Search Results - "León, Alberto J"

Raltitrexed-Modified Gold and Silver Nanoparticles for Targeted Cancer Therapy: Cytotoxicity Behavior In Vitro on A549 and HCT-116 Human Cancer Cells by Morey, Jeroni, Llinás, Pere, Bueno-Costa, Alberto, León, Alberto J, Piña, M Nieves

“…Two different raltitrexed gold and silver nanoparticles for the delivery of an antitumoral drug into cancer cells were synthesized and characterized. A…”
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Effective Elimination and Biodegradation of Polycyclic Aromatic Hydrocarbons from Seawater through the Formation of Magnetic Microfibres by Gutiérrez, M Susana, León, Alberto J, Duel, Paulino, Bosch, Rafael, Piña, M Nieves, Morey, Jeroni

“…Supramolecular aggregates formed between polycyclic aromatic hydrocarbons and either naphthalene or perylene-derived diimides have been anchored in magnetite…”
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CXCL10 contributes to p38-mediated apoptosis in primary T lymphocytes in vitro by Sidahmed, Abubaker M.E., León, Alberto J., Bosinger, Steven E., Banner, David, Danesh, Ali, Cameron, Mark J., Kelvin, David J.

“…► Effects of CXCL10 in human T lymphocytes in terms of apoptosis and survival. ► The signaling pathways that are involved in the process were studied. ► New…”
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Immunity toward H1N1 influenza hemagglutinin of historical and contemporary strains suggests protection and vaccine failure by Huang, Stephen S. H., Lin, Zhen, Banner, David, León, Alberto J., Paquette, Stéphane G., Rubin, Barry, Rubino, Salvatore, Guan, Yi, Kelvin, David J., Kelvin, Alyson A.

“…Evolution of H1N1 influenza A outbreaks of the past 100 years is interesting and significantly complex and details of H1N1 genetic drift remains unknown. Here…”
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Topographic mapping of the glioblastoma proteome reveals a triple-axis model of intra-tumoral heterogeneity by Lam, K. H. Brian, Leon, Alberto J., Hui, Weili, Lee, Sandy Che-Eun, Batruch, Ihor, Faust, Kevin, Klekner, Almos, Hutóczki, Gábor, Koritzinsky, Marianne, Richer, Maxime, Djuric, Ugljesa, Diamandis, Phedias

“…Glioblastoma is an aggressive form of brain cancer with well-established patterns of intra-tumoral heterogeneity implicated in treatment resistance and…”
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Inhibition of influenza A virus infection by ginsenosides by Dong, Wei, Farooqui, Amber, Leon, Alberto J, Kelvin, David J

“…Influenza viruses cause mild to severe respiratory infections in humans. Due to efficient means of transmission, the viruses infect human population on a large…”
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Sequencing, Annotation, and Characterization of the Influenza Ferret Infectome by León, Alberto J, Banner, David, Xu, Luoling, Ran, Longsi, Peng, Zhiyu, Yi, Kang, Chen, Chao, Xu, Fengping, Huang, Jinrong, Zhao, Zhen, Lin, Zhen, Huang, Stephen H S, Fang, Yuan, Kelvin, Alyson A, Ross, Ted M, Farooqui, Amber, Kelvin, David J

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Host gene expression profiles in ferrets infected with genetically distinct henipavirus strains by Leon, Alberto J, Borisevich, Viktoriya, Boroumand, Nahal, Seymour, Robert, Nusbaum, Rebecca, Escaffre, Olivier, Xu, Luoling, Kelvin, David J, Rockx, Barry

“…Henipavirus infection causes severe respiratory and neurological disease in humans that can be fatal. To characterize the pathogenic mechanisms of henipavirus…”
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High Levels of Proinflammatory Cytokines, but Not Markers of Tissue Injury, in Unaffected Intestinal Areas from Patients with IBD by León, Alberto J, Gómez, Emma, Garrote, Jose A, Bernardo, David, Barrera, Asterio, Marcos, Jose L, Fernández-Salazar, Luis, Velayos, Benito, Blanco-Quirós, Alfredo, Arranz, Eduardo

“…Intestinal alterations in IBD are triggered and maintained by an overexpression of proinflammatory cytokines. Additionally, increased immune activation has…”
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Pathogenic influenza B virus in the ferret model establishes lower respiratory tract infection by Huang, Stephen S H, Banner, David, Paquette, Stephane G, Leon, Alberto J, Kelvin, Alyson A, Kelvin, David J

“…Influenza B viruses have become increasingly more prominent during influenza seasons. Influenza B infection is typically considered a mild disease and receives…”
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Pax9 is required for cardiovascular development and interacts with Tbx1 in the pharyngeal endoderm to control 4th pharyngeal arch artery morphogenesis by Phillips, Helen M, Stothard, Catherine A, Shaikh Qureshi, Wasay M, Kousa, Anastasia I, Briones-Leon, J Alberto, Khasawneh, Ramada R, O'Loughlin, Chloe, Sanders, Rachel, Mazzotta, Silvia, Dodds, Rebecca, Seidel, Kerstin, Bates, Timothy, Nakatomi, Mitsushiro, Cockell, Simon J, Schneider, Jürgen E, Mohun, Timothy J, Maehr, René, Kist, Ralf, Peters, Heiko, Bamforth, Simon D

“…Developmental defects affecting the heart and aortic arch arteries are a significant phenotype observed in individuals with 22q11 deletion syndrome and are…”
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Differential Pathological and Immune Responses in Newly Weaned Ferrets Are Associated with a Mild Clinical Outcome of Pandemic 2009 H1N1 Infection by HUANG, Stephen S. H, BANNER, David, KELVIN, David J, KELVIN, Alyson A, DEGOUSEE, Norbert, LEON, Alberto J, LOULING XU, PAQUETTE, Stephane G, KANAGASABAI, Thirumagal, YUAN FANG, RUBINO, Salvatore, RUBIN, Barry

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Lack of innate interferon responses during SARS coronavirus infection in a vaccination and reinfection ferret model by Cameron, Mark J, Kelvin, Alyson A, Leon, Alberto J, Cameron, Cheryl M, Ran, Longsi, Xu, Luoling, Chu, Yong-Kyu, Danesh, Ali, Fang, Yuan, Li, Qianjun, Anderson, Austin, Couch, Ronald C, Paquette, Stephane G, Fomukong, Ndingsa G, Kistner, Otfried, Lauchart, Manfred, Rowe, Thomas, Harrod, Kevin S, Jonsson, Colleen B, Kelvin, David J

“…In terms of its highly pathogenic nature, there remains a significant need to further define the immune pathology of SARS-coronavirus (SARS-CoV) infection, as…”
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Downy mildew (Pl ₈ and Pl ₁₄ ) and rust (R Adv ) resistance genes reside in close proximity to tandemly duplicated clusters of non-TIR-like NBS-LRR-encoding genes on sunflower chromosomes 1 and 13 by Bachlava, Eleni, Radwan, Osman E, Abratti, Gustavo, Tang, Shunxue, Gao, Wenxiang, Heesacker, Adam F, Bazzalo, Maria E, Zambelli, Andres, Leon, Alberto J, Knapp, Steven J

“…Nucleotide binding site-leucine rich repeat (NBS-LRR) proteins are encoded by a ubiquitous gene family in sunflower and frequently harbor disease resistance…”
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Early gene expression events in ferrets in response to SARS coronavirus infection versus direct interferon-alpha2b stimulation by Danesh, Ali, Cameron, Cheryl M, León, Alberto J, Ran, Longsi, Xu, Luoling, Fang, Yuan, Kelvin, Alyson A, Rowe, Thomas, Chen, Honglin, Guan, Yi, Jonsson, Colleen B, Cameron, Mark J, Kelvin, David J

“…Abstract Type I interferons (IFNs) are essential to the clearance of viral diseases, however, a clear distinction between genes upregulated by direct…”
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Seasonal H1N1 Influenza Virus Infection Induces Cross-Protective Pandemic H1N1 Virus Immunity through a CD8-Independent, B Cell-Dependent Mechanism by YUAN FANG, BANNER, David, KELVIN, David J, KELVIN, Alyson A, HUANG, Stephen S. H, PAIGE, Christopher J, CORFE, Steven A, KANE, Kevin P, BLEACKLEY, R. Chris, ROWE, Thomas, LEON, Alberto J

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Cytokine, Chemokine and Immune Activation Pathway Profiles in Celiac Disease: An Immune System Activity Screening by Expression Macroarrays by Garrote, José A., Gómez, Emma, León, Alberto J., Bernardo, David, Calvo, Carmen, Fernández-Salazar, Luis, Blanco-Quirós, Alfredo, Arranz, Eduardo

“…Abstract non disponibile…”
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Molecular Characterization of In Vivo Adjuvant Activity in Ferrets Vaccinated against Influenza Virus by Fang, Yuan, Rowe, Thomas, Leon, Alberto J, Banner, David, Danesh, Ali, Xu, Luoling, Ran, Longsi, Bosinger, Steven E, Guan, Yi, Chen, Honglin, Cameron, Cheryl C, Cameron, Mark J, Kelvin, David J

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Single nucleotide polymorphisms and linkage disequilibrium in sunflower by Kolkman, J.M, Berry, S.T, Leon, A.J, Slabaugh, M.B, Tang, S, Gao, W, Shintani, D.K, Burke, J.M, Knapp, S.J

“…Genetic diversity in modern sunflower (Helianthus annuus L.) cultivars (elite oilseed inbred lines) has been shaped by domestication and breeding bottlenecks…”
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Induction of Fas mediated caspase-8 independent apoptosis in immune cells by Armigeres subalbatus saliva by Liu, Shanshan, Kelvin, David J, Leon, Alberto J, Jin, Liqun, Farooqui, Amber

“…It is widely recognized that the introduction of saliva of bloodsucking arthropods at the site of pathogen transmission might play a central role in…”
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