Search Results - "Lea, R. G."

Dietary omega-3 and -6 polyunsaturated fatty acids affect the composition and development of sheep granulosa cells, oocytes and embryos by Wonnacott, K E, Kwong, W Y, Hughes, J, Salter, A M, Lea, R G, Garnsworthy, P C, Sinclair, K D

“…The evidence that omega-3 (n-3) and -6 (n-6) polyunsaturated fatty acids (PUFAs) have differential effects on ovarian function, oocytes and embryo quality is…”
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Leptin expression in placental and fetal tissues: does leptin have a functional role? by Hoggard, N, Haggarty, P, Thomas, L, Lea, R G

“…Leptin is expressed in the placenta and in certain fetal tissues; however, little is known with regard to the function of this hormone in these tissues. To…”
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Placental leptin in normal, diabetic and fetal growth-retarded pregnancies by Lea, R.G., Howe, D., Hannah, L.T., Bonneau, O., Hunter, L., Hoggard, N.

“…Leptin expression in third trimester placenta (p) and leptin concentrations in umbilical cord blood (cb) were investigated in normal pregnancies [n = 10 (p),…”
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Effect of maternal undernutrition during pregnancy on early ovarian development and subsequent follicular development in sheep fetuses by Rae, MT, Palassio, S, Kyle, CE, Brooks, AN, Lea, RG, Miller, DW, Rhind, SM

“…Gonad development in female sheep fetuses is thought to occur in a number of key stages. The aim of this study was to determine the effects of maternal…”
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Effects of maternal undernutrition during early pregnancy on apoptosis regulators in the ovine fetal ovary by Lea, R G, Andrade, L P, Rae, M T, Hannah, L T, Kyle, C E, Murray, J F, Rhind, S M, Miller, D W

“…This study aimed to determine whether reduced fetal ovary folliculogenesis in ewes undernourished during early/midpregnancy is associated with altered ovarian…”
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Effect of iron deficiency on placental transfer of iron and expression of iron transport proteins in vivo and in vitro by Gambling, L, Danzeisen, R, Gair, S, Lea, R G, Charania, Z, Solanky, N, Joory, K D, Srai, S K, McArdle, H J

“…Maternal iron deficiency during pregnancy induces anaemia in the developing fetus; however, the severity tends to be less than in the mother. The mechanism…”
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Role of inflammatory mediators in human endometrium during progesterone withdrawal and early pregnancy by CRITCHLEY, H. O. D, JONES, R. L, LEA, R. G, DRUDY, T. A, KELLY, R. W, WILLIAMS, A. R. W, BAIRD, D. T

“…The role of progesterone (P4) in the regulation of inflammatory mediators interleukin-8 (IL-8), monocyte chemoattractant protein-1, and cyclooxygenase-2…”
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Effects of Exposure to Environmental Chemicals During Pregnancy on the Development of the Male and Female Reproductive Axes by Bellingham, M, Fiandanese, N, Byers, A, Cotinot, C, Evans, NP, Pocar, P, Amezaga, MR, Lea, RG, Sinclair, KD, Rhind, SM, Fowler, PA

“…There is a large body of literature describing effects of environmental chemicals (ECs), many of them anthropogenic with endocrine‐disrupting properties, on…”
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The immunolocalization of bcl-2 at the maternal-fetal interface in healthy and failing pregnancies by Lea, R G, al-Sharekh, N, Tulppala, M, Critchley, H O

“…Programmed cell death by apoptosis occurs in both fetal and maternal tissues during early pregnancy. To investigate a role for apoptosis at the maternal-fetal…”
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Sex steroid regulation of leukocyte traffic in human decidua by CRITCHLEY, H. O. D, KELLY, R. W, LEA, R. G, DRUDY, T. A, JONES, R. L, BAIRD, D. T

“…Endometrial leukocyte subpopulations vary over the reproductive cycle, but no data exist on the mechanism regulating their recruitment into uterine tissue…”
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SOCS genes expression during physiological and perturbed implantation in bovine endometrium by Vitorino Carvalho, A, Reinaud, P, Forde, N, Healey, G D, Eozenou, C, Giraud-Delville, C, Mansouri-Attia, N, Gall, L, Richard, C, Lonergan, P, Sheldon, I M, Lea, R G, Sandra, O

“…In mammals, suppressor of cytokine signalling (CISH, SOCS1 to SOCS7) factors control signalling pathways involved in the regulation of numerous physiological…”
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Deficient syncytiotrophoblast tumour necrosis factor-alpha characterizes failing first trimester pregnancies in a subgroup of recurrent miscarriage patients by Lea, R G, Tulppala, M, Critchley, H O

“…Pregnancy failure in mice has been associated with increased placental concentrations of the pro-inflammatory cytokine tumour necrosis factor-alpha…”
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Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor beta 1 gene (TGF beta 1) by Ohno, I, Lea, R G, Flanders, K C, Clark, D A, Banwatt, D, Dolovich, J, Denburg, J, Harley, C B, Gauldie, J, Jordana, M

“…Transforming growth factor beta (TGF beta) is a multifunctional protein which has been suggested to play a central role in the pathogenesis of chronic…”
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Prostaglandins and menstruation by Baird, David T., Cameron, S.T., Critchley, H.O.D., Drudy, T.A., Howe, A., Jones, R.L., Lea, R.G., Kelly, R.W.

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Novel gonadal characteristics in an aged bovine freemartin by Remnant, J.G., Lea, R.G., Allen, C.E., Huxley, J.N., Robinson, R.S., Brower, A.I.

“…The gonads from a five-year-old freemartin Holstein animal were subjected to morphological analysis and to immunohistochemistry using antibodies against…”
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Environment and reproductive dysfunction in captive female great apes (Hominidae) by Bolton, R. L., Masters, N. J., Milham, P., Lea, R. G.

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The Effect of Ceruloplasmin on Iron Release from Placental (BeWo) Cells; Evidence for an Endogenous Cu Oxidase by Danzeisen, R., Ponnambalam, S., Lea, R.G., Page, K., Gambling, L., McArdle, H.J.

“…The mechanism of iron release from the placenta into the fetal circulation is not well understood. Ceruloplasmin, a plasma ferroxidase, has been implicated in…”
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Cytokines and the Regulation of Apoptosis in Reproductive Tissues: A Review by Lea, Richard G., Riley, Simon C., Antipatis, Christos, Hannah, Lisa, Ashworth, Cheryl J., Clark, David A., Critchley, Hilary O.D.

“…PROBLEM: To determine the role of apoptosis‐regulating genes bax and bcl‐2 in reproduction. METHOD OF STUDY: Review of literature and current data. RESULTS:…”
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Disturbed development of the preimplantation embryo in the insulin-dependent diabetic BB/E rat by Lea, R. G., McCracken, J. E., McIntyre, S. S., Smith, W., Baird, J. D.

“…Disturbed development of the preimplantation embryo in the insulin-dependent diabetic BB/E rat. R G Lea , J E McCracken , S S McIntyre , W Smith and J D Baird…”
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Effects of environmental pollutants on the reproduction and welfare of ruminants by Rhind, S. M., Evans, N. P., Bellingham, M., Sharpe, R. M., Cotinot, C., Mandon-Pepin, B., Loup, B., Sinclair, K. D., Lea, R. G., Pocar, P., Fischer, B., van der Zalm, E., Hart, K., Schmidt, J.-S., Amezaga, M. R., Fowler, P. A.

“…Anthropogenic pollutants comprise a wide range of synthetic organic compounds and heavy metals, which are dispersed throughout the environment, usually at low…”
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