Search Results - "Le Dévéhat, Maïlys"
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SKI-1/S1P Facilitates SARS-CoV-2 Spike Induced Cell-to-Cell Fusion via Activation of SREBP-2 and Metalloproteases, Whereas PCSK9 Enhances the Degradation of ACE2
Published in Viruses (27-01-2023)“…Proprotein convertases activate various envelope glycoproteins and participate in cellular entry of many viruses. We recently showed that the convertase furin…”
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Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels
Published in Molecular metabolism (Germany) (01-01-2023)“…The liver-derived circulating PCSK9 enhances the degradation of the LDL receptor (LDLR) in endosomes/lysosomes. PCSK9 inhibition or silencing is presently used…”
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PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease
Published in Metabolism, clinical and experimental (01-01-2024)“…Epidemiological evidence links the proprotein convertase subtilisin/kexin 7 (PCSK7) to triglyceride (TG) metabolism. We associated the known PCSK7…”
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