Search Results - "Le Gall‐Ianotto, Christelle"

New human in vitro co-culture model of keratinocytes and sensory neurons like cells releasing substance P with an evaluation of the expression of ZIKV entry receptors: A potent opportunity to test Zika virus entry and to study Zika virus' infection in neurons? by Bocciarelli, Claire, Cordel, Nadège, Leschiera, Raphael, Talagas, Matthieu, Le Gall-Ianotto, Christelle, Hu, Weiguo, Marcorelles, Pascale, Bellemere, Gaëlle, Bredif, Stéphanie, Fluhr, Joachim, Misery, Laurent, Lebonvallet, Nicolas

“…During the course of acute ZIKV infection, pruritus is a cardinal symptom widely documented in the literature. Its frequent association with dysesthesia and…”
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Do Merkel complexes initiate mechanical itch? by Bataille‐Savattier, Adeline, Le Gall‐Ianotto, Christelle, Lebonvallet, Nicolas, Misery, Laurent, Talagas, Matthieu

“…Itch is a common sensation which is amenable to disabling patients' life under pathological and chronic conditions. Shared assertion easily limits itch to…”
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Chronic itch: emerging treatments following new research concepts by Misery, Laurent, Brenaut, Emilie, Pierre, Ophélie, Le Garrec, Raphaele, Gouin, Olivier, Lebonvallet, Nicolas, Abasq‐Thomas, Claire, Talagas, Matthieu, Le Gall‐Ianotto, Christelle, Besner‐Morin, Catherine, Fluhr, Joachim W., Leven, Cyril

“…Until recently, itch pathophysiology was poorly understood and treatments were poorly effective in relieving itch. Current progress in our knowledge of the…”
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Re‐innervation of human skin by rat dorsal root ganglia permits to study interactions between sensory nerve fibres and native human dermal mast cells ex vivo by Chéret, Jérémy, Ponce, Leslie, Le Gall‐Ianotto, Christelle, Bertolini, Marta, PAUS, RALF

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Differences between aquagenic and non‐aquagenic pruritus in myeloproliferative neoplasms: An observational study of 500 patients by Le Gall‐Ianotto, Christelle, Ficheux, Anne‐Sophie, Lippert, Eric, Herbreteau, Laura, Rio, Laetitia, Pan‐Petesch, Brigitte, Misery, Laurent, Ianotto, Jean‐Christophe

“…Background Pruritus is a frequent symptom experienced by patients with myeloproliferative neoplasms (MPN). Aquagenic pruritus (AP) is the most common type. The…”
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Aquagenic pruritus in essential thrombocythemia is associated with a higher risk of thrombosis by Le Gall‐Ianotto, Christelle, Le Calloch, Ronan, Couturier, Marie‐Anne, Chauveau, Aurélie, Lippert, Eric, Carré, Jean‐Luc, Misery, Laurent, Ianotto, Jean‐Christophe

“…Background Thromboses and phenotypic evolutions (leukemia, myelofibrosis) are the most frequent complications in polycythemia vera (PV) and essential…”
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Role of neuropeptides, neurotrophins, and neurohormones in skin wound healing by Chéret, Jérémy, Lebonvallet, Nicolas, Carré, Jean-Luc, Misery, Laurent, Le Gall-Ianotto, Christelle

“…Due to the close interactions between the skin and peripheral nervous system, there is increasing evidence that the cutaneous innervation is an important…”
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Self-maintenance of neurogenic inflammation contributes to a vicious cycle in skin by Gouin, Olivier, Lebonvallet, Nicolas, L'Herondelle, Killian, Le Gall-Ianotto, Christelle, Buhé, Virginie, Plée-Gautier, Emmanuelle, Carré, Jean-Luc, Lefeuvre, Luc, Misery, Laurent

“…Cutaneous neurogenic inflammation (CNI) is frequently associated with skin disorders. CNI is not limited to the retrograde signalling of nociceptive sensory…”
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A new tool to test active ingredient using lactic acid in vitro, a help to understand cellular mechanism involved in stinging test: An example using a bacterial polysaccharide (Fucogel®) by Sakka, Mehdi, Leschiera, Raphael, Le Gall‐Ianotto, Christelle, Gouin, Olivier, L'herondelle, Killian, Buscaglia, Paul, Mignen, Olivier, Philbé, Jean‐Luc, Saguet, Thibaut, Carré, Jean‐Luc, Misery, Laurent, Lebonvallet, Nicolas

“…The stinging test is an in vivo protocol that evaluates sensitive skin using lactic acid (LA). A soothing sensation of cosmetics or ingredients can be also…”
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TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation： pro-inflammatory response induced by their activation and their sensitization by Gouin, Olivier, L’Herondelle, Killian, Lebonvallet, Nicolas, Le Gall-Ianotto, Christelle, Sakka, Mehdi, Buhé, Virginie, Plée-Gautier, Emmanuelle, Carré, Jean-Luc, Lefeuvre, Luc, Misery, Laurent, Le Garrec, Raphaele

“…Cutaneous neurogenic inflammation （CNI） is inflammation that is induced （or enhanced） in the skin by the release of neuropeptides from sensory nerve endings…”
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Pathophysiology and management of sensitive skin: position paper from the special interest group on sensitive skin of the International Forum for the Study of Itch (IFSI) by Misery, L., Weisshaar, E., Brenaut, E., Evers, A.W.M., Huet, F., Ständer, S., Reich, A., Berardesca, E., Serra‐Baldrich, E., Wallengren, J., Linder, D., Fluhr, J.W., Szepietowski, J.C., Maibach, H., Honari, Golara, Le Gall‐Ianotto, Christelle, Takamori, Kenji, Richters, Renée

“…The special interest group on sensitive skin of the International Forum for the Study of Itch previously defined sensitive skin as a syndrome defined by the…”
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Major Role for TRPV1 and InsP3R in PAR2-Elicited Inflammatory Mediator Production in Differentiated Human Keratinocytes by Gouin, Olivier, L'Herondelle, Killian, Buscaglia, Paul, Le Gall-Ianotto, Christelle, Philippe, Réginald, Legoux, Nelig, Mignen, Olivier, Buhé, Virginie, Leschiera, Raphael, Sakka, Mehdi, Kerfant, Nathalie, Carré, Jean-Luc, Le Garrec, Raphaele, Lefeuvre, Luc, Lebonvallet, Nicolas, Misery, Laurent

“…PAR2 activation in basal keratinocytes stimulates inflammation via the Ca2+-dependent production of mediators such as IL-1β, TNF-α, and TSLP. In this study, we…”
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Sensitive Skin: Lessons From Transcriptomic Studies by Bataille, Adeline, Le Gall-Ianotto, Christelle, Genin, Emmanuelle, Misery, Laurent

“…In 2016, a special interest group from the International Forum for the Study of Itch defined sensitive skin (SS) as a syndrome that manifests with the…”
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Non-adherence to treatment with cytoreductive and/or antithrombotic drugs is frequent and associated with an increased risk of complications in patients with polycythemia vera or essential thrombocythemia (OUEST study) by Le Calloch, Ronan, Lacut, Karine, Le Gall-Ianotto, Christelle, Nowak, Emmanuel, Abiven, Morgane, Tempescul, Adrian, Dalbies, Florence, Eveillard, Jean-Richard, Ugo, Valérie, Giraudier, Stéphane, Guillerm, Gaëlle, Lippert, Eric, Berthou, Christian, Ianotto, Jean-Christophe

“…The purpose of this study was to identify the incidence, causes and impact of non-adherence to oral and subcutaneous chronic treatments for patients with…”
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Sensitive Skin Syndrome: A Low-Noise Small-Fiber Neuropathy Related to Environmental Factors? by Misery, Laurent, Bataille, Adeline, Talagas, Matthieu, Le Gall-Ianotto, Christelle, Fouchard, Maxime, Huet, Flavien, Ficheux, Anne-Sophie, Roudot, Alain-Claude, Fluhr, Joachim W, Brenaut, Emilie

“…Patients frequently complain of mild, transient, unpleasant skin sensations that cannot be diagnosed as common neuropathies. Dermatologists have termed these…”
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Major Role for TRPV1 and InsP3R in PAR2-Elicited Inflammatory Mediator Production in Differentiated Human Keratinocytes by Misery, Laurent, Brenaut, Emilie, Pierre, Ophélie, Le Garrec, Raphaele, Gouin, Olivier, Lebonvallet, Nicolas, Abasq‐thomas, Claire, Talagas, Matthieu, Le Gall‐ianotto, Christelle, Besner‐morin, Catherine, Fluhr, Joachim, Leven, Cyril, Chéret, Jérémy, Ponce, Leslie, Bertolini, Marta, Paus, Ralf, L’herondelle, Killian, Fouyet, Sophie, Leschiera, Raphael, Le Gall-Ianotto, Christelle, Philippe, Reginald, Buscaglia, Paul, Mignen, Olivier, Lewis, Richard, Michel, Laurence, Devergne, C., Kerspern, H., Poizeau, F., Eveillard, J.R., Carré, J.L., Weisshaar, E., Evers, A.W.M., Huet, F., Ständer, S., Reich, A., Berardesca, E., Serra‐baldrich, E., Wallengren, J., Linder, D., Fluhr, J.W., Szepietowski, J.C., Maibach, H., Honari, Golara, Takamori, Kenji, Richters, Renée, Barnetche, T., Roudot, A.‐c., Ficheux, A.‐s., Le Calloch, Ronan, Couturier, Marie‐anne, Chauveau, Aurélie, Lippert, Eric, Carré, Jean‐luc, Ianotto, Jean‐christophe, Bataille, Adeline, Genin, Emmanuelle, L'Herondelle, Killian, Legoux, Nelig, Buhé, Virginie, Sakka, Mehdi, Kerfant, Nathalie, Lefeuvre, Luc

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Expression of neuroserpin, a selective inhibitor of tissue-type plasminogen activator in the human skin by Chéret, Jérémy, Lebonvallet, Nicolas, Misery, Laurent, Le Gall-Ianotto, Christelle

“…Serine protease of the fibrinolytic system and their specific inhibitors, the serine protease inhibitors (SERPINs) are implicated in a number of physiological…”
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Comparative transcriptional profiling of human Merkel cells and Merkel cell carcinoma by Mouchet, Nicolas, Coquart, Nolwenn, Lebonvallet, Nicolas, Le Gall-Ianotto, Christelle, Mogha, Ariane, Fautrel, Alain, Boulais, Nicholas, Dréno, Brigitte, Martin, Ludovic, Hu, Weiguo, Galibert, Marie-Dominique, Misery, Laurent

“…Merkel cell carcinoma is believed to be derived from Merkel cells after infection by Merkel cell polyomavirus (MCPyV) and other poorly understood events…”
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Activation of primary sensory neurons by the topical application of capsaicin on the epidermis of a re-innervated organotypic human skin model by Lebonvallet, Nicolas, Pennec, Jean-Pierre, Le Gall-Ianotto, Christelle, Chéret, Jérémy, Jeanmaire, Christine, Carré, Jean-Luc, Pauly, Gilles, Misery, Laurent

“…Using an ex vivo skin‐nerve preparation, skin and nerve cells were reconstituted into a single unit and maintained in a nutrient medium bath until required…”
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Basic mechanisms of itch by Misery, Laurent, Pierre, Ophélie, Le Gall-Ianotto, Christelle, Lebonvallet, Nicolas, Chernyshov, Pavel V., Le Garrec, Raphaële, Talagas, Matthieu

“…Pruritus (or itch) is an unpleasant sensation leading to a desire to scratch. In the epidermis, there are selective C or Aδ epidermal nerve endings that are…”
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