Rios, Esteban F., Hannah, L. Curtis, Swarts, Kelly, Gore, Michael A., Hennen-Bierwagen, Tracie A., Myers, Alan M., Settles, A. Mark, Tracy, William F., Resende, Marcio F. R.

“…Sweet corn is one of the most important vegetables in the United States and Canada. Here, we present a de novo assembly of a sweet corn inbred line Ia453 with…”
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p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells by Periyasamy, Manikandan, Singh, Anup K, Gemma, Carolina, Kranjec, Christian, Farzan, Raed, Leach, Damien A, Navaratnam, Naveenan, Pálinkás, Hajnalka L, Vértessy, Beata G, Fenton, Tim R, Doorbar, John, Fuller-Pace, Frances, Meek, David W, Coombes, R Charles, Buluwela, Laki, Ali, Simak

“…Cancer genome sequencing has implicated the cytosine deaminase activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide-like (APOBEC) genes as an…”
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Evaluating topography‐based predictions of shallow lateral groundwater discharge zones for a boreal lake‐stream system by Leach, J. A., Lidberg, W., Kuglerová, L., Peralta‐Tapia, A., Ågren, A., Laudon, H.

“…Groundwater discharge along streams exerts an important influence on biogeochemistry and thermal regimes of aquatic ecosystems. A common approach for…”
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Cost-effective operating strategy for residential micro-combined heat and power by Hawkes, A.D., Leach, M.A.

“…It is commonly assumed that dispatch of micro-combined heat and power (micro-CHP) should be heat driven, where the unit turns on when a heat load is present,…”
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Identification of transcription factor co-regulators that drive prostate cancer progression by Siddappa, Manjunath, Wani, Sajad A., Long, Mark D., Leach, Damien A., Mathé, Ewy A., Bevan, Charlotte L., Campbell, Moray J.

“…In prostate cancer (PCa), and many other hormone-dependent cancers, there is clear evidence for distorted transcriptional control as disease driver mechanisms…”
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SWEET as Sugar： New Sucrose Effluxers in Plants by Frank Baker, R., Leach, Kristen A., Braun, David M.

“…Photosynthesis leads to the fixation of carbon in leaves and to the accumulation of carbohydrates （e.g., sucrose, starch）. This assimilated carbon must be…”
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Assessment of lameness prevalence and associated risk factors in dairy herds in England and Wales by Barker, Z E, Leach, K A, Whay, H R, Bell, N J, Main, D C J

“…Visits were made to 205 dairy farms in England and Wales between October 2006 and May 2007 by 1 or more of 4 researchers. At each visit, all milking cows were…”
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Deformation of Top-Down and Bottom-Up Silver Nanowires by Leach, A. M., McDowell, M., Gall, K.

“…Atomistic simulations are employed to probe the deformation behavior of experimentally observed top‐down and bottom‐up face‐centered cubic silver nanowires…”
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Headwater lakes and their influence on downstream discharge by Leach, Jason A., Laudon, Hjalmar

“…Small headwater lakes are common water features in northern environments. These small lakes are often reported to have an influence on downstream water…”
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A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer by Fletcher, C E, Deng, L, Orafidiya, F, Yuan, W, Lorentzen, M P G S, Cyran, O W, Varela-Carver, A, Constantin, T A, Leach, D A, Dobbs, F M, Figueiredo, I, Gurel, B, Parkes, E, Bogdan, D, Pereira, R R, Zhao, S G, Neeb, A, Issa, F, Hester, J, Kudo, H, Liu, Y, Philippou, Y, Bristow, R, Knudsen, K, Bryant, R J, Feng, F Y, Reed, S H, Mills, I G, de Bono, J, Bevan, C L

“…miR-346 was identified as an activator of Androgen Receptor (AR) signalling that associates with DNA damage response (DDR)-linked transcripts in prostate…”
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AMPK activation protects against prostate cancer by inducing a catabolic cellular state by Penfold, Lucy, Woods, Angela, Pollard, Alice E., Arizanova, Julia, Pascual-Navarro, Eneko, Muckett, Phillip J., Dore, Marian H., Montoya, Alex, Whilding, Chad, Fets, Louise, Mokochinski, Joao, Constantin, Theodora A., Varela-Carver, Anabel, Leach, Damien A., Bevan, Charlotte L., Nikitin, Alexander Yu, Hall, Zoe, Carling, David

“…Emerging evidence indicates that metabolic dysregulation drives prostate cancer (PCa) progression and metastasis. AMP-activated protein kinase (AMPK) is a…”
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The Ubiquitin-Specific Protease USP34 Regulates Axin Stability and Wnt/β-Catenin Signaling by Lui, Tony T. H., Lacroix, Celine, Ahmed, Syed M., Goldenberg, Seth J., Leach, Craig A., Daulat, Avais M., Angers, Stephane

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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