Search Results - "Le Bescop, Clément"

The DAV132 colon-targeted adsorbent does not interfere with plasma concentrations of antibiotics but prevents antibiotic-related dysbiosis: a randomized phase I trial in healthy volunteers by Messaoudene, Meriem, Ferreira, Stéphanie, Saint-Lu, Nathalie, Ponce, Mayra, Truntzer, Caroline, Boidot, Romain, Le Bescop, Clément, Loppinet, Thomas, Corbel, Tanguy, Féger, Céline, Bertrand, Karine, Elkrief, Arielle, Isaksen, Morten, Vitry, Fabien, Sablier-Gallis, Frédérique, Andremont, Antoine, Bod, Lloyd, Ghiringhelli, François, de Gunzburg, Jean, Routy, Bertrand

“…The deleterious impact of antibiotics (ATB) on the microbiome negatively influences immune checkpoint inhibitors (ICI) response in patients with cancer. We…”
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A systematic review and meta-analysis evaluating the impact of antibiotic use on the clinical outcomes of cancer patients treated with immune checkpoint inhibitors by Crespin, Athéna, Le Bescop, Clément, de Gunzburg, Jean, Vitry, Fabien, Zalcman, Gérard, Cervesi, Julie, Bandinelli, Pierre-Alain

“…Immune checkpoint inhibitors (ICIs) have considerably improved patient outcomes in various cancer types, but their efficacy remains poorly predictable among…”
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278 Systematic review and meta-analysis evaluating the impact of antibiotic use on clinical outcomes of non-small-cell lung cancer patients treated with immune checkpoint inhibitors by Crespin, Athéna, Bandinelli, Pierre-Alain, Bescop, Clément Le, Buffet, Renaud, Gunzburg, Jean De, Vitry, Fabien, Zalcman, Gérard, Cervesi, Julie

“…BackgroundIn recent years, the gut microbiome has increasingly emerged as influencing the response to immune checkpoint inhibitors (ICIs).1–3 Antibiotic (ABX)…”
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671 Update of a systematic review and meta-analysis studying the association between antibiotic use and clinical outcomes of non-small-cell lung cancer patients treated with immune checkpoint inhibitors by Bandinelli, Pierre-Alain, Cervesi, Julie, Bescop, Clément Le, Buffet, Renaud, Gunzburg, Jean De, Zalcman, Gérard

“…BackgroundImmune checkpoint inhibitors (ICIs) have been shown to improve patients‘ clinical outcomes in a variety of cancers, but with variable efficacy. Prior…”
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Incidence of CDI in a Cohort of US Patients with Newly Diagnosed Acute Myeloid Leukemia Receiving Intensive Chemotherapy by Lurienne, Lise, Le Bescop, Clément, Buffet, Renaud, Bandinelli, Pierre-Alain

“…Background: The immunosuppression seen in Acute Myeloid Leukemia (AML) patients due to the intensive chemotherapy and consolidation therapies used to treat…”
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Systematic review and meta-analysis evaluating the impact of antibiotic use on the clinical outcomes of patients with cancer treated with immune checkpoint inhibitors by Zalcman, Gerard, Crespin, Athéna, Cervesi, Julie, Le Bescop, Clément, Buffet, Renaud, de Gunzburg, Jean, Vitry, Fabien, Bandinelli, Pierre-Alain

“…2585 Background: In recent years, the gut microbiome has increasingly emerged as influencing the response to immune checkpoint inhibitors (ICIs) and antibiotic…”
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Abstract 5882: Prevention of antibiotic-induced dysbiosis in human volunteers by DAV132 and preservation of responsiveness to anti-PD-1 demonstrated by transplantation of human feces into tumor-bearing mice by Messaoudene, Meriem, Saint-Lu, Nathalie, Sablier-Gallis, Frédérique, Ferreira, Stéphanie, Ponce, Mayra, Bescop, Clément Le, Loppinet, Thomas, Corbel, Tanguy, Féger, Céline, Vitry, Fabien, Andremont, Antoine, de Gunzburg, Jean, Routy, Bertrand

“…Abstract Background: Over the last decade, studies unraveled the cancer-immune dialogue in the setting of immune checkpoint inhibitors (ICI) and influenced by…”
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