Search Results - "Le Bihan, Denis"
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Apparent diffusion coefficient and beyond: what diffusion MR imaging can tell us about tissue structure
Published in Radiology (01-08-2013)Get full text
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Diffusion MRI at 25: Exploring brain tissue structure and function
Published in NeuroImage (Orlando, Fla.) (01-06-2012)“…Diffusion MRI (or dMRI) came into existence in the mid-1980s. During the last 25years, diffusion MRI has been extraordinarily successful (with more than…”
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Diffusion-weighted imaging of the breast—a consensus and mission statement from the EUSOBI International Breast Diffusion-Weighted Imaging working group
Published in European radiology (01-03-2020)“…The European Society of Breast Radiology (EUSOBI) established an International Breast DWI working group. The working group consists of clinical breast MRI…”
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Diffusion MRI reveals in vivo and non-invasively changes in astrocyte function induced by an aquaporin-4 inhibitor
Published in PloS one (15-05-2020)“…The Glymphatic System (GS) has been proposed as a mechanism to clear brain tissue from waste. Its dysfunction might lead to several brain pathologies,…”
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What can we see with IVIM MRI?
Published in NeuroImage (Orlando, Fla.) (15-02-2019)“…Intravoxel Incoherent Motion (IVIM) refers to translational movements which within a given voxel and during the measurement time present a distribution of…”
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Mesoscopic and microscopic imaging of sensory responses in the same animal
Published in Nature communications (07-03-2019)“…Imaging based on blood flow dynamics is widely used to study sensory processing. Here we investigated the extent to which local neuronal and capillary…”
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Diffusion functional MRI reveals global brain network functional abnormalities driven by targeted local activity in a neuropsychiatric disease mouse model
Published in NeuroImage (Orlando, Fla.) (01-12-2020)“…•Hemodynamic-independent measurement of DfMRI is key to detect brain dysfunction.•We detected hyperactivation of the CST circuit in a neuropsychiatric mouse…”
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Differential effects of aquaporin-4 channel inhibition on BOLD fMRI and diffusion fMRI responses in mouse visual cortex
Published in PloS one (21-05-2020)“…The contribution of astrocytes to the BOLD fMRI and DfMRI responses in visual cortex of mice following visual stimulation was investigated using TGN-020, an…”
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DIFFUSION MRI of the BREAST
Published 2022“…Diffusion weighted imaging (DWI) is a key emerging imaging modality for the management of patients with possible breast lesions, and Diffusion MRI of the…”
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Correction: Diffusion Magnetic Resonance Imaging: What Water Tells Us about Biological Tissues
Published in PLoS biology (03-09-2015)“…[This corrects the article DOI: 10.1371/journal.pbio.1002203.]…”
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Investigation of breast cancer microstructure and microvasculature from time-dependent DWI and CEST in correlation with histological biomarkers
Published in Scientific reports (20-04-2022)“…We investigated the associations of time-dependent DWI, non-Gaussian DWI, and CEST parameters with histological biomarkers in a breast cancer xenograft model…”
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Clinical Intravoxel Incoherent Motion and Diffusion MR Imaging: Past, Present, and Future
Published in Radiology (01-01-2016)“…The concept of diffusion magnetic resonance (MR) imaging emerged in the mid-1980s, together with the first images of water diffusion in the human brain, as a…”
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Direct and Fast Detection of Neuronal Activation in the Human Brain with Diffusion MRI
Published in Proceedings of the National Academy of Sciences - PNAS (23-05-2006)“…Using MRI, we found that a slowly diffusing water pool was expanding (1.7 ± 0.3%) upon activation on the human visual cortex at the detriment of a faster…”
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Spatial contribution of hippocampal BOLD activation in high-resolution fMRI
Published in Scientific reports (28-02-2019)“…While the vascular origin of the BOLD-fMRI signal is established, the exact neurovascular coupling events contributing to this signal are still incompletely…”
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In Vivo and Post-mortem Comparisons of IVIM/Time-dependent Diffusion MR Imaging Parameters in Melanoma and Breast Cancer Xenograft Models
Published in Magnetic Resonance in Medical Sciences (2024)“…Purpose: We aimed to investigate the changes in intravoxel incoherent motion (IVIM) and diffusion parameters between in vivo and post-mortem conditions and the…”
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Task-specific change of unconscious neural priming in the cerebral language network
Published in Proceedings of the National Academy of Sciences - PNAS (04-12-2007)“…We explored the impact of task context on subliminal neural priming using functional magnetic resonance imaging. The repetition of words during semantic…”
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Subliminal convergence of Kanji and Kana words: further evidence for functional parcellation of the posterior temporal cortex in visual word perception
Published in Journal of cognitive neuroscience (01-06-2005)“…Recent evidence has suggested that the human occipitotemporal region comprises several subregions, each sensitive to a distinct processing level of visual…”
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Diffusion MRI: what water tells us about the brain
Published in EMBO molecular medicine (01-05-2014)“…Diffusion MRI has been used worldwide to produce images of brain tissue structure and connectivity, in the normal and diseased brain. Diffusion MRI has…”
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The 'wet mind': water and functional neuroimaging
Published in Physics in medicine & biology (07-04-2007)“…Functional neuroimaging has emerged as an important approach to study the brain and the mind. Surprisingly, although they are based on radically different…”
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An intrinsic diffusion response function for analyzing diffusion functional MRI time series
Published in NeuroImage (Orlando, Fla.) (01-10-2009)“…To disentangle the temporal profiles of the diffusion and BOLD components of diffusion-weighted functional MRI (DfMRI) during visual activation, we extracted…”
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