Search Results - "Le Coz, Madeleine"
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Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair
Published in Cell (08-07-2011)“…DNA methylation is a major epigenetic mechanism for gene silencing. Whereas methyltransferases mediate cytosine methylation, it is less clear how unmethylated…”
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Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells
Published in PLoS genetics (01-10-2015)“…MIcrophthalmia-associated Transcription Factor (MITF) regulates melanocyte and melanoma physiology. We show that MITF associates the NURF chromatin-remodelling…”
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BRN2 is a non-canonical melanoma tumor-suppressor
Published in Nature communications (17-06-2021)“…While the major drivers of melanoma initiation, including activation of NRAS/BRAF and loss of PTEN or CDKN2A , have been identified, the role of key…”
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SUPREM: an engineered non-site-specific m6A RNA methyltransferase with highly improved efficiency
Published in Nucleic acids research (17-10-2024)“…N 6-Methyladenine (m6A) RNA methylation plays a key role in RNA processing and translational regulation, influencing both normal physiological and pathological…”
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Quiescent melanocytes form primary cilia
Published in Experimental dermatology (01-06-2014)“…We show, for the first time, that melanocytes can form a primary cilium in vitro, corresponding to an immotile or sensory cilium. Such cilia are observed when…”
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Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells: e1005555
Published in PLoS genetics (01-10-2015)“…MIcrophthalmia-associated Transcription Factor (MITF) regulates melanocyte and melanoma physiology. We show that MITF associates the NURF chromatin-remodelling…”
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