Search Results - "Le Gouill, S."

BH3 profiling identifies heterogeneous dependency on Bcl-2 family members in multiple myeloma and predicts sensitivity to BH3 mimetics by Touzeau, C, Ryan, J, Guerriero, J, Moreau, P, Chonghaile, T N, Le Gouill, S, Richardson, P, Anderson, K, Amiot, M, Letai, A

Get full text

The EBMT/EMCL consensus project on the role of autologous and allogeneic stem cell transplantation in mantle cell lymphoma by Robinson, S, Dreger, P, Caballero, D, Corradini, P, Geisler, C, Ghielmini, M, Le Gouill, S, Kimby, E, Rule, S, Vitolo, U, Dreyling, M, Hermine, O

“…The role of both autologous (autoSCT) and allogeneic stem cell transplantation (alloSCT) in the management of mantle cell lymphoma (MCL) remains to be…”
Get full text

Newly diagnosed and relapsed mantle cell lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up by Dreyling, M, Geisler, C, Hermine, O, Kluin-Nelemans, H C, Le Gouill, S, Rule, S, Shpilberg, O, Walewski, J, Ladetto, M

Get full text

High level of soluble programmed cell death ligand 1 in blood impacts overall survival in aggressive diffuse large B-Cell lymphoma: results from a French multicenter clinical trial by Rossille, D, Gressier, M, Damotte, D, Maucort-Boulch, D, Pangault, C, Semana, G, Le Gouill, S, Haioun, C, Tarte, K, Lamy, T, Milpied, N, Fest, T

“…The dosage of soluble programmed cell death ligand 1 (sPD-L1) protein in the blood of adults with cancer has never been performed in a prospective patient…”
Get full text

French early nationwide idecabtagene vicleucel chimeric antigen receptor T‐cell therapy experience in patients with relapsed/refractory multiple myeloma (FENIX): A real‐world IFM study from the DESCAR‐T registry by Ferment, B., Lambert, J., Caillot, D., Lafon, I., Karlin, L., Lazareth, A., Touzeau, C., Leleu, X., Moya, N., Harel, S., Perrot, A., Bories, P., Vincent, L., Lamure, S., Mohty, M., Malard, F., Manier, S., Yakoub‐Agha, I., Schiano De Colella, J.‐M., Brisou, G., Talbot, A., Decaux, O., Houot, R., Le Gouill, S., Bigot, N., Facon, T., Corre, J., Moreau, P., Arnulf, B.

“…Summary Idecabtagene vicleucel (ide‐cel), a chimeric antigen receptor T‐cell therapy targeting B‐cell maturation antigen (BCMA), received early access program…”
Get full text

Clinical characteristics and prognostic factors of plasmablastic lymphoma patients: analysis of 135 patients from the LYSA group by Tchernonog, E., Faurie, P., Coppo, P., Monjanel, H., Bonnet, A., Algarte Génin, M., Mercier, M., Dupuis, J., Bijou, F., Herbaux, C., Delmer, A., Fabiani, B., Besson, C., Le Gouill, S., Gyan, E., Laurent, C., Ghesquieres, H., Cartron, G.

“…Plasmablastic lymphoma (PBL), initially described in 1997 in the oral cavity of HIV positive patients, is now recognized as a distinct aggressive and rare…”
Get full text

Azacitidine salvage therapy for relapse of myeloid malignancies following allogeneic hematopoietic SCT by Tessoulin, B, Delaunay, J, Chevallier, P, Loirat, M, Ayari, S, Peterlin, P, Le Gouill, S, Gastinne, T, Moreau, P, Mohty, M, Guillaume, T

“…Patients with hematopoietic malignancies relapsing after allogeneic hematopoietic SCT (allo-HSCT) have a poor prognosis. We retrospectively analyzed the…”
Get full text

Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival by WUILLEME-TOUMI, S, ROBILLARD, N, GOMEZ, P, MOREAU, P, LE GOUILL, S, AVET-LOISEAU, H, HAROUSSEAU, J.-L, AMIOT, M, BATAILLE, R

“…We and others have shown that Mcl-1 was essential for the survival of human myeloma cells in vitro. Furthermore, this antiapoptotic protein is upregulated by…”
Get full text

The outcome of reduced intensity allogeneic stem cell transplantation and autologous stem cell transplantation when performed as a first transplant strategy in relapsed follicular lymphoma: an analysis from the Lymphoma Working Party of the EBMT by Robinson, S P, Canals, C, Luang, J J, Tilly, H, Crawley, C, Cahn, J Y, Pohlreich, D, Le Gouill, S, Gilleece, M, Milpied, N, Attal, M, Biron, P, Maury, S, Rambaldi, A, Maertens, J, Capria, S, Colombat, P, Montoto, S, Sureda, A

“…Both auto-SCT and reduced intensity allo-SCT (RIST) are employed in the treatment of relapsed follicular lymphoma (FL). We have analysed the outcome of these…”
Get full text

Allogeneic stem cell transplantation for patients with mantle cell lymphoma who failed autologous stem cell transplantation: a national survey of the SFGM-TC by Tessoulin, B, Ceballos, P, Chevallier, P, Blaise, D, Tournilhac, O, Gauthier, J, Maillard, N, Tabrizi, R, Choquet, S, Carras, S, Ifrah, N, Guillerm, G, Mohty, M, Tilly, H, Socie, G, Cornillon, J, Hermine, O, Daguindau, É, Bachy, E, Girault, S, Marchand, T, Oberic, L, Reman, O, Leux, C, Le Gouill, S

“…Poly-chemotherapy plus rituximab followed by autologous stem cell transplantation (auto-SCT) is standard care for untreated young patients with mantle cell…”
Get full text

The cap-translation inhibitor 4EGI-1 induces apoptosis in multiple myeloma through Noxa induction by Descamps, G, Gomez-Bougie, P, Tamburini, J, Green, A, Bouscary, D, Maïga, S, Moreau, P, Le Gouill, S, Pellat-Deceunynck, C, Amiot, M

“…Background: Cancer cells are frequently addicted to deregulated oncogenic protein translation. The small molecule 4EG-I selectively inhibits the cap-dependent…”
Get full text

Features of Epstein-Barr Virus (EBV) reactivation after reduced intensity conditioning allogeneic hematopoietic stem cell transplantation by Peric, Z, Cahu, X, Chevallier, P, Brissot, E, Malard, F, Guillaume, T, Delaunay, J, Ayari, S, Dubruille, V, Le Gouill, S, Mahe, B, Gastinne, T, Blin, N, Saulquin, B, Harousseau, J-L, Moreau, P, Milpied, N, Coste-Burel, M, Imbert-Marcille, B-M, Mohty, M

“…This single centre study assessed the incidence, kinetics and predictive factors of Epstein-Barr Virus (EBV) reactivation and EBV-related lymphoproliferative…”
Get full text

Effect of graft source on mismatched unrelated donor hemopoietic stem cell transplantation after reduced intensity conditioning by Malard, F, Fürst, S, Loirat, M, Chevallier, P, El-Cheikh, J, Guillaume, T, Delaunay, J, Le Gouill, S, Moreau, P, Blaise, D, Mohty, M

“…This retrospective report compared the results of graft source on outcome after allogeneic stem cell transplantation (allo-SCT) in patients with hematologic…”
Get full text

Safety and efficacy of rituximab in steroid-refractory chronic GVHD by Clavert, A, Chevallier, P, Guillaume, T, Delaunay, J, Le Gouill, S, Mahe, B, Dubruille, V, Gastinne, T, Blin, N, Moreau, P, Mohty, M

Get full text

Impact of lenalidomide on immune functions in the setting of maintenance therapy for multiple myeloma by Brissot, E, Clavert, A, Blin, N, Roland, V, Guillaume, T, Dubruille, V, Mahe, B, Gastinne, T, Le Gouill, S, Gaugler, B, Moreau, P, Mohty, M

Get full text

Second-degree relative donors for T-replete haploidentical allogeneic stem cell transplantation with high-dose post-transplant cyclophosphamide: toward crossing the major HLA barrier by Garnier, A, Guillaume, T, Peterlin, P, Béné, M C, Le Bris, Y, Dubruille, V, Mahé, B, Gastinne, T, Touzeau, C, Blin, N, Le Gouill, S, Moreau, P, Chevallier, P

Get full text

Radioimmunotherapy-augmented BEAM chemotherapy vs BEAM alone as the high-dose regimen for autologous stem cell transplantation (ASCT) in relapsed follicular lymphoma (FL): a retrospective study of the EBMT Lymphoma Working Party by Bento, L, Boumendil, A, Finel, H, Le Gouill, S, Amorim, S, Monjanel, H, Bouabdallah, R, Bay, J O, Nicolas-Virelizier, E, McQuaker, G, Rossi, G, Johnson, R, Huynh, A, Ceballos, P, Rambaldi, A, Bachy, E, Malladi, R, Orchard, K, Pohlreich, D, Tilly, H, Bonifazi, F, Poiré, X, Guilhot, F, Haenel, A, Crawley, C, Metzner, B, Gribben, J, Russell, N H, Damaj, G, Thomson, K, Dreger, P, Montoto, S

“…Relapse remains the most common cause of treatment failure in patients receiving autologous stem cell transplantation (ASCT) for follicular lymphoma (FL). The…”
Get full text

Mast cells in Waldenstrom's macroglobulinemia support lymphoplasmacytic cell growth through CD154/CD40 signaling by Tournilhac, O., Santos, D. D., Xu, L., Kutok, J., Tai, Y.-T., Le Gouill, S., Catley, L., Hunter, Z., Branagan, A. R., Boyce, J. A., Munshi, N., Anderson, K. C., Treon, S. P.

“…Bone marrow (BM) mast cells (MC) are commonly found in association with lymphoplasmacytic cells (LPC) in patients with Waldenström's macroglobulinemia (WM)…”
Get full text

Combination of rituximab, bortezomib, doxorubicin, dexamethasone and chlorambucil (RiPAD+C) as first-line therapy for elderly mantle cell lymphoma patients: results of a phase II trial from the GOELAMS by Houot, R., Le Gouill, S., Ojeda Uribe, M., Mounier, C., Courby, S., Dartigeas, C., Bouabdallah, K., Alexis Vigier, M., Moles, M.P., Tournilhac, O., Arakelyan, N., Rodon, P., El Yamani, A., Sutton, L., Fornecker, L., Assouline, D., Harousseau, J.L., Maisonneuve, H., Caulet-Maugendre, S., Gressin, R.

“…There is no consensual first-line chemotherapy for elderly patients with mantle cell lymphoma (MCL). The GOELAMS (Groupe Ouest-Est des Leucémies Aiguës et…”
Get full text

Escalated lymphodepletion followed by donor lymphocyte infusion can induce a graft-versus-host response without overwhelming toxicity by Guillaume, T, Gaugler, B, Chevallier, P, Delaunay, J, Ayari, S, Clavert, A, Rialland, F, Le Gouill, S, Blin, N, Gastinne, T, Mahé, B, Dubruille, V, Moreau, P, Mohty, M

“…Treatment of relapse of hematological malignancies following allogeneic hematopoietic SCT (allo-HSCT) remains very challenging and relies usually on the…”
Get full text