Search Results - "Leão, Tiago F"
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Nature's Combinatorial Biosynthesis Produces Vatiamides A–F
Published in Angewandte Chemie International Edition (01-07-2019)“…Hybrid type I PKS/NRPS biosynthetic pathways typically proceed in a collinear manner wherein one molecular building block is enzymatically incorporated in a…”
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Heterologous Expression of Cryptomaldamide in a Cyanobacterial Host
Published in ACS synthetic biology (18-12-2020)“…Filamentous marine cyanobacteria make a variety of bioactive molecules that are produced by polyketide synthases, nonribosomal peptide synthetases, and hybrid…”
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3
Metabolomic Profiling of Guadua Species and Its Correlation with Antioxidant and Cytotoxic Activities
Published in ACS omega (03-09-2024)“…Bamboo plants are widely used in Asian traditional medicine for various health issues and exhibit therapeutic potential. Guadua species are renowned bamboos…”
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Integrating mass spectrometry and genomics for cyanobacterial metabolite discovery
Published in Journal of industrial microbiology & biotechnology (01-03-2016)“…Filamentous marine cyanobacteria produce bioactive natural products with both potential therapeutic value and capacity to be harmful to human health. Genome…”
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Untargeted metabolomics approach and molecular networking analysis reveal changes in chemical composition under the influence of altitudinal variation in bamboo species
Published in Frontiers in molecular biosciences (24-05-2023)“…Bamboo species have traditionally been used as building material and potential source of bioactive substances, as they produce a wide variety of phenolic…”
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Characterization of a tetrameric proanthocyanidin in Stryphnodendron pulcherrimum and an overview on potential health benefits of condensed tannins via interaction with gut microbiota
Published in Journal of functional foods (01-10-2023)“…[Display omitted] •A tetrameric condensed tannin of (epi)catechin-(epi)gallocatechin was described for the first time in the barks from Stryphnodendron…”
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NPOmix: A machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters
Published in PNAS nexus (01-11-2022)“…Microbial specialized metabolites are an important source of and inspiration for many pharmaceuticals, biotechnological products and play key roles in…”
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8
Nature's Combinatorial Biosynthesis Produces Vatiamides A–F
Published in Angewandte Chemie (01-07-2019)“…Hybrid type I PKS/NRPS biosynthetic pathways typically proceed in a collinear manner wherein one molecular building block is enzymatically incorporated in a…”
Get full text
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9
Quick-start infrastructure for untargeted metabolomics analysis in GNPS
Published in Nature metabolism (01-07-2021)Get full text
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10
Artificial intelligence for natural product drug discovery
Published in Nature reviews. Drug discovery (01-11-2023)“…Developments in computational omics technologies have provided new means to access the hidden diversity of natural products, unearthing new potential for drug…”
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11
Quick-start for Untargeted Metabolomics Analysis in GNPS
Published in Nature metabolism (01-07-2021)Get full text
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