Search Results - "Le Goux, Nelig"
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Calcium Increase and Substance P Release Induced by the Neurotoxin Brevetoxin-1 in Sensory Neurons: Involvement of PAR2 Activation through Both Cathepsin S and Canonical Signaling
Published in Cells (Basel, Switzerland) (17-12-2020)“…Red tides involving expose humans to brevetoxins (PbTxs). Oral exposition triggers neurotoxic shellfish poisoning, whereas inhalation induces a respiratory…”
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Calcium Signaling: From Normal B Cell Development to Tolerance Breakdown and Autoimmunity
Published in Clinical reviews in allergy & immunology (01-10-2017)“…Maintenance of self-tolerance of auto-reactive lymphocytes is a fundamental mechanism to prevent the onset of autoimmune diseases. Deciphering the mechanisms…”
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Identification of 8-Hydroxyquinoline Derivatives That Decrease Cystathionine Beta Synthase (CBS) Activity
Published in International journal of molecular sciences (17-06-2022)“…CBS encodes a pyridoxal 5′-phosphate-dependent enzyme that catalyses the condensation of homocysteine and serine to form cystathionine. Due to its implication…”
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Pacific-Ciguatoxin-2 and Brevetoxin-1 Induce the Sensitization of Sensory Receptors Mediating Pain and Pruritus in Sensory Neurons
Published in Marine drugs (06-07-2021)“…Ciguatera fish poisoning (CFP) and neurotoxic shellfish poisoning syndromes are induced by the consumption of seafood contaminated by ciguatoxins and…”
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STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia
Published in Journal for immunotherapy of cancer (23-04-2019)“…Dysregulation in calcium (Ca ) signaling is a hallmark of chronic lymphocytic leukemia (CLL). While the role of the B cell receptor (BCR) Ca pathway has been…”
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In Vitro Differentiation of Human Skin-Derived Cells into Functional Sensory Neurons-Like
Published in Cells (Basel, Switzerland) (17-04-2020)“…Skin-derived precursor cells (SKPs) are neural crest stem cells that persist in certain adult tissues, particularly in the skin. They can generate a large type…”
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Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research
Published in Reviews of Physiology Biochemistry and Pharmacology (2022)“…The intracellular Ca2+ concentration is mainly controlled by Ca2+ channels. These channels form complexes with K+ channels, which function to amplify Ca2+…”
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