Search Results - "León Contreras, Juan Carlos"

Curcumin prevents mitochondrial dynamics disturbances in early 5/6 nephrectomy: Relation to oxidative stress and mitochondrial bioenergetics by Aparicio‐Trejo, Omar Emiliano, Tapia, Edilia, Molina‐Jijón, Eduardo, Medina‐Campos, Omar Noel, Macías‐Ruvalcaba, Norma Angélica, León‐Contreras, Juan Carlos, Hernández‐Pando, Rogelio, García‐Arroyo, Fernando E., Cristóbal, Magdalena, Sánchez‐Lozada, Laura Gabriela, Pedraza‐Chaverri, José

“…Five‐sixths nephrectomy (5/6NX) is a widely used model to study the mechanisms leading to renal damage in chronic kidney disease (CKD). However, early…”
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Formation of Foamy Macrophages by Tuberculous Pleural Effusions Is Triggered by the Interleukin-10/Signal Transducer and Activator of Transcription 3 Axis through ACAT Upregulation by Genoula, Melanie, Marín Franco, José Luis, Dupont, Maeva, Kviatcovsky, Denise, Milillo, Ayelén, Schierloh, Pablo, Moraña, Eduardo Jose, Poggi, Susana, Palmero, Domingo, Mata-Espinosa, Dulce, González-Domínguez, Erika, León Contreras, Juan Carlos, Barrionuevo, Paula, Rearte, Bárbara, Córdoba Moreno, Marlina Olyissa, Fontanals, Adriana, Crotta Asis, Agostina, Gago, Gabriela, Cougoule, Céline, Neyrolles, Olivier, Maridonneau-Parini, Isabelle, Sánchez-Torres, Carmen, Hernández-Pando, Rogelio, Vérollet, Christel, Lugo-Villarino, Geanncarlo, Sasiain, María Del Carmen, Balboa, Luciana

“…The ability of (Mtb) to persist in its human host relies on numerous immune evasion strategies, such as the deregulation of the lipid metabolism leading to the…”
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Quinacrine, an Antimalarial Drug with Strong Activity Inhibiting SARS-CoV-2 Viral Replication In Vitro by Salas Rojas, Mónica, Silva Garcia, Raúl, Bini, Estela, Pérez de la Cruz, Verónica, León Contreras, Juan Carlos, Hernández Pando, Rogelio, Bastida Gonzalez, Fernando, Davila-Gonzalez, Eduardo, Orozco Morales, Mario, Gamboa Domínguez, Armando, Sotelo, Julio, Pineda, Benjamín

“…Quinacrine (Qx), a molecule used as an antimalarial, has shown anticancer, antiprion, and antiviral activity. The most relevant antiviral activities of Qx are…”
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Antimicrobial Peptide against Mycobacterium Tuberculosis That Activates Autophagy Is an Effective Treatment for Tuberculosis by Peláez Coyotl, Erika A., Barrios Palacios, Jacqueline, Muciño, Gabriel, Moreno-Blas, Daniel, Costas, Miguel, Montiel Montes, Teresa, Diener, Christian, Uribe-Carvajal, Salvador, Massieu, Lourdes, Castro-Obregón, Susana, Espinosa, Octavio Ramos, Mata Espinosa, Dulce, Barrios-Payan, Jorge, León Contreras, Juan Carlos, Corzo, Gerardo, Hernández-Pando, Rogelio, Del Rio, Gabriel

“…Mycobacterium tuberculosis (MTB) is the principal cause of human tuberculosis (TB), which is a serious health problem worldwide. The development of innovative…”
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Activation of STAT3 Regulates Reactive Astrogliosis and Neuronal Death Induced by AβO Neurotoxicity by Toral-Rios, Danira, Patiño-López, Genaro, Gómez-Lira, Gisela, Gutiérrez, Rafael, Becerril-Pérez, Fernando, Rosales-Córdova, Aldebarán, León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, León-Rivera, Ismael, Soto-Cruz, Isabel, Florán-Garduño, Benjamín, Campos-Peña, Victoria

“…Amyloid-beta oligomers (AβO) have been proposed as the most potent neurotoxic and inflammation inducers in Alzheimer's disease (AD). AβO contribute to AD…”
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Comparison of the transcriptome, lipidome, and c-di-GMP production between BCGΔBCG1419c and BCG, with Mincle- and Myd88-dependent induction of proinflammatory cytokines in murine macrophages by Flores-Valdez, Mario Alberto, Peterson, Eliza J. R., Aceves-Sánchez, Michel de Jesús, Baliga, Nitin S., Morita, Yasu S., Sparks, Ian L., Saini, Deepak Kumar, Yadav, Rahul, Lang, Roland, Mata-Espinosa, Dulce, León-Contreras, Juan Carlos, Hernández-Pando, Rogelio

“…We have previously reported the transcriptomic and lipidomic profile of the first-generation, hygromycin-resistant (Hyg R ) version of the BCGΔBCG1419c vaccine…”
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NAC Pre-Administration Prevents Cardiac Mitochondrial Bioenergetics, Dynamics, Biogenesis, and Redox Alteration in Folic Acid-AKI-Induced Cardio-Renal Syndrome Type 3 by Cuevas-López, Belén, Romero-Ramirez, Edgar Ignacio, García-Arroyo, Fernando E, Tapia, Edilia, León-Contreras, Juan Carlos, Silva-Palacios, Alejandro, Roldán, Francisco-Javier, Campos, Omar Noel Medina, Hernandez-Esquivel, Luz, Marín-Hernández, Alvaro, Gonzaga-Sánchez, José Guillermo, Hernández-Pando, Rogelio, Pedraza-Chaverri, José, Sánchez-Lozada, Laura Gabriela, Aparicio-Trejo, Omar Emiliano

“…The incidence of kidney disease is increasing worldwide. Acute kidney injury (AKI) can strongly favor cardio-renal syndrome (CRS) type 3 development. However,…”
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Curcumin prevents paracetamol-induced liver mitochondrial alterations by Granados-Castro, Luis Fernando, Rodríguez-Rangel, Daniela Sarai, Fernández-Rojas, Berenice, León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, Medina-Campos, Omar Noel, Eugenio-Pérez, Dianelena, Pinzón, Enrique, Pedraza-Chaverri, José

“…Objective In the present study was evaluated if curcumin is able to attenuate paracetamol (PCM)‐induced mitochondrial alterations in liver of mice. Methods…”
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The nephroprotection exerted by curcumin in maleate-induced renal damage is associated with decreased mitochondrial fission and autophagy by Molina-Jijón, Eduardo, Aparicio-Trejo, Omar Emiliano, Rodríguez-Muñoz, Rafael, León-Contreras, Juan Carlos, del Carmen Cárdenas-Aguayo, María, Medina-Campos, Omar Noel, Tapia, Edilia, Sánchez-Lozada, Laura Gabriela, Hernández-Pando, Rogelio, Reyes, José L., Arreola-Mendoza, Laura, Pedraza-Chaverri, José

“…We have previously reported that the antioxidant curcumin exerts nephroprotection in maleate‐induced renal damage, a model associated with oxidative stress…”
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Nucleotide-oligomerizing domain-1 (NOD1) receptor activation induces pro-inflammatory responses and autophagy in human alveolar macrophages by Juárez, Esmeralda, Carranza, Claudia, Hernández-Sánchez, Fernando, Loyola, Elva, Escobedo, Dante, León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, Torres, Martha, Sada, Eduardo

“…Nucleotide-binding oligomerizing domain-1 (NOD1) is a cytoplasmic receptor involved in recognizing bacterial peptidoglycan fragments that localize to the…”
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Sulforaphane induces differential modulation of mitochondrial biogenesis and dynamics in normal cells and tumor cells by Negrette-Guzmán, Mario, Huerta-Yepez, Sara, Vega, Mario I., León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, Medina-Campos, Omar Noel, Rodríguez, Esteban, Tapia, Edilia, Pedraza-Chaverri, José

“…Antioxidant-based chemotherapy has been intensely debated. Herein, we show that sulforaphane (SFN) induced mitochondrial biogenesis followed by mitochondrial…”
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Mycobacterium tuberculosis Infection Induces BCSFB Disruption but No BBB Disruption In Vivo: Implications in the Pathophysiology of Tuberculous Meningitis by Sánchez-Garibay, Carlos, Salinas-Lara, Citlaltepetl, Gómez-López, Marcos Artemio, Soto-Rojas, Luis O., Castillón-Benavides, Nidia Karen, Castillón-Benavides, Omar Jorge, Hernández-Campos, María Elena, Hernández-Pando, Rogelio, Marquina-Castillo, Brenda, Flores-Barrada, Manuel Alejandro, Choreño-Parra, José Alberto, León-Contreras, Juan Carlos, Tena-Suck, Martha Lilia, Mata-Espinosa, Dulce Adriana, Nava, Porfirio, Medina-Mendoza, Jessica, Rodríguez-Balderas, Cesar Augusto

“…Central nervous system (CNS) tuberculosis is the most lethal and devastating form among the diseases caused by Mycobacterium tuberculosis. The mechanisms by…”
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Klf10 favors Mycobacterium tuberculosis survival by impairing IFN‐γ production and preventing macrophages reprograming to macropinocytosis by Madrid‐Paulino, Edgardo, Mata‐Espinosa, Dulce, León‐Contreras, Juan Carlos, Serrano‐Fujarte, Isela, Díaz de León‐Guerrero, Sol, Villaseñor, Tomás, Ramon‐Luing, Lucero, Puente, José L., Chavez‐Galan, Leslie, Hernández‐Pando, Rogelio, Pérez‐Martínez, Leonor, Pedraza‐Alva, Gustavo

“…Mycobacterium tuberculosis has developed diverse mechanisms to survive inside phagocytic cells, such as macrophages. Phagocytosis is a key process in…”
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Cardioprotective kinase signaling to subsarcolemmal and interfibrillar mitochondria is mediated by caveolar structures by García-Niño, Wylly Ramsés, Correa, Francisco, Rodríguez-Barrena, Julia Isabel, León-Contreras, Juan Carlos, Buelna-Chontal, Mabel, Soria-Castro, Elizabeth, Hernández-Pando, Rogelio, Pedraza-Chaverri, José, Zazueta, Cecilia

“…The demonstration that caveolin-3 overexpression reduces myocardial ischemia/reperfusion injury and our own finding that multiprotein signaling complexes…”
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Temporal Alterations in Mitochondrial β-Oxidation and Oxidative Stress Aggravate Chronic Kidney Disease Development in 5/6 Nephrectomy Induced Renal Damage by Aparicio-Trejo, Omar Emiliano, Rojas-Morales, Pedro, Avila-Rojas, Sabino Hazael, León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, Jiménez-Uribe, Alexis Paulina, Prieto-Carrasco, Rodrigo, Sánchez-Lozada, Laura Gabriela, Pedraza-Chaverri, José, Tapia, Edilia

“…Five-sixths nephrectomy (5/6Nx) model is widely used for studying the mechanisms involved in chronic kidney disease (CKD) progression, a kidney pathology that…”
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C-phycocyanin prevents cisplatin-induced mitochondrial dysfunction and oxidative stress by Fernández-Rojas, Berenice, Rodríguez-Rangel, Daniela Sarai, Granados-Castro, Luis Fernando, Negrette-Guzmán, Mario, León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, Molina-Jijón, Eduardo, Reyes, José L., Zazueta, Cecilia, Pedraza-Chaverri, José

“…The potential of C-phycocyanin (C-PC) to prevent cisplatin (CP)-induced kidney mitochondrial dysfunction was determined in CD-1 male mice. The CP-induced…”
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Inhibition of the nitric oxide/cyclic guanosine monophosphate pathway limited the cardioprotective effect of post-conditioning in hearts with apical myocardial infarction by Correa, Francisco, Buelna-Chontal, Mabel, Chagoya, Victoria, García-Rivas, Gerardo, Vigueras, Rosa María, Pedraza-Chaverri, José, García-Niño, Wylly Ramsés, Hernández-Pando, Rogelio, León-Contreras, Juan Carlos, Zazueta, Cecilia

“…Reperfusion damage involves opening of the mitochondrial permeability transition pore (mPTP) and loss of ATP synthesis. Several cardioprotective pathways are…”
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Progressive Reduction in Mitochondrial Mass Is Triggered by Alterations in Mitochondrial Biogenesis and Dynamics in Chronic Kidney Disease Induced by 5/6 Nephrectomy by Prieto-Carrasco, Rodrigo, García-Arroyo, Fernando E, Aparicio-Trejo, Omar Emiliano, Rojas-Morales, Pedro, León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, Sánchez-Lozada, Laura Gabriela, Tapia, Edilia, Pedraza-Chaverri, José

“…The five-sixth nephrectomy (5/6Nx) model is widely used to study the mechanisms involved in chronic kidney disease (CKD) progression. Mitochondrial impairment…”
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Curcumin Attenuates Gentamicin-Induced Kidney Mitochondrial Alterations: Possible Role of a Mitochondrial Biogenesis Mechanism by Pedraza-Chaverri, José, Madero, Magdalena, Hernández-Pando, Rogelio, León-Contreras, Juan Carlos, Huerta-Yepez, Sara, Zazueta, Cecilia, Tapia, Edilia, García-Niño, Wylly Ramsés, Negrette-Guzmán, Mario, Aparicio-Trejo, Omar Emiliano

“…It has been shown that curcumin (CUR), a polyphenol derived from Curcuma longa, exerts a protective effect against gentamicin- (GM-) induced nephrotoxicity in…”
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In Vitro, In Vivo and In Silico Assessment of the Antimicrobial and Immunomodulatory Effects of a Water Buffalo Cathelicidin (WBCATH) in Experimental Pulmonary Tuberculosis by Palacios, Jacqueline Barrios, Barrios-Payán, Jorge, Mata-Espinosa, Dulce, Lara-Espinosa, Jacqueline V, León-Contreras, Juan Carlos, Lushington, Gerald H, Melgarejo, Tonatiuh, Hernández-Pando, Rogelio

“…Tuberculosis (TB) is considered the oldest pandemic in human history. The emergence of multidrug-resistant (MDR) strains is currently considered a serious…”
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