Search Results - "Le Beyec, Johanne"
-
1
Bariatric surgery induces a new gastric mucosa phenotype with increased functional glucagon-like peptide-1 expressing cells
Published in Nature communications (04-01-2021)“…Glucagon-Like Peptide-1 (GLP-1) undergoes rapid inactivation by dipeptidyl peptidase-4 (DPP4) suggesting that target receptors may be activated by locally…”
Get full text
Journal Article -
2
Shortening the Biliopancreatic Limb Length of One Anastomosis Gastric Bypass Maintains Glucose Homeostasis Improvement with Limited Weight Loss
Published in Journal of clinical medicine (01-09-2022)“…One anastomosis gastric bypass (OAGB) is associated with similar metabolic improvements and weight loss as Roux-en-Y gastric bypass (RYGB). However, this…”
Get full text
Journal Article -
3
Orosensory Perception of Fat/Sweet Stimuli and Appetite-Regulating Peptides before and after Sleeve Gastrectomy or Gastric Bypass in Adult Women with Obesity
Published in Nutrients (08-03-2021)“…The aim of this study was to explore the impact of bariatric surgery on fat and sweet taste perceptions and to determine the possible correlations with gut…”
Get full text
Journal Article -
4
Hepatocyte Nuclear Factor 4α, a Key Factor for Homeostasis, Cell Architecture, and Barrier Function of the Adult Intestinal Epithelium
Published in Molecular and Cellular Biology (01-12-2009)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
5
Long-Term Weight Outcome After Bariatric Surgery in Patients with Melanocortin-4 Receptor Gene Variants: a Case–Control Study of 105 Patients
Published in Obesity surgery (01-03-2022)“…Introduction Pathogenic heterozygous MC4R variants are associated with hyperphagia and variable degrees of obesity. Several research groups have reported…”
Get full text
Journal Article -
6
Intestinal adaptation in short bowel syndrome. What is new?
Published in Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral (17-05-2018)“…Short bowel syndrome (SBS) is a well-known cause of intestinal failure (IF) (1). SBS occurs after extensive resection of the small bowel (RSB) resulting in a…”
Get full text
Journal Article -
7
Implication of Heterozygous Variants in Genes of the Leptin-Melanocortin Pathway in Severe Obesity
Published in The journal of clinical endocrinology and metabolism (01-10-2021)“…Unlike homozygous variants, the implication of heterozygous variants on the leptin-melanocortin pathway in severe obesity has not been established. To describe…”
Get full text
Journal Article -
8
Epidermal growth factor receptor is involved in enterocyte anoikis through the dismantling of E-cadherin-mediated junctions
Published in American journal of physiology: Gastrointestinal and liver physiology (01-02-2009)“…Enterocytes of the intestinal epithelium are continually regenerated. They arise from precursor cells in crypts, migrate along villi, and finally die, 3-4 days…”
Get more information
Journal Article -
9
Unexpected upper gastrointestinal polyps in patients with short bowel syndrome treated with teduglutide: need for close monitoring
Published in The American journal of clinical nutrition (01-06-2023)“…Teduglutide is a GLP-2 analog indicated for the treatment of short bowel syndrome (SBS) since 2015. Its efficacy in reducing parenteral nutrition (PN) has been…”
Get full text
Journal Article -
10
A novel pathogenic variant in MRAP2 in an obese patient with successful outcome of bariatric surgery
Published in European journal of endocrinology (17-10-2023)“…Abstract Mutations in genes encoding proteins located in the leptin/melanocortin pathway have been identified in the rare cases of genetic obesities…”
Get full text
Journal Article -
11
Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency
Published in Molecular metabolism (Germany) (01-10-2017)“…Pro-opiomelanocortin (POMC)-derived peptides act on neurons expressing the Melanocortin 4 receptor (MC4R) to reduce body weight. Setmelanotide is a highly…”
Get full text
Journal Article -
12
Similar Gut Hormone Secretions Two Years After One Anastomosis Gastric Bypass and Roux-en-Y Gastric Bypass: a Pilot Study
Published in Obesity surgery (01-03-2022)“…Objectives One-anastomosis gastric bypass (OAGB) is as effective as Roux-en-Y gastric bypass (RYGB) regarding weight loss and diabetes remission. However,…”
Get full text
Journal Article -
13
Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery
Published in PloS one (21-11-2012)“…Bariatric surgery is the most effective long term weight-loss therapy for severe and morbidly obese patients. Melanocortin-4 Receptor (MC4R) mutations, the…”
Get full text
Journal Article -
14
Circulating Apolipoprotein B-48 as a Biomarker of Parenteral Nutrition Dependence in Adult Patients with Short Bowel Syndrome
Published in Nutrients (01-09-2023)“…Short bowel syndrome (SBS) is a rare but serious condition that may lead to chronic intestinal failure. Citrulline concentrations are currently used to reflect…”
Get full text
Journal Article -
15
Fecal microbiota transplantation in a rodent model of short bowel syndrome: A therapeutic approach?
Published in Frontiers in cellular and infection microbiology (2023)“…Extensive intestinal resection leads to Short Bowel Syndrome (SBS), the main cause of chronic intestinal failure. Colon preservation is crucial for spontaneous…”
Get full text
Journal Article -
16
Cell shape regulates global histone acetylation in human mammary epithelial cells
Published in Experimental cell research (15-08-2007)“…Extracellular matrix (ECM) regulates cell morphology and gene expression in vivo; these relationships are maintained in three-dimensional (3D) cultures of…”
Get full text
Journal Article -
17
Remodeling of the residual gastric mucosa after roux-en-y gastric bypass or vertical sleeve gastrectomy in diet-induced obese rats
Published in PloS one (30-03-2015)“…Whereas the remodeling of intestinal mucosa after bariatric surgeries has been the matter of numerous studies to our knowledge, very few reported on the…”
Get full text
Journal Article -
18
Enhanced Ghrelin Levels and Hypothalamic Orexigenic AgRP and NPY Neuropeptide Expression in Models of Jejuno-Colonic Short Bowel Syndrome
Published in Scientific reports (21-06-2016)“…Short bowel syndrome (SBS) patients developing hyperphagia have a better outcome. Gastrointestinal endocrine adaptations help to improve intestinal functions…”
Get full text
Journal Article -
19
Homozygous Leptin Receptor Mutation Due to Uniparental Disomy of Chromosome 1: Response to Bariatric Surgery
Published in The journal of clinical endocrinology and metabolism (01-02-2013)“…Context: Severe early-onset obesity with major hyperphagia associated with hypogonadotropic hypogonadism is recognized as the main clinical presentation of…”
Get full text
Journal Article -
20
Intestinal deletion of leptin signaling alters activity of nutrient transporters and delayed the onset of obesity in mice
Published in The FASEB journal (01-09-2014)“…The importance of B‐isoform of leptin receptor (LEPR‐B) signaling in the hypothalamus, pancreas, or liver has been well characterized, but in the intestine, a…”
Get full text
Journal Article