Search Results - "Le Loarer, F."

Homogeneous myxoid liposarcomas mimicking cysts on MRI: A challenging diagnosis by Crombé, A., Loarer, F. Le, Alberti, N., Buy, X., Stoeckle, E., Cousin, S., Toulmonde, M., Coindre, J.M., Italiano, A., Kind, M.

“…Myxoid liposarcoma (M-LPS) is the second most frequent subtype of liposarcoma. Foci of fat on MRI are strongly suggestive of this diagnosis. The aims of this…”
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The risk of postoperative complications and functional impairment after multimodality treatment for limb and trunk wall soft-tissue sarcoma: long term results from a monocentric series by Stoeckle, Eberhard, Dr, Michot, Audrey, MD, Regal, Leslie, MSc, Babre, Florence, MD, Sargos, Paul, MD, Henriques de Figueiredo, Bénédicte, MD, Brouste, Véronique, MSc, Italiano, Antoine, MD, PhD, Toulmonde, Maud, MD, Le Loarer, François, MD, PhD, Kind, Michèle, MD

“…Abstract Background and objectives Conservative surgery for soft-tissue sarcoma (STS) within multimodality treatment attempts to reconcile two contradictory…”
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Pembrolizumab in soft-tissue sarcomas with tertiary lymphoid structures: a phase 2 PEMBROSARC trial cohort by Italiano, A., Bessede, A., Pulido, M., Bompas, E., Piperno-Neumann, S., Chevreau, C., Penel, N., Bertucci, F., Toulmonde, M., Bellera, C., Guegan, J. P., Rey, C., Sautès-Fridman, C., Bougoüin, A., Cantarel, C., Kind, M., Spalato, M., Dadone-Montaudie, B., Le Loarer, F., Blay, J. Y., Fridman, W. H.

“…Immune checkpoint inhibitors (ICIs) show limited clinical activity in patients with advanced soft-tissue sarcomas (STSs). Retrospective analysis suggests that…”
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Programmed cell death 1 (PD-1) targeting in patients with advanced osteosarcomas: results from the PEMBROSARC study by Le Cesne, A., Marec-Berard, P., Blay, J.-Y., Gaspar, N., Bertucci, F., Penel, N., Bompas, E., Cousin, S., Toulmonde, M., Bessede, A., Fridman, W.H., Sautes-Fridman, C., Kind, M., Le Loarer, F., Pulido, M., Italiano, A.

“…There are some lines of evidence suggesting a potential role of immunotherapy for treating patients with osteosarcomas. This was an open-label, multicentre,…”
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Mature tertiary lymphoid structure is a specific biomarker of cancer immunotherapy and does not predict outcome to chemotherapy in non-small-cell lung cancer by Brunet, M., Crombé, A., Cousin, S., Vanhersecke, L., Le Loarer, F., Bessede, A., Italiano, A.

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Plasma proteomics identifies leukemia inhibitory factor (LIF) as a novel predictive biomarker of immune-checkpoint blockade resistance by Loriot, Y., Marabelle, A., Guégan, J.P., Danlos, F.X., Besse, B., Chaput, N., Massard, C., Planchard, D., Robert, C., Even, C., Khettab, M., Tselikas, L., Friboulet, L., André, F., Nafia, I., Le Loarer, F., Soria, J.C., Bessede, A., Italiano, A.

“…Immune checkpoint blockers (ICBs) are now widely used in oncology. Most patients, however, do not derive benefit from these agents. Therefore, there is a…”
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Circulating L-arginine predicts the survival of cancer patients treated with immune checkpoint inhibitors by Peyraud, F., Guégan, J.-P., Bodet, D., Nafia, I., Fontan, L., Auzanneau, C., Cousin, S., Roubaud, G., Cabart, M., Chomy, F., Le Loarer, F., Chaput, N., Danlos, F.-X., Planchard, D., Even, C., Khettab, M., Tselikas, L., Besse, B., Barlesi, F., Soria, J.-C., Marabelle, A., Bessede, A., Italiano, A.

“…The discovery of immune checkpoint inhibitors (ICIs) has revolutionized the systemic approach to cancer treatment. Most patients receiving ICIs, however, do…”
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Epithelioid hemangio-endothelioma (EHE) in NETSARC: The nationwide series of 267 patients over 12 years by Blay, JY, Piperno-Neumann, S., Watson, S., Dufresne, A., Valentin, T., Duffaud, F., Toulmonde, M., Italiano, A., Bertucci, F., Tlemsani, C., Firmin, N., Bompas, E., Perrin, C., Ropars, M., Saada-Bouzid, E., Dubray-Longeras, P., Hervieu, A., Lebbe, C., Gantzer, J., Chaigneau, L., Fiorenza, F., Rios, M., Isambert, N., Soibinet, P., Boudou-Roquette, P., Verret, B., Ferron, G., Ryckewaert, T., Lebellec, L., Brahmi, M., Gouin, F., Meeus, P., Vaz, G., Le Loarer, F., Karanian, M., De Pinieux, G., Ducimetiere, F., Chemin, C., Morelle, M., Le Cesne, A., Penel, N.

“…Epithelioid hemangioendothelioma (EHE) is an ultrarare sarcoma whose natural history and treatment is not well defined. We report on the presentation and…”
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Sclerosing Epithelioid Fibrosarcoma (SEF) versus Low Grade Fibromyxoid Sarcoma (LGFMS): Presentation and outcome in the nationwide NETSARC+ series of 330 patients over 13 years by Blay, J Y, Tlemsani, C, Toulmonde, M, Italiano, A, Rios, M, Bompas, E, Valentin, T, Duffaud, F, Le Nail, L R, Watson, S, Firmin, N, Dubray-Longeras, P, Ropars, M, Perrin, C, Hervieu, A, Lebbe, C, Saada-Bouzid, E, Soibinet, P, Fiorenza, F, Bertucci, F, Boudou, P, Vaz, G, Bonvalot, S, Honoré, C, Marec-Berard, P, Minard, V, Cleirec, M, Biau, D, Meeus, P, Babinet, A, Dumaine, V, Carriere, S, Fau, M, Decanter, G, Gouin, F, Ngo, C, Le Loarer, F, Karanian, M, Meurgey, A, Dufresne, A, Brahmi, M, Chemin-Airiau, C, Ducimetiere, F, Penel, N, Le Cesne, A

“…Sclerosing Epithelioid Fibrosarcoma (SEF) and Low Grade Fibromyxoid Sarcoma (LGFMS) are ultrarare sarcomas sharing common translocations whose natural history…”
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CHK1 inhibition in soft-tissue sarcomas: biological and clinical implications by Laroche-Clary, A., Lucchesi, C., Rey, C., Verbeke, S., Bourdon, A., Chaire, V., Algéo, M.-P., Cousin, S., Toulmonde, M., Vélasco, V., Shutzman, J., Savina, A., Le Loarer, F., Italiano, A.

“…Inhibition of ChK1 appears as a promising strategy for selectively potentiate the efficacy of chemotherapeutic agents in G1 checkpoint-defective tumor cells…”
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Pre- or postoperative radiotherapy for soft tissue sarcomas by Llacer-Moscardo, C., Terlizzi, M., Bonvalot, S., Le Loarer, F., Carrère, S., Tetrau, R., D’ascoli, A., Lerouge, D., Le Péchoux, C., Thariat, J.

“…Sarcomas are rare tumours arising from mesenchymal tissue. A multimodal management in an expert centre combining surgery and radiotherapy is the current…”
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Expression and prognostic significance of PDGF ligands and receptors across soft tissue sarcomas by Brahmi, M., Lesluyes, T., Dufresne, A., Toulmonde, M., Italiano, A., Mir, O., Le Cesne, A., Valentin, T., Chevreau, C., Bonvalot, S., Penel, N., Coindre, J.-M., Le Guellec, S., Le Loarer, F., Karanian, M., Blay, J.-Y., Chibon, F.

“…While the anti-PDGFRA antibody olaratumab failed to confirm an impact on survival in unselected advanced soft tissue sarcoma (STS) patients, the level of…”
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Surgery in reference centers improves survival of sarcoma patients: a nationwide study by Blay, J.-Y., Honoré, C., Stoeckle, E., Meeus, P., Jafari, M., Gouin, F., Anract, P., Ferron, G., Rochwerger, A., Ropars, M., Carrere, S., Marchal, F., Sirveaux, F., Di Marco, A., Le Nail, L.R., Guiramand, J., Vaz, G., Machiavello, J.-C., Marco, O., Causeret, S., Gimbergues, P., Fiorenza, F., Chaigneau, L., Guillemin, F., Guilloit, J.-M., Dujardin, F., Spano, J.-P., Ruzic, J.-C., Michot, A., Soibinet, P., Bompas, E., Chevreau, C., Duffaud, F., Rios, M., Perrin, C., Firmin, N., Bertucci, F., Le Pechoux, C., Le Loarer, F., Collard, O., Karanian-Philippe, M., Brahmi, M., Dufresne, A., Dupré, A., Ducimetière, F., Giraud, A., Pérol, D., Toulmonde, M., Ray-Coquard, I., Italiano, A., Le Cesne, A., Penel, N., Bonvalot, S.

“…NETSARC (netsarc.org) is a network of 26 sarcoma reference centers with specialized multidisciplinary tumor boards (MDTB) aiming to improve the outcome of…”
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1525TiP TORNADO: A randomized multicenter open-label phase II study evaluating retifanlimab in combination with neoadjuvant chemotherapy in patients with selected retroperitoneal sarcomas by Albert, S., Italiano, A., Toulmonde, M., Cousin, S., Bahleda, R., Brahmi, M., Watson, S., Auzanneau, C., Douiri, N., Poignie, L., Lortal, B., Le Loarer, F., Bellera, C.

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1921MO Patterns of care, outcome and molecular landscape of PATZ1-rearranged sarcomas identifies two prognostic profiles: A cohort study from the French Sarcoma Group (FSG) by Vanacker, H., Le Loarer, F., Karanian, M., Meurgey, A., Dufresne, A., El Zein, S., Blay, J-Y., Collard, O., Ray-Coquard, I.L., Waissi, W.A., Pissaloux, D., Paindavoine, S., Houlier, A., Pierron, G., Meeus, P., Tirode, F., Brahmi, M.

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1955P Distinguishing lipomas from atypical lipomatous tumors/well differentiated liposarcomas in histology slides using deep learning by Karanian, M., Camara, A., Klein, J., Marchand, T., Maussion, C., Rousseau, V., Bonnotte, T., Perret, R., Le Loarer, F., Ngo, C., Korbi, S., Mansour, Y., Meurgey, A., Jean-Denis, M., Italiano, A., Blay, J-Y., Coindre, J.M.

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Severe drug eruption caused by a medication error by Le Loarer, F, Carré-Gislard, D, Baricault, S, Bravard, P

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1527TiP CONGRATS-combination of nivolumab plus relatlimab in patients with advanced or metastatic soft-tissue sarcoma: A proof-of-concept randomized phase II study by Spalato Ceruso, M., Albert, S., Italiano, A., Toulmonde, M., Cousin, S., Grellety, T., Blay, J-Y., Verret, B., Auzanneau, C., Valade, V., Poignie, L., Lortal, B., Kind, M., Le Loarer, F., Pulido, M.

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1484O Deep learning predicts patients’ outcome and mutations from H&E slides in gastrointestinal stromal tumor (GIST) by Italiano, A., Fu, Y., Karanian, M., Perret, R., Camara, A., Le Loarer, F., Jean-Denis, M., Hostein, I., Michot, A., Ducimetiere, F., Giraud, A., Courreges, J-B., Courtet, K., Laizet, Y., du Terrail, J.O., Schmauch, B., Maussion, C., Blay, J-Y., Coindre, J.M.

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1316O Improved nationwide survival of sarcoma patients 10 years after establishment of the NETSARC+ reference center network by Blay, J-Y., Italiano, A., Penel, N., Bompas, E., Duffaud, F., Chevreau, C.M., Anract, P., Perrin, C., Firmin, N., Toulmonde, M., Piperno-Neumann, S., Watson, S., Rios, M., Kurtz, J.E., Bertucci, F., Le Loarer, F., Chemin, C., Morelle, M., Gouin, F., Le Cesne, A.

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