Search Results - "Le Dily, Séverine"
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Heterogeneous pattern of autonomic dysfunction in Parkinson’s disease
Published in Journal of neurology (01-04-2018)“…Dysautonomic symptoms are frequent non-motor complaints in patients with Parkinson’s disease. Numerous neuropathological studies have shown that Lewy bodies…”
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2
Randomized Placebo-controlled Trial of Sodium Valproate in Progressive Supranuclear Palsy
Published in Clinical neurology and neurosurgery (01-07-2016)“…Highlights • Inhibition of glycogen synthase kinase (GSK-3) is a therapeutic option for PSP. • We assessed the safety and efficacy of sodium valproate (VPA), a…”
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3
Wake and non-rapid eye movement sleep dysfunction is associated with colonic neuropathology in Parkinson’s disease
Published in Sleep (New York, N.Y.) (01-03-2024)“…Abstract Study Objectives The body-first Parkinson’s disease (PD) hypothesis suggests initial gut Lewy body pathology initially propagates to the pons before…”
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4
Structural alterations of the intestinal epithelial barrier in Parkinson's disease
Published in Acta neuropathologica communications (10-03-2015)“…Functional and morphological alterations of the intestinal epithelial barrier (IEB) have been consistently reported in digestive disorders such as irritable…”
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LeSCoD: a new clinical scale for the detection of Lewy body disease in neurocognitive disorders
Published in Journal of neurology (01-10-2021)“…Background Dementia with Lewy bodies remains underdiagnosed in clinical practice mainly because of the low sensitivity of existing diagnostic criteria and a…”
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REM sleep behavior disorder is related to enteric neuropathology in Parkinson disease
Published in Neurology (10-10-2017)“…OBJECTIVE:To determine whether REM sleep behavior disorder (RBD) in Parkinson disease (PD) is associated with lesions and dysfunctions of the autonomic nervous…”
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A Double‐Blind, Randomized, Placebo‐Controlled Trial of Bumetanide in Parkinson's Disease
Published in Movement disorders (01-03-2024)“…Background Acting on the main target of dopaminergic cells, the striatal γ‐aminobutyric acid (GABA)‐ergic cells, might be a new way to treat persons with…”
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Colonic neuropathology is not associated with autonomic dysfunction in Parkinson's disease
Published in Parkinsonism & related disorders (01-04-2019)“…Dysautonomia in Parkinson's disease (PD) has been shown to be associated with disease severity and especially with the occurrence of dementia. One proposed…”
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LeSCoD : une nouvelle échelle clinique de détection des signes de pathologie de Lewy
Published in Revue neurologique (01-04-2019)“…La pathologie à corps de Lewy reste sous diagnostiquée en pratique courante du fait d’un manque de sensibilité des critères diagnostiques et d’une intrication…”
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Existe-t-il une corrélation entre les signes cliniques de la pathologie à corps de Lewy et la fonction dopaminergique dans le spectre maladie d’Alzheimer–maladie à corps de Lewy ? Résultats de quantification en TEP à la 18F-DOPA sur 10 patients
Published in Revue neurologique (01-04-2016)“…Les critères diagnostiques actuels de maladie à corps de Lewy (MCL) ne tiennent pas compte du chevauchement clinique et histopathologique entre MCL et maladie…”
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