Search Results - "LeBlanc, Scott E"

Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cells by Wu, Qiong, Sharma, Soni, Cui, Hang, LeBlanc, Scott E, Zhang, Hong, Muthuswami, Rohini, Nickerson, Jeffrey A, Imbalzano, Anthony N

“…Brahma related gene product 1 (BRG1) is an ATPase that drives the catalytic activity of a subset of the mammalian SWI/SNF chromatin remodeling enzymes. BRG1 is…”
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Protein Arginine Methyltransferase 5 (Prmt5) Promotes Gene Expression of Peroxisome Proliferator-Activated Receptor γ2 (PPARγ2) and Its Target Genes during Adipogenesis by LeBlanc, Scott E, Konda, Silvana, Wu, Qiong, Hu, Yu-Jie, Oslowski, Christine M, Sif, Saïd, Imbalzano, Anthony N

“…Regulation of adipose tissue formation by adipogenic-regulatory proteins has long been a topic of interest given the ever-increasing health concerns of obesity…”
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Neuropathy-Associated Egr2 Mutants Disrupt Cooperative Activation of Myelin Protein Zero by Egr2 and Sox10 by LeBlanc, Scott E., Ward, Rebecca M., Svaren, John

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The PPARγ locus makes long-range chromatin interactions with selected tissue-specific gene loci during adipocyte differentiation in a protein kinase A dependent manner by LeBlanc, Scott E, Wu, Qiong, Barutcu, A Rasim, Xiao, Hengyi, Ohkawa, Yasuyuki, Imbalzano, Anthony N

“…Differentiation signaling results in reprogramming of cellular gene expression that leads to morphological changes and functional specialization of a precursor…”
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Direct Regulation of Myelin Protein Zero Expression by the Egr2 Transactivator by LeBlanc, Scott E., Jang, Sung-Wook, Ward, Rebecca M., Wrabetz, Lawrence, Svaren, John

“…During myelination of the peripheral nervous system, the myelin protein zero (Mpz) gene is induced to produce the most abundant protein component (P0) of…”
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Chromatin accessibility and transcription factor binding at the PPARγ2 promoter during adipogenesis is protein kinase A-dependent by Xiao, Hengyi, LeBlanc, Scott E., Wu, Qiong, Konda, Silvana, Salma, Nunciada, Marfella, Concetta G.A., Ohkawa, Yasuyuki, Imbalzano, Anthony N.

“…The nuclear hormone receptor peroxisome proliferator‐activated receptor gamma (PPARγ) is a ligand‐activated transcription factor that specifies formation of…”
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In vivo detection of Egr2 binding to target genes during peripheral nerve myelination by Jang, Sung‐Wook, LeBlanc, Scott E., Roopra, Avtar, Wrabetz, Lawrence, Svaren, John

“…Egr2/Krox20 is a zinc finger transactivator that regulates a diverse array of genes required for peripheral nerve myelination. Although several studies have…”
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Regulation of cholesterol/lipid biosynthetic genes by Egr2/Krox20 during peripheral nerve myelination by LeBlanc, Scott E., Srinivasan, Rajini, Ferri, Cinzia, Mager, Gennifer M., Gillian‐Daniel, Anne Lynn, Wrabetz, Lawrence, Svaren, John

“…Myelination of peripheral nerves by Schwann cells requires a large amount of lipid and cholesterol biosynthesis. To understand the transcriptional coordination…”
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Promoter-enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase by LeBlanc, Scott E, Wu, Qiong, Lamba, Pallavi, Sif, Saïd, Imbalzano, Anthony N

“…PPARγ2 is a critical lineage-determining transcription factor that is essential for adipogenic differentiation. Here we report characterization of the…”
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Promoter-enhancer looping at the PPAR gamma 2 locus during adipogenic differentiation requires the Prmt5 methyltransferase by LeBlanc, Scott E, Wu, Qiong, Lamba, Pallavi, Sif, Said, Imbalzano, Anthony N

“…PPAR gamma 2 is a critical lineage-determining transcription factor that is essential for adipogenic differentiation. Here we report characterization of the…”
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Protein Arginine Methyltransferase 5 (Prmt5) Promotes Gene Expression of Peroxisome Proliferator-Activated Receptor gamma 2 (PPAR gamma 2) and Its Target Genes during Adipogenesis by LeBlanc, Scott E, Konda, Silvana, Wu, Qiong, Hu, Yu-Jie, Oslowski, Christine M, Sif, Saied, Imbalzano, Anthony N

“…Regulation of adipose tissue formation by adipogenic-regulatory proteins has long been a topic of interest given the ever-increasing health concerns of obesity…”
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Cbl-b regulates antigen-induced TCR down-regulation and IFN-gamma production by effector CD8 T cells without affecting functional avidity by Shamim, Mohammed, Nanjappa, Som G, Singh, Anju, Plisch, Erin Hemmila, LeBlanc, Scott E, Walent, Jane, Svaren, John, Seroogy, Christine, Suresh, M

“…The E3 ubiquitin ligase Cbl-b is a negative regulator of TCR signaling that: 1) sets the activation threshold for T cells; 2) is induced in anergic T cells;…”
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A mutation in the mouse Chd2 chromatin remodeling enzyme results in a complex renal phenotype by Marfella, Concetta G A, Henninger, Nils, LeBlanc, Scott E, Krishnan, Namrata, Garlick, David S, Holzman, Lawrence B, Imbalzano, Anthony N

“…Glomerular diseases are the third leading cause of kidney failure worldwide, behind only diabetes and hypertension. The molecular mechanisms underlying the…”
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The PPAR[gamma] Locus Makes Long-Range Chromatin Interactions with Selected Tissue-Specific Gene Loci during Adipocyte Differentiation in a Protein Kinase A Dependent Manner by LeBlanc, Scott E, Wu, Qiong, Barutcu, A. Rasim, Xiao, Hengyi, Ohkawa, Yasuyuki, Imbalzano, Anthony N

“…Differentiation signaling results in reprogramming of cellular gene expression that leads to morphological changes and functional specialization of a precursor…”
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Locus‐wide Regulation of Mpz Expression by Egr2 and Sox10 by Jang, Sung‐Wook, LeBlanc, Scott E, Jones, Erin A, Svaren, John

“…Abstract only The Egr2/Krox20 transcription factor is a master regulator of the myelination program in peripheral nerve. We have recently demonstrated that…”
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The PPAR gamma Locus Makes Long-Range Chromatin Interactions with Selected Tissue-Specific Gene Loci during Adipocyte Differentiation in a Protein Kinase A Dependent Manner: e86140 by LeBlanc, Scott E, Wu, Qiong, Barutcu, A Rasim, Xiao, Hengyi, Ohkawa, Yasuyuki, Imbalzano, Anthony N

“…Differentiation signaling results in reprogramming of cellular gene expression that leads to morphological changes and functional specialization of a precursor…”
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Transcription factor interactions in the regulation of myelin gene expression by LeBlanc, Scott E

“…Myelination of the peripheral nervous system requires the activation of a genetic network in Schwann cells, coordinately regulating the expression of both…”
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Cbl-b Regulates Antigen-Induced TCR Down-Regulation and IFN-{gamma} Production by Effector CD8 T Cells without Affecting Functional Avidity by Shamim, Mohammed, Nanjappa, Som G, Singh, Anju, Plisch, Erin Hemmila, LeBlanc, Scott E, Walent, Jane, Svaren, John, Seroogy, Christine, Suresh, M

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