Search Results - "LeBlanc, Michelle"

Domain-specific control of germ cell polarity and migration by multifunction Tre1 GPCR by LeBlanc, Michelle G, Lehmann, Ruth

“…The migration of primordial germ cells (PGCs) from their place of origin to the embryonic gonad is an essential reproductive feature in many animal species. In…”
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Finding their way: themes in germ cell migration by Barton, Lacy J, LeBlanc, Michelle G, Lehmann, Ruth

“…Embryonic germ cell migration is a vital component of the germline lifecycle. The translocation of germ cells from the place of origin to the developing…”
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Common and rare variant associations with clonal haematopoiesis phenotypes by Kessler, Michael D., Damask, Amy, O’Keeffe, Sean, Banerjee, Nilanjana, Li, Dadong, Watanabe, Kyoko, Marketta, Anthony, Van Meter, Michael, Semrau, Stefan, Horowitz, Julie, Tang, Jing, Kosmicki, Jack A., Rajagopal, Veera M., Zou, Yuxin, Houvras, Yariv, Ghosh, Arkopravo, Gillies, Christopher, Mbatchou, Joelle, White, Ryan R., Verweij, Niek, Bovijn, Jonas, Parikshak, Neelroop N., LeBlanc, Michelle G., Jones, Marcus, Glass, David J., Lotta, Luca A., Cantor, Michael N., Atwal, Gurinder S., Locke, Adam E., Ferreira, Manuel A. R., Deering, Raquel, Paulding, Charles, Shuldiner, Alan R., Thurston, Gavin, Ferrando, Adolfo A., Salerno, Will, Reid, Jeffrey G., Overton, John D., Marchini, Jonathan, Kang, Hyun M., Baras, Aris, Abecasis, Gonçalo R., Jorgenson, Eric

“…Clonal haematopoiesis involves the expansion of certain blood cell lineages and has been associated with ageing and adverse health outcomes 1 – 5 . Here we use…”
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Secretogranin III: a diabetic retinopathy-selective angiogenic factor by Li, Wei, Webster, Keith A., LeBlanc, Michelle E., Tian, Hong

“…Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an…”
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Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy by LeBlanc, Michelle E, Wang, Weiwen, Chen, Xiuping, Caberoy, Nora B, Guo, Feiye, Shen, Chen, Ji, Yanli, Tian, Hong, Wang, Hui, Chen, Rui, Li, Wei

“…Diabetic retinopathy (DR) is a leading cause of vision loss with retinal vascular leakage and/or neovascularization. Current antiangiogenic therapy against…”
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Glycocalyx regulation of vascular endothelial growth factor receptor 2 activity by Leblanc, Michelle E., Saez‐Torres, Kahira L., Cano, Issahy, Hu, Zhengping, Saint‐Geniez, Magali, Ng, Yin‐Shan, D'Amore, Patricia A.

“…ABSTRACT We have previously shown that knockdown of endomucin (EMCN), an integral membrane glycocalyx glycoprotein, prevents VEGF‐induced proliferation,…”
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ADAM10 and ADAM17 proteases mediate proinflammatory cytokine-induced and constitutive cleavage of endomucin from the endothelial surface by Yang, Jinling, LeBlanc, Michelle E., Cano, Issahy, Saez-Torres, Kahira L., Saint-Geniez, Magali, Ng, Yin-Shan, D'Amore, Patricia A.

“…Contact between inflammatory cells and endothelial cells (ECs) is a crucial step in vascular inflammation. Recently, we demonstrated that the cell-surface…”
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Secretogranin III as a novel target for the therapy of choroidal neovascularization by LeBlanc, Michelle E., Wang, Weiwen, Ji, Yanli, Tian, Hong, Liu, Dachuan, Zhang, Xuxiang, Li, Wei

“…Wet age-related macular degeneration (AMD) with choroidal neovascularization (CNV) is a leading cause of vision loss in the elderly. The advent of…”
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Anti-secretogranin III therapy of oxygen-induced retinopathy with optimal safety by Tang, Fen, LeBlanc, Michelle E., Wang, Weiwen, Liang, Dan, Chen, Ping, Chou, Tsung-Han, Tian, Hong, Li, Wei

“…Retinopathy of prematurity (ROP) with pathological retinal neovascularization is the most common cause of blindness in children. ROP is currently treated with…”
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Hepatoma-derived growth factor-related protein-3 is a novel angiogenic factor by LeBlanc, Michelle E, Wang, Weiwen, Caberoy, Nora B, Chen, Xiuping, Guo, Feiye, Alvarado, Gabriela, Shen, Chen, Wang, Feng, Wang, Hui, Chen, Rui, Liu, Zhao-Jun, Webster, Keith, Li, Wei

“…Hepatoma-derived growth factor-related protein-3 (Hdgfrp3 or HRP-3) was recently reported as a neurotrophic factor and is upregulated in hepatocellular…”
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Dysregulation of club cell biology in idiopathic pulmonary fibrosis by Zuo, Wu-Lin, Rostami, Mahboubeh R, LeBlanc, Michelle, Kaner, Robert J, O'Beirne, Sarah L, Mezey, Jason G, Leopold, Philip L, Quast, Karsten, Visvanathan, Sudha, Fine, Jay S, Thomas, Matthew J, Crystal, Ronald G

“…Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic fibrotic lung disease with an irreversible decline of lung function. "Bronchiolization",…”
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Cell-specific expression of lung disease risk-related genes in the human small airway epithelium by Zuo, Wu-Lin, Rostami, Mahboubeh R, Shenoy, Shushila A, LeBlanc, Michelle G, Salit, Jacqueline, Strulovici-Barel, Yael, O'Beirne, Sarah L, Kaner, Robert J, Leopold, Philip L, Mezey, Jason G, Schymeinsky, Juergen, Quast, Karsten, Visvanathan, Sudha, Fine, Jay S, Thomas, Matthew J, Crystal, Ronald G

“…The human small airway epithelium (SAE) plays a central role in the early events in the pathogenesis of most inherited and acquired lung disorders. Little is…”
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Reticulocalbin-1 facilitates microglial phagocytosis by Ding, Ying, Caberoy, Nora B, Guo, Feiye, LeBlanc, Michelle E, Zhang, Chenming, Wang, Weiwen, Wang, Feng, Chen, Rui, Li, Wei

“…Phagocytosis is critical to the clearance of apoptotic cells, cellular debris and deleterious metabolic products for tissue homeostasis. Phagocytosis ligands…”
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Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes by Kessler, Michael D., Damask, Amy, O’Keeffe, Sean, Banerjee, Nilanjana, Li, Dadong, Watanabe, Kyoko, Marketta, Anthony, Van Meter, Michael, Semrau, Stefan, Horowitz, Julie, Tang, Jing, Kosmicki, Jack A., Rajagopal, Veera M., Zou, Yuxin, Houvras, Yariv, Ghosh, Arkopravo, Gillies, Christopher, Mbatchou, Joelle, White, Ryan R., Verweij, Niek, Bovijn, Jonas, Parikshak, Neelroop N., LeBlanc, Michelle G., Jones, Marcus, Glass, David J., Lotta, Luca A., Cantor, Michael N., Atwal, Gurinder S., Locke, Adam E., Ferreira, Manuel A. R., Deering, Raquel, Paulding, Charles, Shuldiner, Alan R., Thurston, Gavin, Ferrando, Adolfo A., Salerno, Will, Reid, Jeffrey G., Overton, John D., Marchini, Jonathan, Kang, Hyun M., Baras, Aris, Abecasis, Gonçalo R., Jorgenson, Eric

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Use of a low-volume uterine flush for diagnosing endometritis in chronically infertile mares by LeBlanc, Michelle M., Magsig, Joshua, Stromberg, Arnold J.

“…Low-volume uterine flush ( n = 401) was performed in 308 infertile mares to diagnose endometritis. Mares evaluated were either barren after three or more…”
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Prioritizing Solutions and Improving Resources among Young Pediatric Brain Tumor Survivors: Results of an Online Survey by Bonanno, Marco, Bourque, Claude Julie, Robichaud, Lye-Ann, Levesque, Ariane, Lacoste-Julien, Ariane, Rondeau, Émélie, Dubé, Émilie, Leblanc, Michelle, Bertrand, Marie-Claude, Provost, Carole, Desjardins, Leandra, Sultan, Serge

“…Pediatric Brain Tumor Survivors (PBTS) often experience social, academic and employment difficulties during aftercare. Despite their needs, they often do not…”
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Pathogenic role and therapeutic potential of pleiotrophin in mouse models of ocular vascular disease by Wang, Weiwen, LeBlanc, Michelle E., Chen, Xiuping, Chen, Ping, Ji, Yanli, Brewer, Megan, Tian, Hong, Spring, Samantha R., Webster, Keith A., Li, Wei

“…Angiogenic factors play an important role in the pathogenesis of diabetic retinopathy (DR), neovascular age-related macular degeneration (nAMD) and retinopathy…”
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Lyar Is a New Ligand for Retinal Pigment Epithelial Phagocytosis by Guo, Feiye, Ding, Ying, Caberoy, Nora B., Alvarado, Gabriela, Liu, Robert, Shen, Chen, Yu, Jisu, Zhou, Yixiong, Salero, Enrique, LeBlanc, Michelle E., Wang, Weiwen, Li, Wei

“…ABSTRACT Phagocytosis is critical to tissue homeostasis, as highlighted by phagocytosis defect of retinal pigment epithelial (RPE) cells with debris…”
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Elements of the Endomucin Extracellular Domain Essential for VEGF-Induced VEGFR2 Activity by Hu, Zhengping, Cano, Issahy, Saez-Torres, Kahira L, LeBlanc, Michelle E, Saint-Geniez, Magali, Ng, Yin-Shan, Argüeso, Pablo, D'Amore, Patricia A

“…Endomucin (EMCN) is the type I transmembrane glycoprotein, mucin-like component of the endothelial cell glycocalyx. We have previously shown that EMCN is…”
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Smoking shifts human small airway epithelium club cells toward a lesser differentiated population by Rostami, Mahboubeh R., LeBlanc, Michelle G., Strulovici-Barel, Yael, Zuo, Wulin, Mezey, Jason G., O’Beirne, Sarah L., Kaner, Robert J., Leopold, Philip L., Crystal, Ronald G.

“…The club cell, a small airway epithelial (SAE) cell, plays a central role in human lung host defense. We hypothesized that subpopulations of club cells with…”
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