Search Results - "León, Eduardo"

Towards a holistic framework for sustainable value analysis in business models: A tool for sustainable development by Méndez-León, Eduardo, Reyes, Tatiana, Díaz-Pichardo, René

“…This article analyzes how the concept of sustainable value is used in the business model literature to understand and structure the concepts used in analyzing…”
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Metformin inhibition of colorectal cancer cell migration is associated with rebuilt adherens junctions and FAK downregulation by Amable, Gastón, Martínez‐León, Eduardo, Picco, María Elisa, Nemirovsky, Sergio I., Rozengurt, Enrique, Rey, Osvaldo

“…E‐cadherin, a central component of the adherens junction (AJ), is a single‐pass transmembrane protein that mediates cell–cell adhesion. The loss of E‐cadherin…”
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What is unique about sustainable business models for the base of the pyramid? by Méndez-León, Eduardo, Díaz-Pichardo, René, Reyes, Tatiana, del Rosario Reyes-Santiago, María

“…Research on sustainable business models (SBMs) has been hindered by the use of traditional business model (BM) components indiscriminately applied to explain…”
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A scalable and normalized reef status index for assessing fish trophic structure reveals conservation gaps by Favoretto, Fabio, López-Sagástegui, Catalina, León-Solórzano, Eduardo, Aburto-Oropeza, Octavio

“…•Introducing the Normalized Reef Status Index (NRSI) for swift evaluation of fishing impact on reef fish populations.•Utilized the NRSI to assess 346 reefs…”
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Collaborative care for depression and suicide prevention: a feasible intervention within the Mexican health system by Durand-Arias, Sol, Cordoba, Gloria, Borges, Guilherme, Madrigal-de León, Eduardo Á

“…Mexico faces an enormous challenge in attending mental health disorders with depression rising as one of the five main contributors to disability adjusted life…”
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Fibronectin modulates the endocannabinoid system through the cAMP/PKA pathway during human sperm capacitation by Martínez‐León, Eduardo, Osycka‐Salut, Claudia, Signorelli, Janetti, Kong, Milene, Morales, Patricio, Pérez‐Martínez, Silvina, Díaz, Emilce Silvina

“…Fibronectin (Fn) enhances human sperm capacitation via the cAMP/PKA pathway, and the endocannabinoid system participates in this process. Moreover, Fn has been…”
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An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogenesis by García-Domínguez, Daniel J, Hontecillas-Prieto, Lourdes, León, Eduardo Andrés, Sánchez-Molina, Sara, Rodríguez-Núñez, Pablo, Morón, Francisco J, Hajji, Nabil, Mackintosh, Carlos, de Álava, Enrique

“…The presence of the chimeric EWSR1-FLI1 oncoprotein is the main and initiating event defining Ewing sarcoma (ES). The dysregulation of epigenomic and proteomic…”
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Mental Health Problems among COVID-19 Frontline Healthcare Workers and the Other Country-Level Epidemics: The Case of Mexico by Robles, Rebeca, Morales-Chainé, Silvia, Bosch, Alejandro, Astudillo-García, Claudia, Feria, Miriam, Infante, Sara, Alcocer-Castillejos, Natasha, Ascencio, Leticia, Real-Ramírez, Janet, Díaz, Dulce, Gómez-Estrada, Héctor Francisco, Becerra, Claudia, Escamilla, Raúl, López-Montoya, Alejandra, Beristain-Aguirre, Ana, Vega, Hamid, Álvarez-Icaza, Dení, Rodríguez, Evelyn, Durand, Sol, Fresán, Ana, Medina-Mora, María-Elena, Fernández-Cáceres, Carmen, Madrigal de León, Eduardo Ángel

“…COVID-19 frontline healthcare workers (FHCW) are struggling to cope with challenges that threaten their wellbeing. We examine the frequency and predictors of…”
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Genome-wide integrated DNA methylome and transcriptome analysis reveals a strong dysregulated myeloid component in the epigenetic landscape of Systemic Sclerosis by Martínez-López, Javier, Ortiz-Fernandez, Lourdes, Estupiñán-Moreno, Elkyn, Kerick, Martin, Andrés-León, Eduardo, Terron-Camero, Laura C, Carnero-Montoro, Elena, Barturen, Guillermo, Beretta, Lorenzo, Almeida, Isabel, Alarcón-Riquelme, Marta E, Ballestar, Esteban, Acosta-Herrera, Marialbert, Martín, Javier

“…Non-genetic factors influence Systemic Sclerosis (SSc) pathogenesis, underscoring epigenetics as a relevant contributor to the disease. We aimed to unravel DNA…”
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Trends and effect of marginalization on diabetes mellitus-related mortality in Mexico from 1990 to 2019 by Gutiérrez-León, Eduardo, Escamilla-Santiago, Ricardo Antonio, Martínez-Amezcua, Pablo, Bilal, Usama, Lazo, Mariana, Ogaz-González, Rafael, López-Cervantes, Malaquías

“…Diabetes mellitus (DM) is currently one of the leading causes of mortality worldwide. However, the disease evolves differently across countries. This study…”
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El lenguaje como máquina: Deleuze y Guattari en la lingüística contemporánea by Alberto León, Eduardo

“…En su obra Mil mesetas, Deleuze y Guattari ofrecen una perspectiva singular sobre el lenguaje, concebido como un sistema de signos interconectados y fluidos,…”
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Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses by Rodríguez-Ubreva, Javier, Arutyunyan, Anna, Bonder, Marc Jan, Del Pino-Molina, Lucía, Clark, Stephen J., de la Calle-Fabregat, Carlos, Garcia-Alonso, Luz, Handfield, Louis-François, Ciudad, Laura, Andrés-León, Eduardo, Krueger, Felix, Català-Moll, Francesc, Rodríguez-Cortez, Virginia C., Polanski, Krzysztof, Mamanova, Lira, van Dongen, Stijn, Kiselev, Vladimir Yu, Martínez-Saavedra, María T., Heyn, Holger, Martín, Javier, Warnatz, Klaus, López-Granados, Eduardo, Rodríguez-Gallego, Carlos, Stegle, Oliver, Kelsey, Gavin, Vento-Tormo, Roser, Ballestar, Esteban

“…Common variable immunodeficiency (CVID), the most prevalent symptomatic primary immunodeficiency, displays impaired terminal B-cell differentiation and…”
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Impact and Management of COVID-19 Among Healthcare Workers in Two Acute Care Hospitals and Two Associated Long-term Care Centres in Barcelona, Spain by Montero-Moraga, Jose Maria, Buron, Andrea, Sala, Maria, Santia, Paula, Lupia, Martina, Beltrán, Ana, Villar, Rocío, Horcajada, Juan Pablo, Castells, Xavier, Gil, Oscar Díaz, León, Eduardo Padilla, Serra, Consol

“…Objective:To describe the characteristics of COVID-19-related episodes in healthcare workers (HCW) of two hospitals.Methods:Prospective study of HCW with…”
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The new Uruguayan private international law: an open door to party autonomy in international contracts by Florio de León, Eduardo

“…Abstract On 17 November 2020, the General Law on Private International Law (Law 19.920) was approved. This Law resulted from a process of hard work that took…”
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Remote crisis intervention and suicide risk management in COVID-19 frontline healthcare workers by Robles, Rebeca, Infante, Sara, Feria, Miriam, Arango, Iván, Tirado, Elsa, Rodríguez-Delgado, Andrés, Miranda, Edgar, Fresán, Ana, Becerra, Claudia, Escamilla, Raul, Madrigal de León, Eduardo Angel

“…IntroductionDespite the propagation of virtual mental health services for vulnerable groups during COVID-19 pandemic, the implementation and evaluation of…”
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Potential poleward distribution shift of dolphinfish (Coryphaena hippurus) along the southern California Current System by Salvadeo, Christian, Auliz-Ortiz, Daniel M., Petatán-Ramírez, David, Reyes-Bonilla, Héctor, Ivanova-Bonchera, Antonina, Juárez-León, Eduardo

“…The dolphinfish ( Coryphaena hippurus Linnaeus, 1758) is an epipelagic top-predator that is globally distributed in tropical and subtropical waters. In the…”
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Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection by Barmada, Anis, Handfield, Louis‐François, Godoy‐Tena, Gerard, Calle‐Fabregat, Carlos, Ciudad, Laura, Arutyunyan, Anna, Andrés‐León, Eduardo, Hoo, Regina, Porter, Tarryn, Oszlanczi, Agnes, Richardson, Laura, Calero‐Nieto, Fernando J., Wilson, Nicola K., Marchese, Domenica, Sancho‐Serra, Carmen, Carrillo, Jorge, Presas‐Rodríguez, Silvia, Ramo‐Tello, Cristina, Ruiz‐Sanmartin, Adolfo, Ferrer, Ricard, Ruiz‐Rodriguez, Juan Carlos, Martínez‐Gallo, Mónica, Munera‐Campos, Mónica, Carrascosa, Jose Manuel, Göttgens, Berthold, Heyn, Holger, Prigmore, Elena, Casafont‐Solé, Ivette, Solanich, Xavier, Sánchez‐Cerrillo, Ildefonso, González‐Álvaro, Isidoro, Raimondo, Maria Gabriella, Ramming, Andreas, Martin, Javier, Martínez‐Cáceres, Eva, Ballestar, Esteban, Vento‐Tormo1, Roser, Rodríguez‐Ubreva, Javier

“…In COVID‐19, hyperinflammatory and dysregulated immune responses contribute to severity. Patients with pre‐existing autoimmune conditions can therefore be at…”
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Multidisciplinary obesity treatment: Ten considerations from a mental health perspective by Esquivias-Zavala, Héctor, Caballero Romo, Alejandro, Madrigal de León, Eduardo

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The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity by Lynch, Cian J., Bernad, Raquel, Calvo, Isabel, Nóbrega-Pereira, Sandrina, Ruiz, Sergio, Ibarz, Nuria, Martinez-Val, Ana, Graña-Castro, Osvaldo, Gómez-López, Gonzalo, Andrés-León, Eduardo, Espinosa Angarica, Vladimir, del Sol, Antonio, Ortega, Sagrario, Fernandez-Capetillo, Oscar, Rojo, Enrique, Munoz, Javier, Serrano, Manuel

“…The RNA polymerase II-associated protein 1 (RPAP1) is conserved across metazoa and required for stem cell differentiation in plants; however, very little is…”
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Prp40 and early events in splice site definition by Becerra, Soraya, Andrés-León, Eduardo, Prieto-Sánchez, Silvia, Hernández-Munain, Cristina, Suñé, Carlos

“…The alternative splicing (AS) of precursor messenger RNA (pre‐mRNA) is a tightly regulated process through which introns are removed to leave the resulting…”
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