Search Results - "León‐López, Rafael"
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Miniaturized Biotrickling Filters and Capillary Microbioreactors for Process Intensification of VOC Treatment with Intended Application to Indoor Air
Published in Environmental science & technology (05-02-2019)“…Typical biofilters and biotrickling filters used for volatile organic compounds (VOCs) control have treatment rates limited to 30–200 g m–3 h–1, mostly because…”
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Early Use of Sarilumab in Patients Hospitalized with COVID-19 Pneumonia and Features of Systemic Inflammation: the SARICOR Randomized Clinical Trial
Published in Antimicrobial agents and chemotherapy (15-02-2022)“…The objective of this study was to investigate the efficacy and safety of early treatment with sarilumab, added to standard of care (SOC), in hospitalized…”
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Role of IP-10 to Predict Clinical Progression and Response to IL-6 Blockade With Sarilumab in Early COVID-19 Pneumonia. A Subanalysis of the SARICOR Clinical Trial
Published in Open forum infectious diseases (01-04-2023)“…Abstract Background The Clinical Trial of Sarilumab in Adults With COVID-19 (SARICOR) showed that patients with coronavirus disease 2019 (COVID-19) pneumonia…”
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Efficacy and safety of early treatment with sarilumab in hospitalised adults with COVID-19 presenting cytokine release syndrome (SARICOR STUDY): protocol of a phase II, open-label, randomised, multicentre, controlled clinical trial
Published in BMJ open (14-11-2020)“…IntroductionAbout 25% of patients with COVID-19 develop acute respiratory distress syndrome (ARDS) associated with a high release of pro-inflammatory cytokines…”
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Severe trauma patients and nursing practice‐associated infections
Published in International journal of nursing practice (01-10-2020)“…Aims Our study examined factors influencing the development of healthcare‐associated infections in the intensive care unit (ICU) of a tertiary hospital in…”
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Risk Factors for Multidrug-Resistant Gram-Negative Bacteria Carriage upon Admission to the Intensive Care Unit
Published in International journal of environmental research and public health (18-01-2022)“…Multidrug-resistant Gram-negative bacteria (MDR-GNB) are microorganisms that have acquired resistance to extended-spectrum antibacterials and constitute an…”
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Age-related injury patterns in Spanish trauma ICU patients. Results from the RETRAUCI
Published in Injury (01-09-2016)“…ABSTRACT Background Injury patterns may differ in trauma patients when age is considered. This information is relevant in the management of trauma patients and…”
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Recommendations for antibiotic selection for severe nosocomial infections
Published in Revista española de quimioterapia (01-10-2021)“…Severe infection and its evolution to sepsis are becoming more prevalent every day and are among the leading causes of critical illness and mortality. Proper…”
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Aerobic desulfurization of biogas by acidic biotrickling filtration in a randomly packed reactor
Published in Journal of hazardous materials (15-09-2014)“…•Desulfurization of high loads of H2S is feasible by acidic biotrickling filtration.•Robustness of the process is demonstrated in the long-term…”
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Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Published in Genome medicine (05-04-2023)“…We previously reported that impaired type I IFN activity, due to inborn errors of TLR3- and TLR7-dependent type I interferon (IFN) immunity or to…”
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Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Published in Genome medicine (06-01-2024)Get full text
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PROPHETIC EU: Prospective Identification of Pneumonia in Hospitalized Patients in the Intensive Care Unit in European and United States Cohorts
Published in Open forum infectious diseases (01-07-2022)“…Abstract Background The prospective identification of patients at high risk for hospital-acquired/ventilator-associated bacterial pneumonia may improve…”
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EPICO PROJECT. Development of educational recommendations using the DELPHI technique on invasive candidiasis in non- neutropenic critically ill adult patients
Published in Revista española de quimioterapia (01-06-2013)“…Although there has been an improved management of Invasive Candidiasis in the last decade, controversial issues still remain, especially in the diagnostic and…”
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