Search Results - "Lea, Robert W"

Circulating MicroRNA Biomarkers for Glioma and Predicting Response to Therapy by Tumilson, Charlotte A., Lea, Robert W., Alder, Jane E., Shaw, Lisa

“…The need for glioma biomarkers with improved sensitivity and specificity has sparked research into short non-coding RNA known as microRNA (miRNA). Altered…”
Get full text

Investigating the rapid diagnosis of gliomas from serum samples using infrared spectroscopy and cytokine and angiogenesis factors by Hands, James R., Abel, Peter, Ashton, Katherine, Dawson, Timothy, Davis, Charles, Lea, Robert W, McIntosh, Alastair J S, Baker, Matthew J

“…The ability to diagnose brain cancer rapidly from serum samples is of great interest; such a diagnosis would allow for rapid testing and time to results…”
Get full text

Effects of orally administered lavender essential oil on responses to anxiety-provoking film clips by Bradley, Belinda F., Brown, Stephen L., Chu, Simon, Lea, Robert W.

“…Background Lavender odour is commonly used to alleviate mild anxiety. Double blind studies are difficult to conduct with odours, and there are few reliable…”
Get full text

Brain tumour differentiation: rapid stratified serum diagnostics via attenuated total reflection Fourier-transform infrared spectroscopy by Hands, James R., Clemens, Graeme, Stables, Ryan, Ashton, Katherine, Brodbelt, Andrew, Davis, Charles, Dawson, Timothy P., Jenkinson, Michael D., Lea, Robert W., Walker, Carol, Baker, Matthew J.

“…The ability to diagnose cancer rapidly with high sensitivity and specificity is essential to exploit advances in new treatments to lead significant reductions…”
Get full text

Characterization of the Lipid Profile in Dementia and Depression in the Elderly by Dimopoulos, Nikolaos, Piperi, Christina, Salonicioti, Aristea, Psarra, Vassiliki, Mitsonis, Charalampos, Liappas, Ioannis, Lea, Robert W., Kalofoutis, Anastasios

“…The purpose of the study was to examine the association of plasma lipid concentrations with changes in cognitive function and depressive states in elderly…”
Get full text

Increased plasma levels of 8- iso -PGF2α and IL-6 in an elderly population with depression by Dimopoulos, Nikolaos, Piperi, Christina, Psarra, Vassiliki, Lea, Robert W, Kalofoutis, Anastasios

“…Abstract Oxidative damage and immune–inflammatory activation have been suggested to play a role in depression. The purpose of the study was to investigate…”
Get full text

Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR) spectral discrimination of brain tumour severity from serum samples by Hands, James R., Dorling, Konrad M., Abel, Peter, Ashton, Katherine M., Brodbelt, Andrew, Davis, Charles, Dawson, Timothy, Jenkinson, Michael D., Lea, Robert W., Walker, Carol, Baker, Matthew J.

“…Gliomas are the most frequent primary brain tumours in adults with over 9,000 people diagnosed each year in the UK. A rapid, reagent‐free and cost‐effective…”
Get full text

Effect of substrate choice and tissue type on tissue preparation for spectral histopathology by Raman microspectroscopy by Fullwood, Leanne M, Griffiths, Dave, Ashton, Katherine, Dawson, Timothy, Lea, Robert W, Davis, Charles, Bonnier, Franck, Byrne, Hugh J, Baker, Matthew J

“…Raman spectroscopy is a non-destructive, non-invasive, rapid and economical technique which has the potential to be an excellent method for the diagnosis of…”
Get more information

Growth hormone and cancer: GH production and action in glioma? by Lea, Robert W, Dawson, Timothy, Martinez-Moreno, Carlos G, El-Abry, Nasra, Harvey, Steve

“…Highlights • GH- and GH receptor immunoreactivity was co-localized in cytoplasmic but not nuclear compartment of glioma. • Glioma differs from most cancers in…”
Get full text

Association of Cognitive Impairment with Plasma Levels of Folate, Vitamin B12 and Homocysteine in the Elderly by Dimopoulos, Nikolaos, Piperi, Christina, Salonicioti, Aristea, Psarra, Vassiliki, Gazi, Flerri, Nounopoulos, Charalambos, Lea, Robert W, Kalofoutis, Anastasios

“…Background: Alterations in folate, vitamin B 12 and homocysteine plasma levels have been associated with aging, neuronal development and cognitive impairment…”
Get full text

Cn-AMP2 from green coconut water is an anionic anticancer peptide by Prabhu, Saurabh, Dennison, Sarah R., Mura, Manuela, Lea, Robert W., Snape, Timothy J., Harris, Frederick

“…Globally, death due to cancers is likely to rise to over 20 million by 2030, which has created an urgent need for novel approaches to anticancer therapies such…”
Get full text

Correlation of folate, vitamin B12 and homocysteine plasma levels with depression in an elderly Greek population by Dimopoulos, Nikolaos, Piperi, Christina, Salonicioti, Aristea, Psarra, Vassiliki, Gazi, Flerri, Papadimitriou, Alexandros, Lea, Robert W, Kalofoutis, Anastasios

“…Alterations in folate, vitamin B12 and homocysteine plasma levels have been associated with aging, neuronal development and depressive symptomatology…”
Get full text

Application of the ELISPOT method for comparative analysis of interleukin (IL)-6 and IL-10 secretion in peripheral blood of patients with astroglial tumors by Samaras, Vassilis, Piperi, Christina, Korkolopoulou, Penelope, Zisakis, Athanasios, Levidou, Georgia, Themistocleous, Marios S, Boviatsis, Efstathios I, Sakas, Damianos E, Lea, Robert W, Kalofoutis, Anastasios, Patsouris, Efstratios

“…Glioblastoma, (grade IV astrocytoma), is characterized by rapid growth and resistance to treatment. Identification of markers of aggressiveness in this tumor…”
Get full text

Comparative analysis of peripheral and localised cytokine secretion in glioblastoma patients by Zisakis, Athanasios, Piperi, Christina, Themistocleous, Marios S., Korkolopoulou, Penelope, Boviatsis, Efstathios I., Sakas, Damianos E., Patsouris, Efstratios, Lea, Robert W., Kalofoutis, Anastasios

“…Background: Malignant gliomas are the most common primary brain tumours of both children and adults. The unique aspects of their biology and anatomic site…”
Get full text

Analysis of interleukin (IL)-8 expression in human astrocytomas: Associations with IL-6, cyclooxygenase-2, vascular endothelial growth factor, and microvessel morphometry by Samaras, Vassilis, Piperi, Christina, Levidou, Georgia, Zisakis, Athanasios, Kavantzas, Nikolaos, Themistocleous, Marios S, Boviatsis, Efstathios I, Barbatis, Calypso, Lea, Robert W, Kalofoutis, Anastasios, Korkolopoulou, Penelope

“…Abstract Malignant astrocytomas are highly vascular neoplasms with potent angiogenic activity. The present study aimed to investigate peripheral and local…”
Get full text

Elevation of plasma concentration of adhesion molecules in late-life depression by Dimopoulos, Nikolaos, Piperi, Christina, Salonicioti, Aristea, Mitsonis, Charalampos, Liappas, Ioannis, Lea, Robert W., Kalofoutis, Anastasios

“…Objectives Late‐life depression may be associated with vascular disease. The purpose of the study was to investigate this association by determining the levels…”
Get full text

Indices of low-grade chronic inflammation correlate with early cognitive deterioration in an elderly Greek population by Dimopoulos, Nikolaos, Piperi, Christina, Salonicioti, Aristea, Mitropoulos, Panagiotis, Kallai, Eleni, Liappas, Ioannis, Lea, Robert W., Kalofoutis, Anastasios

“…Elevated serum levels of adhesion molecules (AM) reflect low-grade chronic inflammation and have been associated with several conditions of neuronal damage…”
Get full text

Effect of melatonin on phagocytic activity and intracellular free calcium concentration in testicular macrophages from normal and streptozotocin-induced diabetic rats by Pawlak, Joanna, Singh, Jaipaul, Lea, Robert W, Skwarlo-Sonta, Krystyna

“…This study examined the effect of melatonin (MLT) on in vitro phagocytosis of testicular macrophages taken from control and streptozotocin (STZ)-induced…”
Get full text

Neurosteroid biosynthesis in vertebrate brains by Tsutsui, Kazuyoshi, Ukena, Kazuyoshi, Takase, Minoru, Kohchi, Chie, Lea, Robert W

“…In mammals, neurosteroids are now known to be synthesized de novo in the brain as well as other areas of the nervous system through mechanisms at least partly…”
Get full text

Changes in central steroid receptor expression, steroid synthesis, and dopaminergic activity related to the reproductive cycle of the ring dove by Lea, Robert W., Clark, Judith A., Tsutsui, Kazuyoshi

“…This review examines possible neural mechanisms involved in the expression of parental behavior in the ring dove, Streptopelia risoria. This avian species has…”
Get full text