Search Results - "LeBlanc, Amanda J"

Impact of Cell Composition and Geometry on Human Induced Pluripotent Stem Cells-Derived Engineered Cardiac Tissue by Nakane, Takeichiro, Masumoto, Hidetoshi, Tinney, Joseph P., Yuan, Fangping, Kowalski, William J., Ye, Fei, LeBlanc, Amanda J., Sakata, Ryuzo, Yamashita, Jun K., Keller, Bradley B.

“…The current study describes a scalable, porous large-format engineered cardiac tissue (LF-ECT) composed of human induced pluripotent stem cells (hiPSCs)…”
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Adipose-derived cells improve left ventricular diastolic function and increase microvascular perfusion in advanced age by Kelm, Natia Q, Beare, Jason E, Yuan, Fangping, George, Monika, Shofner, Charles M, Keller, Bradley B, Hoying, James B, LeBlanc, Amanda J

“…An early manifestation of coronary artery disease in advanced age is the development of microvascular dysfunction leading to deficits in diastolic function…”
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Adaptation of the Coronary Microcirculation in Aging by LeBlanc, Amanda J., Hoying, James B.

“…Advancing age will affect every individual and its impact on health deserves significant attention particularly as we address therapeutic possibilities to…”
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The heart of physiological reports by Lindsey, Merry L, Brunt, Keith R, Kleinbongard, Petra, Carter, Jason R, Ripplinger, Crystal M, Kassiri, Zamaneh, Hansell Keehan, Kara, LeBlanc, Amanda J, Kirk, Jonathan A

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Microvascular Repair: Post-Angiogenesis Vascular Dynamics by LEBLANC, AMANDA J., KRISHNAN, LAXMINARAYANAN, SULLIVAN, CHRISTOPHER J., WILLIAMS, STUART K., HOYING, JAMES B.

“…Please cite this paper as: LeBlanc AJ, Krishnan L, Sullivan CJ, Williams SK, Hoying JB. Microvascular repair: post‐angiogenesis vascular dynamics…”
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Thrombospondin‐1 mediates Drp‐1 signaling following ischemia reperfusion in the aging heart by Kelm, Natia Q., Beare, Jason E., Weber, Gregory J., LeBlanc, Amanda J.

“…Background Ischemia reperfusion (IR) injury leads to activation of dynamin‐related protein (Drp‐1), causing mitochondrial fission and generation of reactive…”
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Adipose-Derived Stromal Vascular Fraction Cell Effects on a Rodent Model of Thin Endometrium by Hunter, 2nd, Robert K, Nevitt, Chris D, Gaskins, Jeremy T, Keller, Bradley B, Bohler, Jr, Henry C L, LeBlanc, Amanda J

“…Endometrial dysfunction affects approximately 1% of infertile women, and there is currently no standard therapy for improving fertility treatment outcomes in…”
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Estrogen replacement restores flow-induced vasodilation in coronary arterioles of aged and ovariectomized rats by LeBlanc, Amanda J, Reyes, Rafael, Kang, Lori S, Dailey, Robert A, Stallone, John N, Moningka, Natasha C, Muller-Delp, Judy M

“…The risk for cardiovascular disease (CVD) increases with advancing age; however, the age at which CVD risk increases significantly is delayed by more than a…”
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Evolution of the rat hind limb transplant as an experimental model of vascularized composite allotransplantation: Approaches and advantages by Fleissig, Yoram Y, Beare, Jason E, LeBlanc, Amanda J, Kaufman, Christina L

“…As clinical experience with surgical techniques and immunosuppression in vascularized composite allotransplantation recipients has accumulated, vascularized…”
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Systemically Delivered Adipose Stromal Vascular Fraction Cells Disseminate to Peripheral Artery Walls and Reduce Vasomotor Tone Through a CD11b+ Cell‐Dependent Mechanism by Morris, Marvin E., Beare, Jason E., Reed, Robert M., Dale, Jacob R., LeBlanc, Amanda J., Kaufman, Christina L., Zheng, Huaiyu, Ng, Chin K., Williams, Stuart K., Hoying, James B.

“…The hypothesis that autologous stromal vascular fraction (SVF) cells therapeutically modulate peripheral artery vasoactivity in syngeneic mouse models of small…”
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A step closer to improving cardiac homing of adipose-derived mesenchymal stem cells by LeBlanc, Amanda J, Uchida, Shizuka

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Reinforcing rigor and reproducibility expectations for use of sex and gender in cardiovascular research by Lindsey, Merry L, LeBlanc, Amanda J, Ripplinger, Crystal M, Carter, Jason R, Kirk, Jonathan A, Hansell Keehan, Kara, Brunt, Keith R, Kleinbongard, Petra, Kassiri, Zamaneh

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Adipose Stromal Vascular Fraction Reverses Mitochondrial Hyperfission in Coronary Microvessels in Aging by Tracy, Evan P., Nair, Rajeev, Beare, Jason E., LeBlanc, Amanda J.

“…Introduction In aging post‐menopausal women, Coronary Microvascular Disease (CMD) leads to hyperconstricted tone, reduced perfusion and chronic micro‐ischemia…”
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Improving rigor and reproducibility in cardiovascular research by Lindsey, Merry L, LeBlanc, Amanda J, Bertrand, Luc, Bradshaw, Amy D, Kleinbongard, Petra

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Cell therapy-induced recovery of dysfunctional microvasculature by Tracy, Evan Paul, Rowe, Gabrielle, LeBlanc, Amanda J

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Thrombospondin-1, Free Radicals, and the Coronary Microcirculation: The Aging Conundrum by LeBlanc, Amanda J, Kelm, Natia Q

“…Successful matching of cardiac metabolism to perfusion is accomplished primarily through vasodilation of the coronary resistance arterioles, but the mechanism…”
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Sex still matters in cardiovascular research by Lindsey, Merry L, Carter, Jason R, Ripplinger, Crystal M, Kassiri, Zamaneh, Hansell Keehan, Kara, Brunt, Keith R, Kirk, Jonathan A, Kleinbongard, Petra, LeBlanc, Amanda J

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Mimicking Clinical Rejection Patterns in a Rat Osteomyocutaneous Flap Model of Vascularized Composite Allotransplantation by Beare, Jason E., Fleissig, Yoram, Kelm, Natia Q., Reed, Robert M., LeBlanc, Amanda J., Hoying, James B., Kaufman, Christina L.

“…Graft loss in vascularized composite allotransplantation (VCA) is more often associated with vasculopathy and chronic rejection (CR) than acute cellular…”
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Looking backward to plan forward by Lindsey, Merry L, Kirk, Jonathan A, LeBlanc, Amanda J, Brunt, Keith R, Carter, Jason R, Hansell Keehan, Kara, Ripplinger, Crystal M, Kleinbongard, Petra, Kassiri, Zamaneh

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Cell therapy rescues aging-induced beta-1 adrenergic receptor and GRK2 dysfunction in the coronary microcirculation by Rowe, Gabrielle, Tracy, Evan, Beare, Jason E., LeBlanc, Amanda J.

“…Our past study showed that coronary arterioles isolated from adipose-derived stromal vascular fraction (SVF)–treated rats showed amelioration of the…”
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