Search Results - "Le Mentec, Hélène"
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Genome-Wide Transcriptional and Functional Analysis of Human T Lymphocytes Treated with Benzo[ α ]pyrene
Published in International journal of molecular sciences (17-11-2018)“…Polycyclic aromatic hydrocarbons (PAHs) are widely distributed environmental contaminants, known to affect T lymphocytes. However, the molecular targets and…”
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A New In Vivo Zebrafish Bioassay Evaluating Liver Steatosis Identifies DDE as a Steatogenic Endocrine Disruptor, Partly through SCD1 Regulation
Published in International journal of molecular sciences (15-02-2023)“…Non-alcoholic fatty liver disease (NAFLD), which starts with liver steatosis, is a growing worldwide epidemic responsible for chronic liver diseases. Among its…”
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Differential influences of the BPA, BPS and BPF on in vitro IL-17 secretion by mouse and human T cells
Published in Toxicology in vitro (01-12-2020)“…The endocrine disruptor and food contaminant bisphenol A (BPA) is frequently present in consumer plastics and can produce several adverse health effects…”
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Induction of drug metabolizing enzyme and drug transporter expression by antifungal triazole pesticides in human HepaSH hepatocytes
Published in Chemosphere (Oxford) (01-10-2024)“…Triazole pesticides are widely used fungicides, to which humans are rather highly exposed. They are known to activate drug-sensing receptors regulating…”
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Transcriptomic analysis in zebrafish larvae identifies iron-dependent mitochondrial dysfunction as a possible key event of NAFLD progression induced by benzo[a]pyrene/ethanol co-exposure
Published in Cell biology and toxicology (01-04-2023)“…Non-alcoholic fatty liver disease (NAFLD) is a worldwide epidemic for which environmental contaminants are increasingly recognized as important etiological…”
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Combinatorial pathway disruption is a powerful approach to delineate metabolic impacts of endocrine disruptors
Published in FEBS letters (01-12-2022)“…The prevalence of metabolic diseases, such as obesity, diabetes, metabolic syndrome and chronic liver diseases among others, has been rising for several years…”
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Corrigendum to “Obesity III: Obesogen assays: Limitations, strengths, and new directions” [Biochem. Pharmacol. 199 (2022) 115014]
Published in Biochemical pharmacology (01-08-2022)Get full text
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Combinatorial pathway disruption is a powerful approach to delineate metabolic impacts of endocrine disruptors
Published in FEBS letters (22-08-2022)“…The prevalence of metabolic diseases, such as obesity, diabetes, metabolic syndrome and chronic liver diseases among others, has been rising for several years…”
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Obesity II: Establishing causal links between chemical exposures and obesity
Published in Biochemical pharmacology (01-05-2022)“…Reducing exposure to obesogens is a strategy for preventing obesity. [Display omitted] •There is an expanding global obesity pandemic.•Ubiquitous environmental…”
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Obesity III: Obesogen assays: Limitations, strengths, and new directions
Published in Biochemical pharmacology (01-05-2022)“…[Display omitted] •There are increasing novel capabilities to identify and assess obesogens.•There is still a reliance on using well-defined models with…”
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Obesity III: Obesogen assays: Limitations, strengths, and new directions
Published in Biochemical pharmacology (01-05-2022)“…There is increasing evidence of a role for environmental contaminants in disrupting metabolic health in both humans and animals. Despite a growing need for…”
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Obesity II: Establishing causal links between chemical exposures and obesity
Published in Biochemical pharmacology (01-05-2022)“…Obesity is a multifactorial disease with both genetic and environmental components. The prevailing view is that obesity results from an imbalance between…”
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Obesity II: Establishing causal links between chemical exposures and obesity (vol 199, 115015, 2022)
Published in BIOCHEMICAL PHARMACOLOGY (2022)Get full text
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Corrigendum to “Obesity II: Establishing causal links between chemical exposures and obesity” [Biochem. Pharmacol. 199 (2022) 115015]
Published in Biochemical pharmacology (01-08-2022)Get full text
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