Search Results - "Le Chatelier, Emmanuelle"
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Alterations of the human gut microbiome in liver cirrhosis
Published in Nature (London) (04-09-2014)“…Liver cirrhosis occurs as a consequence of many chronic liver diseases that are prevalent worldwide. Here we characterize the gut microbiome in liver cirrhosis…”
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Dissemination of the mcr-1 colistin resistance gene
Published in The Lancet infectious diseases (01-03-2016)“…[...]we showed that the newly described mcr-1 gene has been disseminating in China since before 2010, as a mobile form…”
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Four functional profiles for fibre and mucin metabolism in the human gut microbiome
Published in Microbiome (20-10-2023)“…With the emergence of metagenomic data, multiple links between the gut microbiome and the host health have been shown. Deciphering these complex interactions…”
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Major depletion of insulin sensitivity-associated taxa in the gut microbiome of persons living with HIV controlled by antiretroviral drugs
Published in BMC medical genomics (13-08-2024)“…Persons living with HIV (PWH) harbor an altered gut microbiome (higher abundance of Prevotella and lower abundance of Bacillota and Ruminococcus lineages)…”
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High engraftment capacity of frozen ready-to-use human fecal microbiota transplants assessed in germ-free mice
Published in Scientific reports (23-02-2021)“…The number of indications for fecal microbiota transplantation is expected to rise, thus increasing the needs for production of readily available frozen or…”
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Interactions of the Bacillus subtilis DnaE polymerase with replisomal proteins modulate its activity and fidelity
Published in Open biology (01-09-2017)“…During Bacillus subtilis replication two replicative polymerases function at the replisome to collectively carry out genome replication. In a reconstituted in…”
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Changes in Gut Microbiota of Patients with Atopic Dermatitis During Balneotherapy
Published in Clinical, cosmetic and investigational dermatology (01-01-2022)“…Balneotherapy (BT) is the treatment of disease through the use of thermal spring water (TSW). It has been used for centuries and remains a popular form of…”
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8
Genetic evidence for a link between glycolysis and DNA replication
Published in PloS one (16-05-2007)“…A challenging goal in biology is to understand how the principal cellular functions are integrated so that cells achieve viability and optimal fitness in a…”
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Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology
Published in Gut (01-03-2016)“…Individuals with obesity and type 2 diabetes differ from lean and healthy individuals in their abundance of certain gut microbial species and microbial gene…”
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Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer
Published in Nature Medicine (01-02-2022)“…Aside from PD-L1 expression, biomarkers of response to immune checkpoint inhibitors (ICIs) in non-small-cell lung cancer (NSCLC) are needed. In a previous…”
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Major microbiota dysbiosis in severe obesity: fate after bariatric surgery
Published in Gut (01-01-2019)“…Decreased gut microbial gene richness (MGR) and compositional changes are associated with adverse metabolism in overweight or moderate obesity, but lack…”
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Human gut microbes impact host serum metabolome and insulin sensitivity
Published in Nature (London) (21-07-2016)“…Increased potential for branched-chain amino acid and lipopolysaccharide biosynthesis in the gut microbiome of insulin-resistant individuals suggests that…”
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Towards standards for human fecal sample processing in metagenomic studies
Published in Nature biotechnology (01-11-2017)“…Testing 21 different fecal DNA extraction protocols in multiple laboratories results in a standardized protocol with the potential to improve comparability…”
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Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis
Published in Genome Biology (27-07-2017)“…The assessment and characterization of the gut microbiome has become a focus of research in the area of human autoimmune diseases. Ankylosing spondylitis is an…”
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Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson’s disease
Published in Cell reports (Cambridge) (02-03-2021)“…Parkinson’s disease (PD) is the most common progressive neurological disorder compromising motor functions. However, nonmotor symptoms, such as…”
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Dietary intervention impact on gut microbial gene richness
Published in Nature (London) (29-08-2013)“…In obese and overweight individuals, diet-induced weight loss and weight-stabilization interventions improve the low microbiota gene richness and clinical…”
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MSPminer: abundance-based reconstitution of microbial pan-genomes from shotgun metagenomic data
Published in Bioinformatics (Oxford, England) (01-05-2019)“…Analysis toolkits for shotgun metagenomic data achieve strain-level characterization of complex microbial communities by capturing intra-species gene content…”
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A Natural Polyphenol Exerts Antitumor Activity and Circumvents Anti-PD-1 Resistance through Effects on the Gut Microbiota
Published in Cancer discovery (01-04-2022)“…Several approaches to manipulate the gut microbiome for improving the activity of cancer immune-checkpoint inhibitors (ICI) are currently under evaluation…”
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A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers
Published in Science (American Association for the Advancement of Science) (09-06-2023)“…Antibiotics (ABX) compromise the efficacy of programmed cell death protein 1 (PD-1) blockade in cancer patients, but the mechanisms underlying their…”
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Protection of the Human Gut Microbiome From Antibiotics
Published in The Journal of infectious diseases (30-01-2018)“…In a phase 1 clinical study, coadministration of the adsorbent-based DAV132 product together with the fluoroquinolone antibiotic moxifloxacin, while not…”
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