Search Results - "Le Souëf, Peter N"

Infant lung function predicts asthma persistence and remission in young adults by Owens, Louisa, Laing, Ingrid A., Zhang, Guicheng, Le Souëf, Peter N.

“…ABSTRACT Background and objective Asthma in adults is associated with a persistent reduction in lung function from childhood, but this link has not been…”
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Net benefit of smaller human populations to environmental integrity and individual health and wellbeing by Saraswati, Chitra Maharani, Judge, Melinda A, Weeda, Lewis J Z, Bassat, Quique, Prata, Ndola, Le Souëf, Peter N, Bradshaw, Corey J A

“…The global human population is still growing such that our collective enterprise is driving environmental catastrophe. Despite a decline in average population…”
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T‐cell responses against rhinovirus species A and C in asthmatic and healthy children by Gaido, Cibele M., Granland, Caitlyn, Laing, Ingrid A., Le Souëf, Peter N., Thomas, Wayne R., Currie, Andrew J., Hales, Belinda J.

“…Background Infections by rhinovirus (RV) species A and C are the most common causes of exacerbations of asthma and a major cause of exacerbations of other…”
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CD46 Measles Virus Receptor Polymorphisms Influence Receptor Protein Expression and Primary Measles Vaccine Responses in Naive Australian Children by Clifford, Holly D, Hayden, Catherine M, Khoo, Siew-Kim, Zhang, Guicheng, Le Souëf, Peter N, Richmond, Peter

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The Relationship between Infant Airway Function, Childhood Airway Responsiveness, and Asthma by Turner, Stephen W, Palmer, Lyle J, Rye, Peter J, Gibson, Neil A, Judge, Parveenjeet K, Cox, Moreen, Young, Sally, Goldblatt, Jack, Landau, Louis I, Le Souef, Peter N

“…The relationship between reduced pulmonary function in early life and persistent wheeze (PW) in school-aged children remains uncertain. In this study, VmaxFRC…”
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Age-specific Relationship between CD14 and Atopy in a Cohort Assessed from Age 8 to 25 Years by O'Donnell, Anne R, Toelle, Brett G, Marks, Guy B, Hayden, Catherine M, Laing, Ingrid A, Peat, Jennifer K, Goldblatt, Jack, Le Souef, Peter N

“…CD14 influences postnatal switching of T helper cell responses. CD14 C-159T has been associated with altered CD14 and IgE levels in cross-sectional studies…”
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Reduced infant lung function, active smoking, and wheeze in 18-year-old individuals by Mullane, David, Turner, Steve W, Cox, Des W, Cox, Des, Goldblatt, Jack, Landau, Lou I, le Souëf, Peter N

“…IMPORTANCE This is the first study to link reduced lung function in early life, before the development of symptoms, to wheeze in 18-year-olds. Additionally,…”
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Lower infant mortality, higher household size, and more access to contraception reduce fertility in low- and middle-income nations by Bradshaw, Corey J A, Perry, Claire, Judge, Melinda A, Saraswati, Chitra M, Heyworth, Jane, Le Souëf, Peter N

“…Although average contraceptive use has increased globally in recent decades, an estimated 222 million (26%) of women of child-bearing age worldwide face an…”
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Linking the westernised oropharyngeal microbiome to the immune response in Chinese immigrants by Guo, Jing, Zhang, Xiaoping, Saiganesh, Aarti, Peacock, Christopher, Chen, Shu, Dykes, Gary A, Hales, Belinda J, Le Souëf, Peter N, Zhang, Guicheng

“…Human microbiota plays a fundamental role in modulating the immune response. Western environment and lifestyle are envisaged to alter the human microbiota with…”
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HIV infection in Eastern and Southern Africa: Highest burden, largest challenges, greatest potential by Parker, Erica, Judge, Melinda A, Macete, Eusebio, Nhampossa, Tacilta, Dorward, Jienchi, Langa, Denise C, Schacht, Caroline De, Couto, Aleny, Vaz, Paula, Vitoria, Marco, Molfino, Lucas, Idowu, Rachel T, Bhatt, Nilesh, Naniche, Denise, Le Souëf, Peter N

“…The burden of HIV is especially concerning for Eastern and Southern Africa (ESA), as despite expansion of test-and-treat programmes, this region continues to…”
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Comparison of rhinovirus antibody titers in children with asthma exacerbations and species-specific rhinovirus infection by Iwasaki, Jua, BSc (Hons), Smith, Wendy-Anne, PhD, Khoo, Siew-Kim, BSc (Hons), Bizzintino, Joelene, PhD, Zhang, Guicheng, PhD, Cox, Des W., MD, Laing, Ingrid A., PhD, Le Souëf, Peter N., MD, Thomas, Wayne R., PhD, Hales, Belinda J., PhD

“…Background Asthma exacerbations are associated with human rhinovirus (HRV) infections, and more severe exacerbations are associated with HRV-C. We have…”
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Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children by Cuthbertson, Leah, Oo, Stephen W C, Cox, Michael J, Khoo, Siew-Kim, Cox, Des W, Chidlow, Glenys, Franks, Kimberley, Prastanti, Franciska, Borland, Meredith L, Gern, James E, Smith, David W, Bizzintino, Joelene A, Laing, Ingrid A, Le Souëf, Peter N, Moffatt, Miriam F, Cookson, William O C

“…Acute viral wheeze in children is a major cause of hospitalisation and a major risk factor for the development of asthma. However, the role of the respiratory…”
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IgE and IgG anti–house dust mite specificities in allergic disease by Hales, Belinda J., Martin, Andrew C., Pearce, Leigh J., Laing, Ingrid A., Hayden, Catherine M., Goldblatt, Jack, Le Souëf, Peter N., Thomas, Wayne R.

“…There are few studies that quantitatively compare IgE and IgG antibody binding to the major and minor house dust mite allergens. To measure the IgE and IgG…”
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Prevalence of allergic sensitization, hay fever, eczema, and asthma in a longitudinal birth cohort by Owens, Louisa, Laing, Ingrid A, Zhang, Guicheng, Turner, Stephen, Le Souëf, Peter N

“…The aim of this study was to longitudinally assess the prevalence of allergic sensitization, asthma, eczema and hay fever from infancy to adulthood in a single…”
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Rhinovirus species and clinical features in children hospitalised with pneumonia from Mozambique by Annamalay, Alicia A., Lanaspa, Miguel, Khoo, Siew‐Kim, Madrid, Lola, Acácio, Sozinho, Zhang, Guicheng, Laing, Ingrid A., Gern, James, Goldblatt, Jack, Bizzintino, Joelene, Lehmann, Deborah, Le Souëf, Peter N., Bassat, Quique

“…Objectives To describe the prevalence of human rhinovirus (RV) species in children hospitalised with pneumonia in Manhiça, Mozambique, and the associations…”
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Lung function trajectories from pre-school age to adulthood and their associations with early life factors: a retrospective analysis of three population-based birth cohort studies by Belgrave, Danielle C M, Granell, Raquel, Turner, Steve W, Curtin, John A, Buchan, Iain E, Le Souëf, Peter N, Simpson, Angela, Henderson, A John, Custovic, Adnan

“…Maximal lung function in early adulthood is an important determinant of mortality and COPD. We investigated whether distinct trajectories of lung function are…”
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Measuring exhaled nitric oxide levels in adults: the importance of atopy and airway responsiveness by Franklin, Peter J, Stick, Stephen M, Le Souëf, Peter N, Ayres, Jon G, Turner, Stephen W

“…Raised exhaled nitric oxide (Feno) levels have been associated with asthma. However, we have found that in children, Feno was increased in atopic children with…”
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Western environment/lifestyle is associated with increased genome methylation and decreased gene expression in Chinese immigrants living in Australia by Zhang, Guicheng, Wang, Kui, Schultz, Ennee, Khoo, Siew-Kim, Zhang, Xiaopeng, Annamalay, Alicia, Laing, Ingrid A., Hales, Belinda J., Goldblatt, Jack, Le Souëf, Peter N.

“…Introduction: Several human diseases and conditions are disproportionally distributed in the world with a significant “Western‐developed” vs…”
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Impaired interferon response in plasmacytoid dendritic cells from children with persistent wheeze by Coenen, Isabelle, de Jong, Emma, Jones, Anya C., Khoo, Siew-Kim, Foo, Shihui, Howland, Shanshan Wu, Ginhoux, Florent, Le Souëf, Peter N., Holt, Patrick G., Strickland, Deborah H., Laing, Ingrid A., Leffler, Jonatan

“…[Display omitted] Impaired interferon response and allergic sensitization may contribute to virus-induced wheeze and asthma development in young children…”
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SLAM and DC-SIGN measles receptor polymorphisms and their impact on antibody and cytokine responses to measles vaccine by Clifford, Holly D, Richmond, Peter, Khoo, Siew-Kim, Zhang, Guicheng, Yerkovich, Stephanie T, Le Souëf, Peter N, Hayden, Catherine M

“…Abstract Background Despite the use of measles vaccine, measles virus continues to circulate and cause severe disease. Immune responses to the measles vaccine…”
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