Search Results - "Le Goffic, Ronan"

Broad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism by Cagno, Valeria, Andreozzi, Patrizia, D’Alicarnasso, Marco, Jacob Silva, Paulo, Mueller, Marie, Galloux, Marie, Le Goffic, Ronan, Jones, Samuel T., Vallino, Marta, Hodek, Jan, Weber, Jan, Sen, Soumyo, Janeček, Emma-Rose, Bekdemir, Ahmet, Sanavio, Barbara, Martinelli, Chiara, Donalisio, Manuela, Rameix Welti, Marie-Anne, Eleouet, Jean-Francois, Han, Yanxiao, Kaiser, Laurent, Vukovic, Lela, Tapparel, Caroline, Král, Petr, Krol, Silke, Lembo, David, Stellacci, Francesco

“…Viral infections kill millions yearly. Available antiviral drugs are virus-specific and active against a limited panel of human pathogens. There are…”
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Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia by Le Goffic, Ronan, Balloy, Viviane, Lagranderie, Micheline, Alexopoulou, Lena, Escriou, Nicolas, Flavell, Richard, Chignard, Michel, Si-Tahar, Mustapha

“…Influenza A virus (IAV) is the etiological agent of a highly contagious acute respiratory disease that causes epidemics and considerable mortality annually…”
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The Influenza Virus Protein PB1-F2 Increases Viral Pathogenesis through Neutrophil Recruitment and NK Cells Inhibition by Vidy, Aurore, Maisonnasse, Pauline, Da Costa, Bruno, Delmas, Bernard, Chevalier, Christophe, Le Goffic, Ronan

“…The influenza A virus (IAV) PB1-F2 protein is a virulence factor contributing to the pathogenesis observed during IAV infections in mammals. In this study,…”
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Identification of One Novel Candidate Probiotic Lactobacillus plantarum Strain Active against Influenza Virus Infection in Mice by a Large-Scale Screening by KECHAOU, Noura, CHAIN, Florian, LANGELLA, Philippe, BERMUDEZ-HUMARAN, Luis G, GRATADOUX, Jean-Jacques, BLUGEON, Sébastien, BERTHO, Nicolas, CHEVALIER, Christophe, LE GOFFIC, Ronan, COURAU, Stephanie, MOLIMARD, Pascal, MARC CHATEL, Jean

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A Short Double-Stapled Peptide Inhibits Respiratory Syncytial Virus Entry and Spreading by Gaillard, Vanessa, Galloux, Marie, Garcin, Dominique, Eléouët, Jean-François, Le Goffic, Ronan, Larcher, Thibaut, Rameix-Welti, Marie-Anne, Boukadiri, Abdelhak, Héritier, Julien, Segura, Jean-Manuel, Baechler, Elodie, Arrell, Miriam, Mottet-Osman, Geneviève, Nyanguile, Origène

“…Synthetic peptides derived from the heptad repeat (HR) of fusion (F) proteins can be used as dominant negative inhibitors to inhibit the fusion mechanism of…”
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Transcriptomic profiling of a chicken lung epithelial cell line (CLEC213) reveals a mitochondrial respiratory chain activity boost during influenza virus infection by Meyer, Léa, Leymarie, Olivier, Chevalier, Christophe, Esnault, Evelyne, Moroldo, Marco, Da Costa, Bruno, Georgeault, Sonia, Roingeard, Philippe, Delmas, Bernard, Quéré, Pascale, Le Goffic, Ronan

“…Avian Influenza virus (AIV) is a major concern for the global poultry industry. Since 2012, several countries have reported AIV outbreaks among domestic…”
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Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein by Le Goffic, Ronan, Leymarie, Olivier, Chevalier, Christophe, Rebours, Emmanuelle, Da Costa, Bruno, Vidic, Jasmina, Descamps, Delphyne, Sallenave, Jean-Michel, Rauch, Michel, Samson, Michel, Delmas, Bernard

“…Airway inflammation plays a major role in the pathogenesis of influenza viruses and can lead to a fatal outcome. One of the challenging objectives in the field…”
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Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral Attenuation by Da Costa, Bruno, Sausset, Alix, Munier, Sandie, Ghounaris, Alexandre, Naffakh, Nadia, Le Goffic, Ronan, Delmas, Bernard

“…The influenza virus RNA-dependent RNA polymerase catalyzes genome replication and transcription within the cell nucleus. Efficient nuclear import and assembly…”
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Humoral Responses Elicited by Adenovirus Displaying Epitopes Are Induced Independently of the Infection Process and Shaped by the Toll-Like Receptor/MyD88 Pathway by Anchim, Aleksandra, Raddi, Najat, Zig, Lena, Perrieau, Patrick, Le Goffic, Ronan, Ryffel, Bernhard, Benihoud, Karim

“…The use of serotype 5 adenovirus (Ad)-derived vectors in vaccination is confronted to preexisting anti-Ad immunity. Epitope display on Ad capsid is currently…”
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Influenza infection rewires energy metabolism and induces browning features in adipose cells and tissues by Ayari, Asma, Rosa-Calatrava, Manuel, Lancel, Steve, Barthelemy, Johanna, Pizzorno, Andrés, Mayeuf-Louchart, Alicia, Baron, Morgane, Hot, David, Deruyter, Lucie, Soulard, Daphnée, Julien, Thomas, Faveeuw, Christelle, Molendi-Coste, Olivier, Dombrowicz, David, Sedano, Laura, Sencio, Valentin, Le Goffic, Ronan, Trottein, François, Wolowczuk, Isabelle

“…Like all obligate intracellular pathogens, influenza A virus (IAV) reprograms host cell’s glucose and lipid metabolism to promote its own replication. However,…”
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A condensate-hardening drug blocks RSV replication in vivo by Risso-Ballester, Jennifer, Galloux, Marie, Cao, Jingjing, Le Goffic, Ronan, Hontonnou, Fortune, Jobart-Malfait, Aude, Desquesnes, Aurore, Sake, Svenja M., Haid, Sibylle, Du, Miaomiao, Zhang, Xiumei, Zhang, Huanyun, Wang, Zhaoguo, Rincheval, Vincent, Zhang, Youming, Pietschmann, Thomas, Eléouët, Jean-François, Rameix-Welti, Marie-Anne, Altmeyer, Ralf

“…Biomolecular condensates have emerged as an important subcellular organizing principle 1 . Replication of many viruses, including human respiratory syncytial…”
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Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production by Sencio, Valentin, Barthelemy, Adeline, Tavares, Luciana P., Machado, Marina G., Soulard, Daphnée, Cuinat, Céline, Queiroz-Junior, Celso Martins, Noordine, Marie-Louise, Salomé-Desnoulez, Sophie, Deryuter, Lucie, Foligné, Benoit, Wahl, Céline, Frisch, Benoit, Vieira, Angelica T., Paget, Christophe, Milligan, Graeme, Ulven, Trond, Wolowczuk, Isabelle, Faveeuw, Christelle, Le Goffic, Ronan, Thomas, Muriel, Ferreira, Stéphanie, Teixeira, Mauro M., Trottein, François

“…Secondary bacterial infections often complicate viral respiratory infections. We hypothesize that perturbation of the gut microbiota during influenza A virus…”
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Edema toxin impairs anthracidal phospholipase A2 expression by alveolar macrophages by Raymond, Benoit, Leduc, Dominique, Ravaux, Lucas, Le Goffic, Ronan, Candela, Thomas, Raymondjean, Michel, Goossens, Pierre Louis, Touqui, Lhousseine

“…Bacillus anthracis, the etiological agent of anthrax, is a spore-forming gram-positive bacterium. Infection with this pathogen results in multisystem…”
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Influenza Virus Infection Impairs the Gut's Barrier Properties and Favors Secondary Enteric Bacterial Infection through Reduced Production of Short-Chain Fatty Acids by Sencio, Valentin, Gallerand, Alexandre, Gomes Machado, Marina, Deruyter, Lucie, Heumel, Séverine, Soulard, Daphnée, Barthelemy, Johanna, Cuinat, Céline, Vieira, Angelica T, Barthelemy, Adeline, Tavares, Luciana P, Guinamard, Rodolphe, Ivanov, Stoyan, Grangette, Corinne, Teixeira, Mauro M, Foligné, Benoit, Wolowczuk, Isabelle, Le Goffic, Ronan, Thomas, Muriel, Trottein, François

“…Along with respiratory tract disease , viral respiratory infections can also cause extrapulmonary complications with a potentially critical impact on health…”
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Influenza virus protein PB1-F2 interacts with CALCOCO2 (NDP52) to modulate innate immune response by Leymarie, Olivier, Meyer, Léa, Tafforeau, Lionel, Lotteau, Vincent, Costa, Bruno Da, Delmas, Bernard, Chevalier, Christophe, Le Goffic, Ronan

“…PB1-F2 is a viral protein encoded by influenza A viruses (IAVs). PB1-F2 is implicated in virulence by triggering immune cell apoptosis and enhancing…”
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Cutting Edge: Influenza A Virus Activates TLR3-Dependent Inflammatory and RIG-I-Dependent Antiviral Responses in Human Lung Epithelial Cells by Le Goffic, Ronan, Pothlichet, Julien, Vitour, Damien, Fujita, Takashi, Meurs, Eliane, Chignard, Michel, Si-Tahar, Mustapha

“…Influenza A virus (IAV) triggers a contagious acute respiratory disease that causes considerable mortality annually. Recently, we established a role for the…”
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Respiratory syncytial virus tropism for olfactory sensory neurons in mice by Bryche, Bertrand, Frétaud, Maxence, Saint‐Albin Deliot, Audrey, Galloux, Marie, Sedano, Laura, Langevin, Christelle, Descamps, Delphyne, Rameix‐Welti, Marie‐Anne, Eléouët, Jean‐François, Le Goffic, Ronan, Meunier, Nicolas

“…The olfactory mucosa, where the first step of odor detection occurs, is a privileged pathway for environmental toxicants and pathogens toward the central…”
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Involvement of Toll-like Receptor 3 in the Immune Response of Lung Epithelial Cells to Double-stranded RNA and Influenza A Virus by Guillot, Loïc, Le Goffic, Ronan, Bloch, Sarah, Escriou, Nicolas, Akira, Shizuo, Chignard, Michel, Si-Tahar, Mustapha

“…Influenza A is a highly contagious single-stranded RNA virus that infects both the upper and lower respiratory tracts of humans. The host innate immune…”
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Non-Steroidal Estrogens Inhibit Influenza Virus by Interacting with Hemagglutinin and Preventing Viral Fusion by Franzi, Elisa, Mathez, Gregory, Dinant, Soraya, Deloizy, Charlotte, Kaiser, Laurent, Tapparel, Caroline, Le Goffic, Ronan, Cagno, Valeria

“…Influenza virus is one of the main causes of respiratory infections worldwide. Despite the availability of seasonal vaccines and antivirals, influenza virus…”
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Visualizing the replication of respiratory syncytial virus in cells and in living mice by Rameix-Welti, Marie-Anne, Le Goffic, Ronan, Hervé, Pierre-Louis, Sourimant, Julien, Rémot, Aude, Riffault, Sabine, Yu, Qin, Galloux, Marie, Gault, Elyanne, Eléouët, Jean-François

“…Respiratory syncytial virus (RSV) is the most important cause of severe lower-respiratory tract disease in calves and young children, yet no human vaccine nor…”
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